The relevance of the intestinal crypt and enterocyte in regulating iron absorption (Q36808730)

16 August 2017

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title

The relevance of the intestinal crypt and enterocyte in regulating iron absorption (English)

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16 August 2017

Phillip S Oates

1

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16 August 2017

publication date

1 May 2007

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16 August 2017

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16 August 2017

volume

455

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16 August 2017

issue

2

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16 August 2017

page(s)

201-213

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Iron imports. I. Intestinal iron absorption and its regulation

16 August 2017

cites work

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https://api.crossref.org/works/10.1007/S00424-007-0264-9

Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00424-007-0264-9

DMT1 and FPN1 expression during infancy: developmental regulation of iron absorption

21 January 2018

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https://api.crossref.org/works/10.1007/S00424-007-0264-9

Tissue-specific changes in iron metabolism genes in mice following phenylhydrazine-induced haemolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00424-007-0264-9

Gastrointestinal function, divalent metal transporter-1 expression and intestinal iron absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00424-007-0264-9

Intestinal expression of genes involved in iron absorption in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00424-007-0264-9

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

21 January 2018

1 reference

12 December 2020

Effect of transfused reticulocytes on iron exchange

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12 December 2020

Gene expression of divalent metal transporter 1 and transferrin receptor in duodenum of Belgrade rats

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12 December 2020

Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1

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12 December 2020

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

1 reference

12 December 2020

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell.

1 reference

12 December 2020

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

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12 December 2020

Molecular and cellular mechanisms underlying iron transport deficiency in microcytic anemia

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12 December 2020

Genes that modify the hemochromatosis phenotype in mice

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12 December 2020

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

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12 December 2020

Down-regulation of iron regulatory protein 1 activities and expression in superoxide dismutase 1 knock-out mice is not associated with alterations in iron metabolism

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12 December 2020

Relationship between duodenal cytosolic aconitase activity and iron status in the mouse

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12 December 2020

Role of HFE in iron metabolism, hereditary haemochromatosis, anaemia of chronic disease, and secondary iron overload

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12 December 2020

Post-transcriptional regulation of human iron metabolism by iron regulatory proteins

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12 December 2020

Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.

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12 December 2020

Duodenal metal-transporter (DMT-1, NRAMP-2) expression in patients with hereditary haemochromatosis

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12 December 2020

Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption

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12 December 2020

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

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12 December 2020

Soluble transferrin receptor-1 levels in mice do not affect iron absorption

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12 December 2020

Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin

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12 December 2020

Pathways for the regulation of body iron homeostasis in response to experimental iron overload.

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12 December 2020

Serum transferrin receptor is a truncated form of tissue receptor

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12 December 2020

Genetic disorders of iron overload and the novel "ferroportin disease"

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12 December 2020

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

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12 December 2020

Iron Regulates the Intracellular Degradation of Iron Regulatory Protein 2 by the Proteasome

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12 December 2020

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

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12 December 2020

The role of hepcidin and ferroportin in iron absorption

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12 December 2020

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

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12 December 2020

Haemochromatosis protein is expressed on the terminal web of enterocytes in proximal small intestine of the rat

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12 December 2020

Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat

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12 December 2020

Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis.

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12 December 2020

Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

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12 December 2020

Iron release from human monocytes after erythrophagocytosis in vitro: an investigation in normal subjects and hereditary hemochromatosis patients

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12 December 2020

Iron regulatory protein as an endogenous sensor of iron in rat intestinal mucosa. Possible implications for the regulation of iron absorption

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12 December 2020

Molecular analysis of iron overload in β2-microglobulin-deficient mice

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12 December 2020

THE ROLE OF THE INTESTINE IN IRON KINETICS.

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12 December 2020

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

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12 December 2020

Physiologic systemic iron metabolism in mice deficient for duodenal Hfe

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12 December 2020

Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells.

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12 December 2020

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

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12 December 2020

Decreased hephaestin activity in the intestine of copper-deficient mice causes systemic iron deficiency

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12 December 2020

Inhibition of iron transport across human intestinal epithelial cells by hepcidin

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12 December 2020

Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1

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12 December 2020

Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element

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12 December 2020

An iron-regulated ferric reductase associated with the absorption of dietary iron

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12 December 2020

Duodenal cytochrome b and hephaestin expression in patients with iron deficiency and hemochromatosis

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12 December 2020

Serum transferrin receptor as a new index of erythropoiesis

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12 December 2020

Duodenal nonheme iron content correlates with iron stores in mice, but the relationship is altered by Hfe gene knock-out

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12 December 2020

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

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12 December 2020

IEC-6 cells are an appropriate model of intestinal iron absorption in rats

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12 December 2020

Mechanisms and regulation of intestinal iron absorption

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12 December 2020

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

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12 December 2020

The soluble transferrin receptor as a marker of iron homeostasis in normal subjects and in HFE-related hemochromatosis

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12 December 2020

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3

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12 December 2020

Adaptive changes of duodenal iron transport proteins in celiac disease.

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12 December 2020

Expression studies of neogenin and its ligand hemojuvelin in mouse tissues.

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12 December 2020

Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains

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12 December 2020

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

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12 December 2020

Transferrin receptor activity and localisation in the rat duodenum

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12 December 2020

Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis

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12 December 2020

mRNA expression of iron regulatory genes in β-thalassemia intermedia and β-thalassemia major mouse models

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12 December 2020

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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12 December 2020

Effect of hepcidin on intestinal iron absorption in mice.

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12 December 2020

Ferritin gene expression and transferrin receptor activity in intestine of rats with varying iron stores

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12 December 2020

Serum transferrin receptor as an index of iron absorption

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12 December 2020

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.

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12 December 2020

Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.

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12 December 2020

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

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12 December 2020

Dietary iron induces rapid changes in rat intestinal divalent metal transporter expression

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12 December 2020

Molecular regulation of hepatic expression of iron regulatory hormone hepcidin

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12 December 2020

Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice.

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12 December 2020

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

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12 December 2020

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

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12 December 2020

Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload

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12 December 2020

Duodenal Dcytb and hephaestin mRNA expression are not significantly modulated by variations in body iron homeostasis

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12 December 2020

Increased DMT1 but not IREG1 or HFE mRNA following iron depletion therapy in hereditary haemochromatosis

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12 December 2020

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

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12 December 2020

Duodenal expression of iron transport molecules in untreated haemochromatosis subjects.

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12 December 2020

Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

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12 December 2020

A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption.

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12 December 2020

The hemochromatosis protein HFE inhibits iron export from macrophages.

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12 December 2020

Neogenin mediates the action of repulsive guidance molecule

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12 December 2020

Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)

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12 December 2020

The ferroportin disease

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12 December 2020

Iron Imports. VI. HFE and regulation of intestinal iron absorption

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12 December 2020

Iron-dependent regulation of the divalent metal ion transporter

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12 December 2020

Iron supplementation during infancy--effects on expression of iron transporters, iron absorption, and iron utilization in rat pups

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12 December 2020

Metabolic regulation of citrate and iron by aconitases: role of iron-sulfur cluster biogenesis

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12 December 2020

A mouse model of juvenile hemochromatosis

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12 December 2020

Ferroportin is expressed on the mucous granule membrane of a subpopulation of goblet cells in the duodenum of the rat

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12 December 2020

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

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12 December 2020

Iron regulatory proteins 1 and 2 in human monocytes, macrophages and duodenum: expression and regulation in hereditary hemochromatosis and iron deficiency

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12 December 2020

THE GASTROINTESTINAL TRACT AND IRON ABSORPTION

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12 December 2020

Iron overload in mice expressing HFE exclusively in the intestinal villi provides evidence that HFE regulates a functional cross-talk between crypt and villi enterocytes

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12 December 2020

The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression

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12 December 2020

Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis.

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12 December 2020

Systemic regulation of Hephaestin and Ireg1 revealed in studies of genetic and nutritional iron deficiency

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12 December 2020

Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availability

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12 December 2020

Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis

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12 December 2020

10.1007/S00424-007-0264-9

Identifiers

DOI

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16 August 2017

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