Class switch recombination: a comparison between mouse and human. (Q36769461)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17383538 AND SRC:MED&resulttype=core&format=json

27 December 2019

review article

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title

Class switch recombination: a comparison between mouse and human (English)

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27 December 2019

author

Qiang Pan-Hammarström

series ordinal

1

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27 December 2019

3

Lennart Hammarström

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27 December 2019

2

Yaofeng Zhao

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27 December 2019

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language of work or name

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1 January 2007

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27 December 2019

published in

Advances in Immunology

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27 December 2019

volume

93

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27 December 2019

page(s)

1-61

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Cell cycle checkpoint signaling through the ATM and ATR kinases

27 December 2019

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The 3' end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four gamma genes

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B Lymphocytes of Xeroderma Pigmentosum or Cockayne Syndrome Patients with Inherited Defects in Nucleotide Excision Repair Are Fully Capable of Somatic Hypermutation of Immunoglobulin Genes

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Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

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7 January 2021

Nibrin functions in Ig class-switch recombination

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7 January 2021

Characterization of the enhancer region for germline transcription of the gamma 3 constant region gene of human immunoglobulin

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7 January 2021

Initial sequencing and analysis of the human genome

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7 January 2021

The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung(-/-)msh2(-/-) mice

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7 January 2021

MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification

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HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: evidence for specific promoter-enhancer interactions

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B cell development leads off with a base hit: dU:dG mismatches in class switching and hypermutation

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7 January 2021

Clinical spectrum of X-linked hyper-IgM syndrome

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7 January 2021

Rad51 expression and localization in B cells carrying out class switch recombination

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7 January 2021

Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching

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7 January 2021

The generation of antibody diversity through somatic hypermutation and class switch recombination

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A role for Mlh3 in somatic hypermutation

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Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

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The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination

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1 reference

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7 January 2021

CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Clinical and molecular analysis of patients with defects in micro heavy chain gene.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Delineation of the role of the Mre11 complex in class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

IgA production without mu or delta chain expression in developing B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Parallel adaptive radiations in two major clades of placental mammals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Sequences of human immunoglobulin switch regions: implications for recombination and transcription

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Enhancer Complexes Located Downstream of Both Human Immunoglobulin Cα Genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

IgG subclasses: Development of the serum concentrations in “normal” infants and children

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Molecular phylogenetics and the origins of placental mammals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Negative regulation of activation-induced cytidine deaminase in B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Transcription-coupled events associating with immunoglobulin switch region chromatin

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The human I alpha 1 and I alpha 2 germline promoter elements: proximal positive and distal negative elements may regulate the tissue specific expression of C alpha 1 and C alpha 2 germline transcripts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Structure of TGF-β1-induced human immunoglobulin Cα1 and Cα2 germ-line transcripts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The human I alpha 1 region contains a TGF-beta 1 responsive enhancer and a putative recombination hotspot

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The AID enzyme induces class switch recombination in fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

IgG subclass levels in infancy and childhood

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Structural analysis of human γ3 intervening regions and switch regions: Implication for the low frequency of switching in IgG3‐deficient patients

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Regulation of switching and production of IgA in human B cells in donors with duplicated alpha1 genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Lack of IgA in C(mu)-deficient patients

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Alternative end joining during switch recombination in patients with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Lack of association between human switch recombination breakpoints and the secondary structure of targeted DNA regions.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Signaling in B cells via Toll-like receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Sensing of intermediates in V(D)J recombination by ATM.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

RAG-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Identification of a homolog of the Cα3′/hs3 enhancer and of an allelic variant of the 3′IgH/hs1,2 enhancer downstream the human immunoglobulin α1 gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Duplications and deletions of the human IGHC locus: evolutionary implications

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

ATM is required for efficient recombination between immunoglobulin switch regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Humoral immune responses in CD40 ligand-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Extended nucleotide sequence of the switch region of the murine gene encoding immunoglobulin E.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

1 reference

7 January 2021

The role of APRIL and BAFF in lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Inducible DNA breaks in Ig S regions are dependent on AID and UNG

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

DNA polymerases and somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

NF-kappa B and Oct-2 synergize to activate the human 3' Igh hs4 enhancer in B cells.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Comparative analysis of human and mouse 3' Igh regulatory regions identifies distinctive structural features

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

ATM and ATR: networking cellular responses to DNA damage

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Normal immunoglobulin gene somatic hypermutation in Pol kappa-Pol iota double-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Production of sterile transcripts of C gamma genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Sequencing of selected regions of the human immunoglobulin heavy-chain gene locus that completes the sequence from JH through the delta constant region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Simple Method of Subtyping Human G-Myeloma Proteins based on Sensitivity to Pepsin Digestion

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Regulation of the T-independent humoral response by TACI

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Circular DNA is a product of the immunoglobulin class switch rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

AID-dependent histone acetylation is detected in immunoglobulin S regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Regulation of the germline immunoglobulin Cgamma1 promoter by CD40 ligand and IL-4: dual role for tandem NF-kappaB binding sites

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Initial sequencing and comparative analysis of the mouse genome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Mouse models for human DNA mismatch-repair gene defects

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A murine model of Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The repair and recombination enzyme ERCC1 is not required for immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Switch recombination breakpoints are strictly correlated with DNA recognition motifs for immunoglobulin S gamma 3 DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

AML and Ets proteins regulate the I alpha1 germ-line promoter

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Mice deficient for the CD40 ligand

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Activation and accumulation of B cells in TACI-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The role of polymerase eta in somatic hypermutation determined by analysis of mutations in a patient with xeroderma pigmentosum variant

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Mutations in the mu heavy-chain gene in patients with agammaglobulinemia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

V(D)J rearrangement in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Induction of IgG2a class switching in B cells by IL-27.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Influence of switch region length on immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

NF-kappaB/p50 and NF-kappaB/c-Rel differentially regulate the activity of the 3'alphaE-hsl,2 enhancer in normal murine B cells in an activation-dependent manner

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

A transforming growth factor beta-induced Smad3/Smad4 complex directly activates protein kinase A

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Identification of the activation-induced cytidine deaminase gene from zebrafish: an evolutionary analysis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: implication of CD45 as a Janus kinase phosphatase in antibody diversification

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(06)93001-6

7 January 2021

10.1016/S0065-2776(06)93001-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17383538 AND SRC:MED&resulttype=core&format=json

release_hbsga2ft2je77mtfwly3douxqa

27 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hbsga2ft2je77mtfwly3douxqa

24 November 2022

mapped directly with Wikidata item

1 reference