CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease. (Q36742266)

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9 January 2020

title

CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease (English)

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9 January 2020

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5

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9 January 2020

Lars Lewejohann

13

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9 January 2020

2

Richard Dodel

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9 January 2020

1

Michael Bacher

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9 January 2020

11

Jens Klotsche

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9 January 2020

author name string

Bayan Aljabari

3

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9 January 2020

Kathy Keyvani

4

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9 January 2020

Rakez Kayed

6

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9 January 2020

Charles Glabe

7

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9 January 2020

Nicole Goertz

8

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9 January 2020

Anne Hoppmann

9

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9 January 2020

Norbert Sachser

10

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9 January 2020

Susanne Schnell

12

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9 January 2020

Yousef Al-Abed

14

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9 January 2020

language of work or name

English

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publication date

23 June 2008

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Journal of Experimental Medicine

9 January 2020

published in

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9 January 2020

volume

205

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9 January 2020

issue

7

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9 January 2020

page(s)

1593-1599

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Fill My Datebook: a software tool to generate and handle lists of events

9 January 2020

cites work

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Alzheimer's disease is a synaptic failure

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

29 September 2017

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Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

29 September 2017

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Inflammation and Alzheimer's disease

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

29 September 2017

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

29 September 2017

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Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent

29 September 2017

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Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia

29 September 2017

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

29 September 2017

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Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone

29 September 2017

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An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality

29 September 2017

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Surface properties of bacillus Calmette-Guérin-activated mouse macrophages. Reduced expression of mannose-specific endocytosis, Fc receptors, and antigen F4/80 accompanies induction of Ia.

29 September 2017

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A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

29 September 2017

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Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat

29 September 2017

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Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

29 September 2017

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The role of A beta 42 in Alzheimer's disease

28 June 2018

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Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy

28 June 2018

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28 June 2018

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A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

28 June 2018

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The balance between approach and avoidance behaviors in a novel object exploration paradigm in mice

21 January 2018

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

21 January 2018

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Detailed analysis of the behavior of Lister and Wistar rats in anxiety, object recognition and object location tasks.

21 January 2018

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Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer's disease.

21 January 2018

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Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

5 September 2018

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Anti-inflammatory effects of a new tumour necrosis factor-alpha (TNF-alpha) inhibitor (CNI-1493) in collagen-induced arthritis (CIA) in rats

5 September 2018

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21 January 2018

Identifiers

DOI

10.1084/JEM.20060467

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18573905 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18573905 AND SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

18573905

1 reference