PARP inhibition selectively increases sensitivity to cisplatin in ERCC1-low non-small cell lung cancer cells. (Q36740692)

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21 February 2020

title

PARP inhibition selectively increases sensitivity to cisplatin in ERCC1-low non-small cell lung cancer cells (English)

1 reference

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non-small-cell lung carcinoma

21 February 2020

main subject

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1 reference

4

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21 February 2020

author name string

Haiying Cheng

1

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21 February 2020

Zhenfeng Zhang

2

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21 February 2020

Alain Borczuk

3

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21 February 2020

Adayabalam S Balajee

5

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21 February 2020

Howard B Lieberman

6

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21 February 2020

Balazs Halmos

7

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21 February 2020

language of work or name

English

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publication date

28 December 2012

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21 February 2020

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21 February 2020

volume

34

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21 February 2020

issue

4

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21 February 2020

page(s)

739-749

1 reference

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DNA damage-induced cell death: from specific DNA lesions to the DNA damage response and apoptosis

21 February 2020

cites work

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The knock-down of ERCC1 but not of XPF causes multinucleation

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Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas

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Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.

29 September 2017

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Drug Inhibition Profile Prediction for NFκB Pathway in Multiple Myeloma

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MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers

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CCT241533 Is a Potent and Selective Inhibitor of CHK2 that Potentiates the Cytotoxicity of PARP Inhibitors

29 September 2017

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The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

29 September 2017

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Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs

29 September 2017

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

29 September 2017

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

29 September 2017

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PARP inhibition: PARP1 and beyond

29 September 2017

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Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells

29 September 2017

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The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways

29 September 2017

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The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links

29 September 2017

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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

29 September 2017

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Cisplatin sensitivity is related to late DNA damage processing and checkpoint control rather than to the early DNA damage response.

29 September 2017

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

29 September 2017

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Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression

29 September 2017

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Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links

29 September 2017

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BRCA1: a new genomic marker for non-small-cell lung cancer

29 September 2017

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29 September 2017

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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

29 September 2017

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A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Small interfering RNA-induced suppression of ERCC1 enhances sensitivity of human cancer cells to cisplatin.

29 September 2017

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29 September 2017

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29 September 2017

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Influence of cis-diamminedichloroplatinum(II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient Chinese hamster ovary cells.

29 September 2017

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Cisplatin sensitivity/resistance in UV repair-deficient Chinese hamster ovary cells of complementation groups 1 and 3.

29 September 2017

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Association of epidermal growth factor receptor activating mutations with low ERCC1 gene expression in non-small cell lung cancer

28 June 2018

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Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks

5 September 2018

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Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

5 September 2018

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(ADP-ribose)n participates in DNA excision repair

21 January 2018

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Customizing Cisplatin Based on Quantitative Excision Repair Cross-Complementing 1 mRNA Expression: A Phase III Trial in Non–Small-Cell Lung Cancer

21 January 2018

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Iniparib in metastatic triple-negative breast cancer

21 January 2018

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12 December 2020

PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer

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12 December 2020

Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses

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12 December 2020

A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity

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12 December 2020

The platinum-based treatments for advanced non-small cell lung cancer, is low/negative ERCC1 expression better than high/positive ERCC1 expression? A meta-analysis

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Identifiers

DOI

10.1093/CARCIN/BGS393

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23275151 AND SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23275151 AND SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

23275151

1 reference