Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1. (Q36711639)

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scientific article published on December 2000

Language	Label	Description	Also known as
English	Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1.	scientific article published on December 2000

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1 (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

author name string

Jourdan M

1

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3 November 2019

Mechti N

3

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3 November 2019

Klein B

4

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3 November 2019

publication date

1 December 2000

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3 November 2019

Cell Death & Differentiation

1 reference

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3 November 2019

7

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3 November 2019

12

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3 November 2019

1244-1252

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

Insulin-like growth factor induces the survival and proliferation of myeloma cells through an interleukin-6-independent transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

IL-6 up-regulates mcl-1 in human myeloma cells through JAK / STAT rather than ras / MAP kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Interferon-alpha protects myeloma cell lines from dexamethasone-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Mcl-1 in transgenic mice promotes survival in a spectrum of hematopoietic cell types and immortalization in the myeloid lineage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

BCL-X expression in multiple myeloma: possible indicator of chemoresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Insulin-like growth factor I is a growth and survival factor in human multiple myeloma cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Growth regulatory pathways in myeloma. Evidence for autocrine oncostatin M expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Oncostatin M, leukemia inhibitory factor, and interleukin 6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

30 September 2017

Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Humoral Immunity Due to Long-Lived Plasma Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Bcl-2 tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Value of beta 2-microglobulin level and plasma cell labeling indices as prognostic factors in patients with newly diagnosed myeloma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Normal and neoplastic human plasma cells express bcl-2 antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

28 June 2018

Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

5 September 2018

Reversal of Blimp-1-mediated apoptosis by A1, a member of the Bcl-2 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

5 September 2018

Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

5 September 2018

Expression of Bcl-2 family of proteins in fresh myeloma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

5 September 2018

The myeloma cell antigen syndecan‐1 is lost by apoptotic myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

5 September 2018

Multiple myeloma cells are protected against dexamethasone-induced apoptosis by insulin-like growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423422

5 September 2018

Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth kinetics of plasma cell myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of JAK-TYK kinases in malignant plasma cell lines growth-stimulated by interleukins 6 and 11

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 inhibits apoptosis of malignant plasma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-xL

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 protein expression is not related to short survival in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the Bcl-2 homologue Mcl-1 correlates with survival of peripheral blood B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11175262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.CDD.4400758

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175262 AND SRC:MED&resulttype=core&format=json

3 November 2019

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