Activating and inhibitory functions of DAP12. (Q36707206)

15 August 2017

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title

Activating and inhibitory functions of DAP12. (English)

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15 August 2017

Marco Colonna

2

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author name string

Isaiah R Turnbull

series ordinal

1

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15 August 2017

publication date

15 January 2007

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Nature Reviews Immunology

15 August 2017

published in

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15 August 2017

volume

7

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15 August 2017

issue

2

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15 August 2017

page(s)

155-161

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Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes

15 August 2017

cites work

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Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

21 January 2018

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Cutting Edge: TREM-2 Attenuates Macrophage Activation

21 January 2018

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Syk regulation of phosphoinositide 3-kinase-dependent NK cell function

21 January 2018

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Intracellular signaling by the killer immunoglobulin-like receptors and Ly49.

21 January 2018

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Recognition of a virus-encoded ligand by a natural killer cell activation receptor

21 January 2018

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DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection

21 January 2018

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Pattern recognition by TREM-2: binding of anionic ligands

21 January 2018

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Class I MHC-binding characteristics of the 129/J Ly49 repertoire

21 January 2018

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Cutting edge: signal-regulatory protein beta 1 is a DAP12-associated activating receptor expressed in myeloid cells

21 January 2018

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Molecular characterization of a novel immune receptor restricted to the monocytic lineage

21 January 2018

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Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.

21 January 2018

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Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

21 January 2018

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Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family

31 March 2020

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Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17

31 March 2020

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A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

31 March 2020

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TREM-1 amplifies inflammation and is a crucial mediator of septic shock

31 March 2020

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Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

31 March 2020

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A cell-surface molecule selectively expressed on murine natural interferon-producing cells that blocks secretion of interferon-alpha

31 March 2020

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Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44.

31 March 2020

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The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site

31 March 2020

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Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H

31 March 2020

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Association of DAP12 with activating CD94/NKG2C NK cell receptors

31 March 2020

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Multiplicity and plasticity of natural killer cell signaling pathways

31 March 2020

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Natural killer cell signaling pathways

31 March 2020

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DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase

31 March 2020

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

31 March 2020

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The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function

31 March 2020

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NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis

31 March 2020

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Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity

31 March 2020

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Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors

31 March 2020

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Pivotal role of KARAP/DAP12 adaptor molecule in the natural killer cell-mediated resistance to murine cytomegalovirus infection

31 March 2020

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Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice

31 March 2020

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Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells

31 March 2020

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A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis

31 March 2020

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DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis

31 March 2020

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TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

31 March 2020

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Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

31 March 2020

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Impaired differentiation of osteoclasts in TREM-2-deficient individuals

31 March 2020

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DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

31 March 2020

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Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

31 March 2020

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Sampling and signaling in plasmacytoid dendritic cells: the potential roles of Siglec-H.

31 March 2020

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Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

31 March 2020

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The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

31 March 2020

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Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling

31 March 2020

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SHP-1 inhibits LPS-mediated TNF and iNOS production in murine macrophages.

31 March 2020

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PI3K and negative regulation of TLR signaling.

31 March 2020

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PI3K-mediated negative feedback regulation of IL-12 production in DCs

31 March 2020

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The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

31 March 2020

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

31 March 2020

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Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

31 March 2020

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

31 March 2020

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

31 March 2020

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Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

31 March 2020

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Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

31 March 2020

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Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.

31 March 2020

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U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7.

31 March 2020

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Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture

31 March 2020

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NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation

31 March 2020

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Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D

31 March 2020

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Association of signal-regulatory proteins beta with KARAP/DAP-12

31 March 2020

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Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells

31 March 2020

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PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif-bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta

31 March 2020

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Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2014

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15 August 2017

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