The transmembrane protein 16A Ca(2 )-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness (Q36702774)

15 August 2017

The transmembrane protein 16A Ca(2 )-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness (English)

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15 August 2017

transmembrane protein

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4

Lawrence M Lifshitz

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15 August 2017

Cheng-Hai Zhang

1

1 reference

15 August 2017

Yinchuan Li

2

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15 August 2017

Wei Zhao

3

1 reference

15 August 2017

Hequan Li

5

1 reference

15 August 2017

Brian D Harfe

6

1 reference

15 August 2017

Min-Sheng Zhu

7

1 reference

15 August 2017

Ronghua ZhuGe

8

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15 August 2017

language of work or name

English

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publication date

13 December 2012

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American Journal of Respiratory and Critical Care Medicine

15 August 2017

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15 August 2017

187

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15 August 2017

4

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15 August 2017

374-381

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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Myosin light chain kinase is necessary for tonic airway smooth muscle contraction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Studies on expression and function of the TMEM16A calcium-activated chloride channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Ca2 sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Noninflammatory mechanisms of airway hyper-responsiveness in bronchial asthma: an overview.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

TMEM16A confers receptor-activated calcium-dependent chloride conductance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

A close association of RyRs with highly dense clusters of Ca2 -activated Cl- channels underlies the activation of STICs by Ca2 sparks in mouse airway smooth muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

The transmembrane protein TMEM16A is required for normal development of the murine trachea

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

GABAA receptors are expressed and facilitate relaxation in airway smooth muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Airway smooth muscle in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Increased lungkine and chitinase levels in allergic airway inflammation: a proteomics approach

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

hCLCA1 and mCLCA3 are secreted non-integral membrane proteins and therefore are not ion channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Pharmacological modulation of sarcoplasmic reticulum function in smooth muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Association of the hCLCA1 gene with childhood and adult asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Increased expression of the human Ca2 -activated Cl- channel 1 (CaCC1) gene in the asthmatic airway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Ca2 sparks activate K and Cl- channels, resulting in spontaneous transient currents in guinea-pig tracheal myocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Characteristics and physiological role of the Ca(2 )-activated Cl- conductance in smooth muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

mCLCA3 does not contribute to calcium-activated chloride conductance in murine airways.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

The Cl(-) channel blocker niflumic acid releases Ca(2 ) from an intracellular store in rat pulmonary artery smooth muscle cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Acetylcholine activates non-selective cation and chloride conductances in canine and guinea-pig tracheal myocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Modulation of the allergic asthma transcriptome following resiquimod treatment.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Transmembrane protein 16A (TMEM16A) is a Ca2 -regulated Cl- secretory channel in mouse airways

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Adenovirus IL-13-induced airway disease in mice: a corticosteroid-resistant model of severe asthma.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

The asthma channel? Stay tuned . . .

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Niflumic acid suppresses interleukin-13-induced asthma phenotypes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Gob-5 is not essential for mucus overproduction in preclinical murine models of allergic asthma

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Differential regulation of Ca(2 )-activated Cl(-) currents in rabbit arterial and portal vein smooth muscle cells by Ca(2 )-calmodulin-dependent kinase

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Neurokinin A and Ca2 current induce Ca(2 )-activated Cl(-) currents in guinea-pig tracheal myocytes

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acids

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Niflumic acid inhibits goblet cell degranulation in a guinea pig asthma model

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3603598

Histamine activates Cl- and K currents in guinea-pig tracheal myocytes: convergence with muscarinic signalling pathway

20 October 2018

1 reference

12 December 2020

Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels

1 reference

12 December 2020

Spontaneous transient inward currents and rhythmicity in canine and guinea-pig tracheal smooth muscle cells

1 reference

12 December 2020

Ca(2 )-dependent Cl- current in canine tracheal smooth muscle cells

1 reference

12 December 2020

Ionic mechanisms underlying electrical slow waves in canine airway smooth muscle

1 reference

12 December 2020

Activation of BK channels may not be required for bitter tastant-induced bronchodilation

1 reference

12 December 2020

Calcium release and calcium-activated chloride channels in airway smooth muscle cells

1 reference

12 December 2020

Effects of paxilline on K channels in rat mesenteric arterial cells

1 reference

12 December 2020

Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.

1 reference

12 December 2020

10.1164/RCCM.201207-1303OC

Identifiers

DOI

1 reference

15 August 2017

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15 August 2017

PubMed publication ID

23239156

1 reference