Transduction of brain by herpes simplex virus vectors (Q36681937)

15 August 2017

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title

Transduction of brain by herpes simplex virus vectors (English)

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15 August 2017

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1

Bradford K Berges

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15 August 2017

John H Wolfe

2

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15 August 2017

Nigel W Fraser

series ordinal

3

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15 August 2017

publication date

1 January 2007

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15 August 2017

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15 August 2017

volume

15

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15 August 2017

issue

1

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15 August 2017

page(s)

20-29

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Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain

15 August 2017

cites work

1 reference

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7 January 2021

Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice

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7 January 2021

Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors.

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7 January 2021

Elimination of lysosomal storage in brains of MPS VII mice treated by intrathecal administration of an adeno-associated virus vector

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7 January 2021

Enhanced secretion and uptake of beta-glucuronidase improves adeno-associated viral-mediated gene therapy of mucopolysaccharidosis type VII mice

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7 January 2021

Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII.

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7 January 2021

Distribution of a lysosomal enzyme in the adult brain by axonal transport and by cells of the rostral migratory stream.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Reversal of pathology in the entire brain of mucopolysaccharidosis type VII mice after lentivirus-mediated gene transfer.

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7 January 2021

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors

1 reference

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7 January 2021

Intraventricular brain injection of adeno-associated virus type 1 (AAV1) in neonatal mice results in complementary patterns of neuronal transduction to AAV2 and total long-term correction of storage lesions in the brains of beta-glucuronidase-defici

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

The blood-brain barrier: bottleneck in brain drug development

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https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery

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https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

AAV vector-mediated correction of brain pathology in a mouse model of Niemann-Pick A disease

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Adeno-associated virus vector-mediated transduction in the cat brain

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Molecular pathophysiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Gene therapy for lysosomal storage diseases: the lessons and promise of animal models

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Surface properties, more than size, limiting convective distribution of virus-sized particles and viruses in the central nervous system

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Adenovirus-mediated gene transfer to the brain: methodological assessment

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Targeting specific neuronal populations using adeno- and lentiviral vectors: applications for imaging and studies of cell function.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Adeno-associated virus (AAV) vectors in the CNS.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Herpes vector-mediated gene transfer in treatment of diseases of the nervous system

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Update on adenovirus and its vectors

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Retroviral vectors: new applications for an old tool

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Integration of adeno-associated virus (AAV) and recombinant AAV vectors

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Widespread gene delivery and structure-specific patterns of expression in the brain after intraventricular injections of neonatal mice with an adeno-associated virus vector

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Retrograde transfer of replication deficient recombinant adenovirus vector in the central nervous system for tracing studies

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Targeted retrograde gene delivery for neuronal protection

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Intraneural colchicine inhibition of adenoviral and adeno-associated viral vector remote spinal cord gene delivery

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Targeting functional subtypes of spinal motoneurons and skeletal muscle fibers in vivo by intramuscular injection of adenoviral and adeno-associated viral vectors

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Transfer of a foreign gene into the brain using adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Spread of herpes simplex virus in peripheral nerves

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

The neuronal host cell factor-binding protein Zhangfei inhibits herpes simplex virus replication

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Microtubule polarity in the peripheral processes of trigeminal ganglion cells: relevance for the retrograde transport of herpes simplex virus.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Sorting and transport of alpha herpesviruses in axons

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Infection and spread of alphaherpesviruses in the nervous system

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

HSV-1-derived recombinant and amplicon vectors for gene transfer and gene therapy

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

PROPERTIES OF DEOXYTHYMIDINE KINASE PARTIALLY PURIFIED FROM NONINFECTED MOUSE FIBROBLAST CELLS

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Molecular Genetics of Herpes Simplex Virus II. Mapping of the Major Viral Glycoproteins and of the Genetic Loci Specifying the Social Behavior of Infected Cells

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Herpes simplex virus vectors for the nervous system

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Stable levels of long-term transgene expression driven by the latency-associated transcript promoter in a herpes simplex virus type 1 vector

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Latency associated promoter transgene expression in the central nervous system after stereotaxic delivery of replication-defective HSV-1-based vectors

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Herpes simplex type 1 DNA in human brain tissue

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Prevalence and distribution of HSV-1, VZV, and HHV-6 in human cranial nerve nuclei III, IV, VI, VII, and XII.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Selective vulnerability of mouse CNS neurons to latent infection with a neuroattenuated herpes simplex virus-1.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Utilization of the herpes simplex virus type 1 latency-associated regulatory region to drive stable reporter gene expression in the nervous system.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Expression of the lacZ reporter gene in the rat basal forebrain, hippocampus, and nigrostriatal pathway using a nonreplicating herpes simplex vector

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Potential and limitations of a gamma 34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

A herpesvirus vector can transduce axotomized brain neurons

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

A live non-neurovirulent herpes simplex virus vector expresses beta-galactosidase in the nervous system of the Wistar and Sprague-Dawley strain rat for a prolonged period

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Expression from the herpes simplex virus type 1 latency-associated promoter in the murine central nervous system

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Herpesvirus vector gene transfer and expression of beta-glucuronidase in the central nervous system of MPS VII mice

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Specific Patterns of Defective HSV-1 Gene Transfer in the Adult Central Nervous System: Implications for Gene Targeting

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Significantly increased expression of beta-glucuronidase in the central nervous system of mucopolysaccharidosis type VII mice from the latency-associated transcript promoter in a nonpathogenic herpes simplex virus type 1 vector

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Enhanced reporter gene expression in the rat brain from helper virus-free HSV-1 vectors packaged in the presence of specific mutated HSV-1 proteins that affect the virion

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Spread and replication of and immune response to gamma134.5-negative herpes simplex virus type 1 vectors in BALB/c mice

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: A light and electron microscopic study

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Pathways of viral gene expression during acute neuronal infection with HSV-1

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Decreased reporter gene expression during latent infection with HSV LAT promoter constructs.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Long-term transgene expression in mice infected with a herpes simplex virus type 1 mutant severely impaired for immediate-early gene expression

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Direction of transneuronal transport of herpes simplex virus 1 in the primate motor system is strain-dependent

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Ultrastructural and immunoperoxidase study of striatonigral neurons by means of retrograde axonal transport of herpes simplex virus

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

A herpes simplex virus type 1 vector as marker for retrograde neuronal tracing: characterization of lacZ transcription and localization of labelled neuronal cells in sensory and autonomic ganglia after inoculation of the anterior segment of the eye.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

beta-Gal enzyme activity driven by the HSV LAT promoter does not correspond to beta-gal RNA levels in mouse trigeminal ganglia.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Heparan sulfate proteoglycan binding by herpes simplex virus type 1 glycoproteins B and C, which differ in their contributions to virus attachment, penetration, and cell-to-cell spread

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Pseudotyping of glycoprotein D-deficient herpes simplex virus type 1 with vesicular stomatitis virus glycoprotein G enables mutant virus attachment and entry

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Targeted gene transfer to nigrostriatal neurons in the rat brain by helper virus-free HSV-1 vector particles that contain either a chimeric HSV-1 glycoprotein C-GDNF or a gC-BDNF protein

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Comparative analysis of genomic HSV vectors for gene delivery to motor neurons following peripheral inoculation in vivo

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

HSV1 latency sites after inoculation in the lip: assessment of their localization and connections to the eye.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Laser-capture microdissection: refining estimates of the quantity and distribution of latent herpes simplex virus 1 and varicella-zoster virus DNA in human trigeminal Ganglia at the single-cell level

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behaviora

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Long-term expression of a reporter gene from latent herpes simplex virus in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Lentiviral gene transfer to the nonhuman primate brain

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Effective gene therapy for an inherited CNS disease in a large animal model

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Golgi-like, transneuronal retrograde labelling with CNS injections of herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Input to the primate frontal eye field from the substantia nigra, superior colliculus, and dentate nucleus demonstrated by transneuronal transport

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Infection and establishment of latency in the dog brain after direct inoculation of a nonpathogenic strain of herpes simplex virus-1.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Prevalence of lysosomal storage disorders

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Lysosomal storage disorders

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Hurler and Hunter syndromes: mutual correction of the defect in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Sanfilippo disease type B: enzyme replacement and metabolic correction in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

In vitro correction of deficient human fibroblasts by beta-glucuronidase from different human sources

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Intravitreal gene therapy reduces lysosomal storage in specific areas of the CNS in mucopolysaccharidosis VII mice.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Axons mediate the distribution of arylsulfatase A within the mouse hippocampus upon gene delivery.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

AAV2-mediated ocular gene therapy for infantile neuronal ceroid lipofuscinosis.

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Blood-brain barrier drug targeting: the future of brain drug development

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Use of herpes virus amplicon vectors to study brain disorders

1 reference

https://api.crossref.org/works/10.1038/SJ.MT.6300018

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300018

1 reference

15 August 2017

1 reference