c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. (Q36671497)

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20 December 2019

title

c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis (English)

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20 December 2019

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1

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20 December 2019

John M Mariadason

2

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20 December 2019

Courtney Nicholas

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20 December 2019

author name string

A J Wilson

3

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20 December 2019

W Yang

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20 December 2019

G A Corner

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20 December 2019

M J Aranes

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20 December 2019

L H Augenlicht

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20 December 2019

language of work or name

English

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publication date

1 November 2003

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British Journal of Cancer

20 December 2019

published in

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20 December 2019

volume

89

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20 December 2019

issue

9

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20 December 2019

page(s)

1757-1765

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Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells.

20 December 2019

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Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin.

30 September 2017

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Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

30 September 2017

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ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy

30 September 2017

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c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo.

30 September 2017

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Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.

30 September 2017

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Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

30 September 2017

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30 September 2017

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

30 September 2017

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Mechanisms of apoptosis by c-Myc

30 September 2017

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

30 September 2017

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

30 September 2017

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Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells

30 September 2017

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

30 September 2017

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Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination

30 September 2017

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WAF1, a potential mediator of p53 tumor suppression

30 September 2017

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Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

30 September 2017

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Cloning of mid-G1 serum response genes and identification of a subset regulated by conditional myc expression

30 September 2017

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Deregulation of c-myc gene expression in human colon carcinoma is not accompanied by amplification or rearrangement of the gene

30 September 2017

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Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

30 September 2017

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Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate

30 September 2017

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Phase II study of daunorubicin in previously untreated patients with advanced colorectal carcinoma

30 September 2017

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Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells

30 September 2017

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Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene

28 June 2018

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c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif

28 June 2018

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A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer.

28 June 2018

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Cell culture of the mucinous variant of human colorectal carcinoma

28 June 2018

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Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping

28 June 2018

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A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer.

20 September 2018

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Glutathione S-transferase M1 and T1 null genotypes and the risk of gastric and colorectal cancers

20 September 2018

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Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

20 September 2018

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Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells.

20 September 2018

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Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

20 September 2018

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Crossref

https://api.crossref.org/works/10.1038/SJ.BJC.6601338

Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: a frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial

21 January 2018

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12 December 2020

Up-regulation of lysozyme production in colonic adenomas and adenocarcinomas

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12 December 2020

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

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12 December 2020

Deregulated BCL2 expression enhances growth of a human B cell line

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12 December 2020

Expression of MUC1 and MUC2 Mucins by Human Tumor Cell Lines

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6601338

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583781 AND SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583781 AND SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

14583781

1 reference