Targeted therapies in colorectal cancer-an integrative view by PPPM (Q36646911)

15 August 2017

1 reference

title

Targeted therapies in colorectal cancer-an integrative view by PPPM (English)

1 reference

15 August 2017

1 reference

Suzanne Hagan

1

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15 August 2017

Maria C M Orr

series ordinal

2

1 reference

15 August 2017

Brendan Doyle

series ordinal

3

1 reference

15 August 2017

28 January 2013

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15 August 2017

1 reference

15 August 2017

4

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15 August 2017

1

1 reference

15 August 2017

3

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Creative Commons Attribution 2.0 Generic

15 August 2017

start time

28 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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30 September 2017

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30 September 2017

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21 January 2018

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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A small step towards personalized medicine for non-small cell lung cancer

30 September 2017

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KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer.

30 September 2017

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Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer.

30 September 2017

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30 September 2017

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Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer

30 September 2017

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Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer

30 September 2017

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Skin toxicities associated with epidermal growth factor receptor inhibitors

30 September 2017

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Microsatellite instability does not predict the efficacy of chemotherapy in metastatic colorectal cancer. A systematic review and meta-analysis.

30 September 2017

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Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

30 September 2017

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PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies

30 September 2017

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Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function

30 September 2017

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American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy

30 September 2017

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Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer

30 September 2017

1 reference

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Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100.

30 September 2017

1 reference

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

30 September 2017

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An integrated genomic analysis of human glioblastoma multiforme

30 September 2017

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Modes of resistance to anti-angiogenic therapy

30 September 2017

1 reference

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Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.

30 September 2017

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Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study.

30 September 2017

1 reference

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Implications of EGFR PharmDx kit for cetuximab eligibility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms

30 September 2017

1 reference

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Association of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab.

30 September 2017

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Cetuximab for the treatment of colorectal cancer.

30 September 2017

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PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

30 September 2017

1 reference

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The genomic landscapes of human breast and colorectal cancers

30 September 2017

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Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer

30 September 2017

1 reference

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Sorafenib in advanced clear-cell renal-cell carcinoma

30 September 2017

1 reference

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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

30 September 2017

1 reference

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Classification of colorectal cancer based on correlation of clinical, morphological and molecular features

30 September 2017

1 reference

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Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines

30 September 2017

1 reference

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Recurrent KRAS codon 146 mutations in human colorectal cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Randomized phase III trial results of panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, in metastatic colorectal cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.

30 September 2017

1 reference

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Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

30 September 2017

1 reference

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K-ras mutations in patients with early colorectal cancers

30 September 2017

1 reference

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Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7

30 September 2017

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Genetic alterations during colorectal-tumor development

30 September 2017

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Correlation of bevacizumab-induced hypertension and outcome in the BOXER study, a phase II study of capecitabine, oxaliplatin (CAPOX) plus bevacizumab as peri-operative treatment in 45 patients with poor-risk colorectal liver-only metastases unsuita

30 September 2017

1 reference

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"First do no harm" and the importance of prediction in oncology.

28 June 2018

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Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer.

28 June 2018

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Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study

28 June 2018

1 reference

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Isolation of a tumor factor responsible for angiogenesis

28 June 2018

1 reference

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Gastrointestinal perforation associated with bevacizumab use in metastatic colorectal cancer: results from a large treatment observational cohort study

28 June 2018

1 reference

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Circulating endothelial cells and their apoptotic fraction are mutually independent predictive biomarkers in Bevacizumab-based treatment for advanced colorectal cancer.

20 September 2018

1 reference

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The Continuation of Bevacizumab Following Disease Progression in Patients with Metastatic Colorectal Cancer Offers a Survival Benefit

20 September 2018

1 reference

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Molecular morphometric analysis shows relative intra-tumoural homogeneity for KRAS mutations in colorectal cancer.

20 September 2018

1 reference

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Cost‐effectiveness of KRAS testing in metastatic colorectal cancer patients in the United States and Germany

20 September 2018

1 reference

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Circulating endothelial progenitors and CXCR4‐positive circulating endothelial cells are predictive markers for bevacizumab

20 September 2018

1 reference

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Clinical value of circulating endothelial cell levels in metastatic colorectal cancer patients treated with first-line chemotherapy and bevacizumab.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

KRAS and BRAF mutation analysis in metastatic colorectal cancer: a cost-effectiveness analysis from a Swiss perspective.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Biweekly cetuximab plus irinotecan as second-line chemotherapy for patients with irinotecan-refractory and KRAS wild-type metastatic colorectal cancer according to epidermal growth factor receptor expression status.

20 September 2018

1 reference

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Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.

20 September 2018

1 reference

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Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing.

20 September 2018

1 reference

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Characteristics of recurrence after curative resection for T1 colorectal cancer: Japanese multicenter study

20 September 2018

1 reference

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Managing cetuximab hypersensitivity-infusion reactions: incidence, risk factors, prevention, and retreatment

20 September 2018

1 reference

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Correlation of FCGR3A and EGFR germline polymorphisms with the efficacy of cetuximab in KRAS wild-type metastatic colorectal cancer.

20 September 2018

1 reference

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Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Coexpression of biological key modulators in primary colorectal carcinomas and related metastatic sites: implications for treatment with cetuximab

20 September 2018

1 reference

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Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

PTEN status in advanced colorectal cancer treated with cetuximab.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Hypertension and clinical benefit of bevacizumab in the treatment of advanced renal cell carcinoma

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

The importance of KRAS mutations and EGF61A>G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Arterial hypertension correlates with clinical outcome in colorectal cancer patients treated with first-line bevacizumab

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

A phase III randomized, open-label, controlled trial of chemotherapy and bevacizumab with or without panitumumab in the first-line treatment of patients with metastatic colorectal cancer.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584939

Screening for Colorectal Cancer

20 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186/1878-5085-4-3

Clinical impact of anti-epidermal growth factor receptor monoclonal antibodies in first-line treatment of metastatic colorectal cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186/1878-5085-4-3

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

21 January 2018

1 reference

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https://api.crossref.org/works/10.1186/1878-5085-4-3

Circulating endothelial cells predict for response to bevacizumab-based chemotherapy in metastatic colorectal cancer

21 January 2018

1 reference

12 December 2020

Skin rash secondary to bevacizumab in a patient with advanced colorectal cancer and relation to response

1 reference

12 December 2020

Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases

1 reference

12 December 2020

NICE guidance on cetuximab, bevacizumab, and panitumumab for treatment of metastatic colorectal cancer after first-line chemotherapy

1 reference

12 December 2020

Reasons for avoidance of bevacizumab with first-line FOLFOX for advanced colorectal cancer

1 reference

12 December 2020

Vascular endothelial growth factor polymorphisms and clinical outcome in colorectal cancer patients treated with irinotecan-based chemotherapy and bevacizumab

1 reference

12 December 2020

The predictive and prognostic value of circulating endothelial cells in advanced colorectal cancer patients receiving first-line chemotherapy and bevacizumab

1 reference

12 December 2020

Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer

1 reference

12 December 2020

Heterogeneous distribution of K-ras mutations in primary colon carcinomas: implications for EGFR-directed therapy

1 reference

12 December 2020

Molecular Genetics of Colorectal Cancer

1 reference

12 December 2020

Circulating endothelial cells and endothelial progenitors as predictive markers of clinical response to bevacizumab-based first-line treatment in advanced colorectal cancer patients

1 reference

12 December 2020

Concordant analysis of KRAS status in primary colon carcinoma and matched metastasis

1 reference

12 December 2020

Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO C

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12 December 2020

Identifiers

DOI

10.1186/1878-5085-4-3

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference

15 August 2017

PubMed publication ID

23356214

1 reference