Low SGK1 expression in human adrenocortical tumors is associated with ACTH-independent glucocorticoid secretion and poor prognosis. (Q36631392)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23055545 AND SRC:MED&resulttype=core&format=json

10 March 2020

title

Low SGK1 expression in human adrenocortical tumors is associated with ACTH-independent glucocorticoid secretion and poor prognosis (English)

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10 March 2020

1

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10 March 2020

Silviu Sbiera

series ordinal

2

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10 March 2020

7

Martin Fassnacht

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10 March 2020

8

Bruno Allolio

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10 March 2020

3

Ellen Leich

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10 March 2020

4

Frédérique Tissier

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10 March 2020

5

Sonja Steinhauer

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10 March 2020

6

Timo Deutschbein

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10 March 2020

language of work or name

English

0 references

publication date

9 October 2012

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The Journal of Clinical Endocrinology and Metabolism

10 March 2020

published in

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10 March 2020

volume

97

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10 March 2020

issue

12

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10 March 2020

page(s)

E2251-60

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Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways

10 March 2020

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Single nucleotide polymorphism microarray analysis in cortisol-secreting adrenocortical adenomas identifies new candidate genes and pathways

30 September 2017

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Notch inhibition as a promising new approach to cancer therapy

30 September 2017

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Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype

30 September 2017

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Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

30 September 2017

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The glucocorticoid receptor and its expression in the anterior pituitary and the adrenal cortex: a source of variation in hypothalamic-pituitary-adrenal axis function; implications for pituitary and adrenal tumors

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Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.

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Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase

30 September 2017

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Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation

30 September 2017

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Colorectal carcinoma cells--regulation of survival and growth by SGK1.

30 September 2017

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Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

30 September 2017

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The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

30 September 2017

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Clinical management of adrenocortical carcinoma

30 September 2017

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The role of Notch signaling in human cervical cancer: implications for solid tumors

30 September 2017

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The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline

30 September 2017

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Notch signaling in leukemias and lymphomas

30 September 2017

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Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum- and glucocorticoid-induced protein kinase and Akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor c

30 September 2017

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IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells

30 September 2017

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(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms

30 September 2017

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RECIST revisited: a review of validation studies on tumour assessment

30 September 2017

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Dual-specificity phosphatase 1 and serum/glucocorticoid-regulated kinase are downregulated in prostate cancer.

30 September 2017

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The clinically inapparent adrenal mass: update in diagnosis and management

30 September 2017

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A new mathematical model for relative quantification in real-time RT-PCR

30 September 2017

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Incidence and late prognosis of cushing's syndrome: a population-based study

30 September 2017

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Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

30 September 2017

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Expression of excision repair cross complementing group 1 and prognosis in adrenocortical carcinoma patients treated with platinum-based chemotherapy.

30 September 2017

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28 June 2018

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Improved survival in patients with stage II adrenocortical carcinoma followed up prospectively by specialized centers

20 September 2018

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Disrupted corticosterone pulsatile patterns attenuate responsiveness to glucocorticoid signaling in rat brain

20 September 2018

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20 September 2018

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SGK1, a potential regulator of c-fms related breast cancer aggressiveness

20 September 2018

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Incidence and Late Prognosis of Cushing’s Syndrome: A Population-Based Study1

20 September 2018

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[Arterial hypertension and subclinical Cushing's syndrome]

20 September 2018

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High Diagnostic and Prognostic Value of Steroidogenic Factor-1 Expression in Adrenal Tumors

21 October 2018

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Limited prognostic value of the 2004 International Union Against Cancer staging classification for adrenocortical carcinoma

4 December 2018

1 reference

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AKT Is Highly Phosphorylated in Pheochromocytomas But Not in Benign Adrenocortical Tumors

4 December 2018

1 reference

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β-catenin activation is associated with specific clinical and pathologic characteristics and a poor outcome in adrenocortical carcinoma

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23055545

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/JC.2012-2669

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23055545 AND SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23055545 AND SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23055545

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23055545 AND SRC:MED&resulttype=core&format=json