Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells (Q36593109)

15 August 2017

Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells (English)

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15 August 2017

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hepatocellular carcinoma

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4

Timothy J Garrett

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15 August 2017

Mei Zhao

1

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15 August 2017

Maria A Ralat

2

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15 August 2017

Vanessa da Silva

3

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15 August 2017

Stephan Melnyk

5

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15 August 2017

S Jill James

6

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15 August 2017

Jesse F Gregory

7

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15 August 2017

4 December 2012

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American Journal of Physiology - Endocrinology and Metabolism

15 August 2017

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15 August 2017

304

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15 August 2017

4

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15 August 2017

E342-51

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Marginal vitamin B-6 deficiency decreases plasma (n-3) and (n-6) PUFA concentrations in healthy men and women

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

PLP‐dependent enzymes as entry and exit gates of sphingolipid metabolism

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Fatty acid elongases in mammals: their regulation and roles in metabolism

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

A simplified method for analysis of polyunsaturated fatty acids

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

A simple method for the isolation and purification of total lipides from animal tissues

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC Group

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Alteration in the phosphatidylcholine biosynthesis of rat liver microsomes caused by vitamin B6 deficiency

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Carnitine biosynthesis. beta-Hydroxylation of trimethyllysine by an alpha-ketoglutarate-dependent mitochondrial dioxygenase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Regulatory Function of Δ6 Desaturase — Key Enzyme of Polyunsaturated Fatty Acid Synthesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Folate deprivation reduces homocysteine remethylation in a human intestinal epithelial cell culture model: role of serine in one-carbon donation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Lipid balance in HepG2 cells: active synthesis and impaired mobilization.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Fatty acid uptake and metabolism in Hep G2 human-hepatoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

A study of the chemical nature of vitamin B(6) and methods for its preparation in a concentrated state

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

New insights into lipid and fatty acid metabolism via stable isotopes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Electroencephalographic and Nerve-Conduction Studies in Experimental Vitamin B6, Deficiency in Adults

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Triglyceride Metabolism in Pyridoxine-deficient Rats

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Delta-6-desaturase activity of human liver microsomes from patients with different types of liver injury

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

In vivo evidence for a vitamin B-6 requirement in carnitine synthesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Electroencephalographic changes and periodontal status during short-term vitamin B-6 depletion of young, nonpregnant women

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Plasma glutathione and cystathionine concentrations are elevated but cysteine flux is unchanged by dietary vitamin B-6 restriction in young men and women

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Preparation of fatty acid methyl esters for gas-chromatographic analysis of marine lipids: insight studies.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Low Vitamin B6 but Not Homocyst(e)ine Is Associated With Increased Risk of Stroke and Transient Ischemic Attack in the Era of Folic Acid Grain Fortification

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566509

Folate and Vitamin B 6 From Diet and Supplements in Relation to Risk of Coronary Heart Disease Among Women

20 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1152/AJPENDO.00359.2012

Low Plasma Vitamin B-6 Status Affects Metabolism through the Kynurenine Pathway in Cardiovascular Patients with Systemic Inflammation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1152/AJPENDO.00359.2012

Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectoris

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1152/AJPENDO.00359.2012

Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study

21 January 2018

1 reference

12 December 2020

Effect of Vitamin B6 Deficiency on Tissue Dehydrogenases and Fat Synthesis in Rats

1 reference

12 December 2020

Effects of vitamin B-6 on (n-3) polyunsaturated fatty acid metabolism

1 reference

12 December 2020

Delta6- and delta5-desaturase activities in the human fetal liver: kinetic aspects

1 reference

12 December 2020

Effect of pyridoxine deficiency on phospholipid methylation in rat liver microsomes

1 reference

12 December 2020

The Effect of Vitamin B-6 Deficiency on the Fatty Acid Composition of the Major Phospholipids in the Rat

1 reference

12 December 2020

Accumulation of linoleic and gamma-linolenic acids in tissue lipids of pyridoxine-deficient rats

1 reference

12 December 2020

Dual influence of aging and vitamin B6 deficiency on delta-6-desaturation of essential fatty acids in rat liver microsomes

1 reference

12 December 2020

Stability of pyridoxal-5-phosphate semicarbazone: applications in plasma vitamin B6 analysis and population surveys of vitamin B6 nutritional status

1 reference

12 December 2020

Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations

1 reference

12 December 2020

10.1152/AJPENDO.00359.2012

Identifiers

DOI

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15 August 2017

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15 August 2017

PubMed publication ID

23211517

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