Translational approaches using metastasis suppressor genes (Q36582342)

15 August 2017

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title

Translational approaches using metastasis suppressor genes (English)

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15 August 2017

5

Patricia S Steeg

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15 August 2017

Diane Palmieri

1

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15 August 2017

Christine E Horak

series ordinal

2

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15 August 2017

Jong-Heun Lee

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3

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15 August 2017

Douglas O Halverson

series ordinal

4

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15 August 2017

publication date

1 August 2006

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Journal of Bioenergetics and Biomembranes

15 August 2017

published in

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15 August 2017

volume

38

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15 August 2017

issue

3-4

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15 August 2017

page(s)

151-161

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Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

15 August 2017

cites work

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https://api.crossref.org/works/10.1007/S10863-006-9039-9

Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1)

21 January 2018

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https://api.crossref.org/works/10.1007/S10863-006-9039-9

The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007/S10863-006-9039-9

Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines

21 January 2018

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https://api.crossref.org/works/10.1007/S10863-006-9039-9

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

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https://api.crossref.org/works/10.1007/S10863-006-9039-9

Phospholipase D2 directly interacts with aldolase via Its PH domain

21 January 2018

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12 December 2020

Nucleoside-diphosphate kinase-mediated signal transduction via histidyl-aspartyl phosphorelay systems in Escherichia coli.

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12 December 2020

Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23).

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12 December 2020

Quaternary structure of nucleoside diphosphate kinases

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12 December 2020

Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7

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12 December 2020

Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue

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12 December 2020

The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity

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12 December 2020

Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis

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12 December 2020

The biology of a prostate cancer metastasis suppressor protein: Raf kinase inhibitor protein

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12 December 2020

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

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12 December 2020

MKK4 and metastasis suppression: a marriage of signal transduction and metastasis research

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12 December 2020

Technical considerations for studying cancer metastasis in vivo

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12 December 2020

Association of Nucleoside Diphosphate Kinase nm23-H2 with Human Telomeres

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12 December 2020

Lbc proto-oncogene product binds to and could be negatively regulated by metastasis suppressor nm23-H2.

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12 December 2020

NDP kinase 2 interacts with two oxidative stress-activated MAPKs to regulate cellular redox state and enhances multiple stress tolerance in transgenic plants.

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12 December 2020

Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis

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12 December 2020

The protein kinase KSR interacts with 14-3-3 protein and Raf.

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12 December 2020

The GPR54 gene as a regulator of puberty

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12 December 2020

Molecular biology of breast cancer metastasis. 'Has it spread?': disarming one of the most terrifying questions

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12 December 2020

Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription

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12 December 2020

Nm23/PuF does not directly stimulate transcription through the CT element in vivo

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12 December 2020

A novel function for the nm23-H1 gene: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest

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12 December 2020

Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2/rat nucleoside diphosphate kinase alpha isoform

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12 December 2020

Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells

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12 December 2020

RhoGDI2 is an invasion and metastasis suppressor gene in human cancer

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12 December 2020

The Src-suppressed C kinase substrate, SSeCKS, is a potential metastasis inhibitor in prostate cancer

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12 December 2020

Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture

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12 December 2020

Dissemination and growth of cancer cells in metastatic sites

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12 December 2020

Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current

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12 December 2020

Interactions between Escherichia coli nucleoside-diphosphate kinase and DNA.

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12 December 2020

Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line

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12 December 2020

Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13.

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12 December 2020

Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells

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12 December 2020

The Drg-1 gene suppresses tumor metastasis in prostate cancer.

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12 December 2020

Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1

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12 December 2020

Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Specific activation of Gsalpha by an NDPK B.Gbetagamma complex in H10 cells

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12 December 2020

KSR, a novel protein kinase required for RAS signal transduction

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12 December 2020

Histidine to aspartate phosphotransferase activity of nm23 proteins: phosphorylation of aldolase C on Asp-319.

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12 December 2020

Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development

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12 December 2020

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells

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12 December 2020

The Enzymatic Activity of Drosophila AWD/NDP Kinase Is Necessary but Not Sufficient for Its Biological Function

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12 December 2020

Site-directed mutation of Nm23-H1. Mutations lacking motility suppressive capacity upon transfection are deficient in histidine-dependent protein phosphotransferase pathways in vitro.

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12 December 2020

RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis

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12 December 2020

EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells.

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12 December 2020

Effects of cytokine-mediated modulation of nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells.

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12 December 2020

Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis

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12 December 2020

Structure-based mutational and functional analysis identify human NM23-H2 as a multifunctional enzyme

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12 December 2020

Phosphorylation of geranyl and farnesyl pyrophosphates by Nm23 proteins/nucleoside diphosphate kinases

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12 December 2020

DR-nm23 gene expression in neuroblastoma cells: relationship to integrin expression, adhesion characteristics, and differentiation

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12 December 2020

Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta

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12 December 2020

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

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12 December 2020

The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54

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12 December 2020

Escherichia coli nucleoside diphosphate kinase does not act as a uracil-processing DNA repair nuclease

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12 December 2020

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

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12 December 2020

Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines

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12 December 2020

Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP

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12 December 2020

The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1.

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12 December 2020

Inhibition of cell motility after nm23 transfection of human and murine tumor cells

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12 December 2020

KSR-1 binds to G-protein betagamma subunits and inhibits beta gamma-induced mitogen-activated protein kinase activation

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12 December 2020

nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation

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12 December 2020

Evidence for a novel gene associated with low tumor metastatic potential

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12 December 2020

Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma

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12 December 2020

KiSS-1, a novel human malignant melanoma metastasis-suppressor gene

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12 December 2020

Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1

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12 December 2020

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

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12 December 2020

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

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12 December 2020

Identification of structural domains affecting transactivation potential of Nm23.

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12 December 2020

Connective tissue growth factor inhibits metastasis and acts as an independent prognostic marker in colorectal cancer.

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12 December 2020

Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis

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12 December 2020

Escherichia coli nucleoside diphosphate kinase is a uracil-processing DNA repair nuclease

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12 December 2020

Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition

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12 December 2020

Copurification of vimentin, energy metabolism enzymes, and a MER5 homolog with nucleoside diphosphate kinase. Identification of tissue-specific interactions

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12 December 2020

Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-kappaB activity

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12 December 2020

Overexpression of KAI1 suppresses in vitro invasiveness and in vivo metastasis in breast cancer cells

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12 December 2020

Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement

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12 December 2020

Mycobacterium tuberculosis and Escherichia coli nucleoside diphosphate kinases lack multifunctional activities to process uracil containing DNA

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12 December 2020

A human NDP-kinase B specifically binds single-stranded poly-pyrimidine sequences

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12 December 2020

Escherichia coli nucleoside diphosphate kinase interactions with T4 phage proteins of deoxyribonucleotide synthesis and possible regulatory functions

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12 December 2020

Metastasis suppression by breast cancer metastasis suppressor 1 involves reduction of phosphoinositide signaling in MDA-MB-435 breast carcinoma cells.

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12 December 2020

Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds.

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12 December 2020

Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway

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12 December 2020

Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma

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12 December 2020

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK

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12 December 2020

A novel function for nucleoside diphosphate kinase in Drosophila

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12 December 2020

Phosphorylation of ATP-Citrate Lyase by Nucleoside Diphosphate Kinase

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12 December 2020

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

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12 December 2020

Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1

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12 December 2020

Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer

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12 December 2020

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development

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12 December 2020

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

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12 December 2020

AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1

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12 December 2020

Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis

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12 December 2020

A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase

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12 December 2020

Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity

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12 December 2020

Analysis of the lethal interaction between the prune and Killer of prune mutations of Drosophila

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12 December 2020

Breast cancer metastatic potential correlates with a breakdown in homospecific and heterospecific gap junctional intercellular communication

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12 December 2020

Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.

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12 December 2020

Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor

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12 December 2020

Decreased expression of nucleoside diphosphate kinase alpha isoform, an nm23-H2 gene homolog, is associated with metastatic potential of rat mammary-adenocarcinoma cells

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12 December 2020

Nm23/nucleoside diphosphate kinase in human cancers

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12 December 2020

Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17

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12 December 2020

NDPK2 as a signal transducer in the phytochrome-mediated light signaling

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12 December 2020

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

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12 December 2020

Effects of all-trans retinoic acid and epidermal growth factor on the expression of nm23-H1 in human hepatocarcinoma cells

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12 December 2020

Developmental consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis.

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12 December 2020

Phytochrome signalling is mediated through nucleoside diphosphate kinase 2.

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12 December 2020

Nm23-transfected MDA-mB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A31P nuclear magnetic resonance study in vivo and in vitro

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12 December 2020

MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines

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12 December 2020

Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity

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12 December 2020

10.1007/S10863-006-9039-9

Identifiers

DOI

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15 August 2017

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