SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma (Q36548775)

14 August 2017

SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma (English)

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14 August 2017

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Takuya Fukazawa

1

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14 August 2017

Minzhe Guo

2

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14 August 2017

Naomasa Ishida

3

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14 August 2017

Tomoki Yamatsuji

4

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14 August 2017

Munenori Takaoka

5

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14 August 2017

Etsuko Yokota

6

1 reference

14 August 2017

Minoru Haisa

7

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14 August 2017

Noriko Miyake

8

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14 August 2017

Tomoko Ikeda

9

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14 August 2017

Tatsuo Okui

10

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14 August 2017

Nagio Takigawa

11

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14 August 2017

Yutaka Maeda

12

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14 August 2017

Yoshio Naomoto

13

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14 August 2017

language of work or name

English

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publication date

5 February 2016

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14 August 2017

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14 August 2017

6

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14 August 2017

1

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page(s)

20113

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Creative Commons Attribution 4.0 International

14 August 2017

start time

5 February 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease.

30 September 2017

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SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.

30 September 2017

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SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

30 September 2017

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Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma

30 September 2017

1 reference

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SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells

30 September 2017

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Pluripotent stem cell protein Sox2 confers sensitivity to LSD1 inhibition in cancer cells

30 September 2017

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Genetic alterations defining NSCLC subtypes and their therapeutic implications

30 September 2017

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The prognostic value of SOX2 expression in non-small cell lung cancer: a meta-analysis

30 September 2017

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The emerging role of SOX2 in cell proliferation and survival and its crosstalk with oncogenic signaling in lung cancer.

30 September 2017

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Targeting genomic alterations in squamous cell lung cancer

30 September 2017

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High SOX2 levels predict better outcome in non-small cell lung carcinomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma

30 September 2017

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Glucocorticoid treatment of MCMV infected newborn mice attenuates CNS inflammation and limits deficits in cerebellar development.

30 September 2017

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Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

30 September 2017

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Comprehensive genomic characterization of squamous cell lung cancers

30 September 2017

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Epithelial-mesenchymal transitions: insights from development

30 September 2017

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Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients

30 September 2017

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Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways

30 September 2017

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SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells

30 September 2017

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Squamous Cell Carcinoma of the Lung: Molecular Subtypes and Therapeutic Opportunities

30 September 2017

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Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation

30 September 2017

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The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors

30 September 2017

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Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells

30 September 2017

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Epithelial-mesenchymal transitions in development and disease

30 September 2017

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SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

30 September 2017

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Multiple roles for Sox2 in the developing and adult mouse trachea

30 September 2017

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Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer

30 September 2017

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The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

30 September 2017

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Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation

30 September 2017

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SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis

30 September 2017

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Transcriptional control of lung morphogenesis

30 September 2017

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Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

Multipotent cell lineages in early mouse development depend on SOX2 function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

WAF1, a potential mediator of p53 tumor suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

Sox2 expression in pulmonary non-small cell and neuroendocrine carcinomas

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

SOX2 oncogenes amplified and operate to activate AKT signaling in gastric cancer and predict immunotherapy responsiveness

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742851

SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/SREP20113

21 January 2018

Identifiers

DOI

10.1038/SREP20113

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26846300

1 reference