ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block (Q36503126)

14 August 2017

ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block (English)

1 reference

14 August 2017

Sheng Cao

1

1 reference

14 August 2017

Yibin Wang

series ordinal

2

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14 August 2017

Xiaohua Peng

series ordinal

3

1 reference

14 August 2017

language of work or name

English

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publication date

29 February 2012

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Chemistry—A European Journal

14 August 2017

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14 August 2017

18

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14 August 2017

13

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14 August 2017

3850-3854

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Hydrogen Peroxide Inducible DNA Cross-Linking Agents: Targeted Anticancer Prodrugs

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Photogeneration and reactivity of naphthoquinone methides as purine selective DNA alkylating agents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Hydrogen peroxide activated matrix metalloproteinase inhibitors: a prodrug approach

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Protein binding has a large effect on radical mediated DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Molecular imaging of hydrogen peroxide produced for cell signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Formation and repair of interstrand cross-links in DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Oxygen independent DNA interstrand cross-link formation by a nucleotide radical

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Boronate-based fluorescent probes for imaging cellular hydrogen peroxide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

DNA interstrand cross-link formation initiated by reaction between singlet oxygen and a modified nucleotide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Binol quinone methides as bisalkylating and DNA cross-linking agents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Increased Nox1 and hydrogen peroxide in prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

ROS stress in cancer cells and therapeutic implications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

A Transient Product of DNA Alkylation Can Be Stabilized by Binding Localization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Repair of DNA interstrand cross-links

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Alkylation of amino acids and glutathione in water by o-quinone methide. Reactivity and selectivity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Mitomycin C: small, fast and deadly (but very selective)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Persistent oxidative stress in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Production of large amounts of hydrogen peroxide by human tumor cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

A new method for sequencing DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Using hydroxyl radical to probe DNA structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535311

Dynamic cross-linking is retained in duplex DNA after multiple exchange of strands.

28 June 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

Immortalizing a transient electrophile for DNA cross-linking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

A potent, water-soluble and photoinducible DNA cross-linking agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

Covalent structure of a nitrogen mustard-induced DNA interstrand cross-link: an N7-to-N7 linkage of deoxyguanosine residues at the duplex sequence 5'-d(GNC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

A Unique Paradigm for a Turn-ON Near-Infrared Cyanine-Based Probe: Noninvasive Intravital Optical Imaging of Hydrogen Peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CHEM.201200075

Development of highly selective and sensitive probes for hydrogen

21 January 2018

1 reference

12 December 2020

Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo

1 reference

12 December 2020

Synthesis and biological studies of inducible DNA cross-linking agents

1 reference

12 December 2020

Comparison of hydrogen peroxide generation and the content of lipid peroxidation products in lung cancer tissue and pulmonary parenchyma

1 reference

12 December 2020

Identifiers

DOI

10.1002/CHEM.201200075

1 reference

14 August 2017

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14 August 2017

PubMed publication ID

22378607

1 reference