Late sodium current in failing heart: friend or foe? (Q36496273)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Late sodium current in failing heart: friend or foe? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

1

1 reference

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7 January 2020

author name string

Albertas Undrovinas

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

publication date

10 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

Progress in Biophysics and Molecular Biology

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

volume

96

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

issue

1-3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

421-451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

Subunit dependence of Na channel slow inactivation and open channel block in cerebellar neurons

7 January 2020

cites work

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Regulation of Ca2 and Na in normal and failing cardiac myocytes

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Ca2 /calmodulin-dependent protein kinase II regulates cardiac Na channels

30 September 2017

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Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.

30 September 2017

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30 September 2017

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Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

30 September 2017

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Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload

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14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5

30 September 2017

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Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current

30 September 2017

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30 September 2017

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Neuromodulation of Na channel slow inactivation via cAMP-dependent protein kinase and protein kinase C.

30 September 2017

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Molecular basis of arrhythmias

30 September 2017

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A multi-modal composition of the late Na current in human ventricular cardiomyocytes

30 September 2017

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Molecular physiology of cardiac repolarization

30 September 2017

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Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromes

30 September 2017

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Modulation of the cardiac sodium channel NaV1.5 by Fyn, a Src family tyrosine kinase.

30 September 2017

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Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.

30 September 2017

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A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction

30 September 2017

1 reference

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Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart

30 September 2017

1 reference

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What causes sudden death in heart failure?

30 September 2017

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New insights into the molecular and cellular workings of the cardiac Na /Ca2 exchanger

30 September 2017

1 reference

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Calmodulin mediates Ca2 sensitivity of sodium channels

30 September 2017

1 reference

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Post-transcriptional alterations in the expression of cardiac Na channel subunits in chronic heart failure.

30 September 2017

1 reference

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Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger

30 September 2017

1 reference

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An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability

30 September 2017

1 reference

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The Na channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain.

30 September 2017

1 reference

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A modification of the Hodgkin—Huxley equations applicable to Purkinje fibre action and pacemaker potentials

30 September 2017

2 references

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Cardiac Action and Pacemaker Potentials based on the Hodgkin-Huxley Equations

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A quantitative description of membrane current and its application to conduction and excitation in nerve

30 September 2017

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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

30 September 2017

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Adenosine production and its interaction with protection of ischemic and reperfusion injury of the myocardium

30 September 2017

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An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart

30 September 2017

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Isoform-specific modulation of voltage-gated Na( ) channels by calmodulin.

30 September 2017

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Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude

30 September 2017

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A calcium sensor in the sodium channel modulates cardiac excitability

30 September 2017

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Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues

30 September 2017

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Alterations of sodium channel kinetics and gene expression in the postinfarction remodeled myocardium

30 September 2017

1 reference

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Nomenclature of voltage-gated sodium channels

30 September 2017

1 reference

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Distribution of a persistent sodium current across the ventricular wall in guinea pigs

30 September 2017

1 reference

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Coexpression with beta(1)-subunit modifies the kinetics and fatty acid block of hH1(alpha) Na( ) channels

30 September 2017

1 reference

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Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium

30 September 2017

1 reference

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The role of the cytoskeleton in heart failure

30 September 2017

1 reference

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Intrinsic lidocaine affinity for Na channels expressed in Xenopus oocytes depends on alpha (hH1 vs. rSkM1) and beta 1 subunits

30 September 2017

1 reference

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Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes

30 September 2017

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Novel LQT-3 mutation affects Na channel activity through interactions between alpha- and beta1-subunits

30 September 2017

1 reference

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Modal behavior of the mu 1 Na channel and effects of coexpression of the beta 1-subunit

30 September 2017

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A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

30 September 2017

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Gene expression of the cardiac Na( )-Ca2 exchanger in end-stage human heart failure

30 September 2017

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Late Na channels in cardiac cells: the physiological role of background Na channels

30 September 2017

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Multimodal action of single Na channels in myocardial mouse cells

30 September 2017

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Molecular mechanism for an inherited cardiac arrhythmia

30 September 2017

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A Classification of Antiarrhythmic Actions Reassessed After a Decade of New Drugs

30 September 2017

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Patch clamp analysis of Na channel gating in mammalian myocardium: reconstruction of double pulse inactivation and voltage dependence of Na currents.

30 September 2017

1 reference

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Modal gating behavior of cardiac sodium channels in cell-free membrane patches

30 September 2017

1 reference

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Slow currents through single sodium channels of the adult rat heart

30 September 2017

1 reference

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Amphipathic lipid metabolites and their relation to arrhythmogenesis in the ischemic heart

30 September 2017

1 reference

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Events in the Cardiac Arrhythmia Suppression Trial (CAST): mortality in the entire population enrolled

30 September 2017

1 reference

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Ca(2 )-currents and intracellular [Ca2 ]i-transients in single ventricular myocytes isolated from terminally failing human myocardium

30 September 2017

1 reference

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The steady state TTX-sensitive ("window") sodium current in cardiac Purkinje fibres

30 September 2017

1 reference

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Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2 current

30 September 2017

1 reference

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Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure

30 September 2017

1 reference

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Large diameter of palytoxin-induced Na/K pump channels and modulation of palytoxin interaction by Na/K pump ligands

28 June 2018

1 reference

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[Na ]i and the driving force of the Na /Ca2 -exchanger in heart failure

28 June 2018

1 reference

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Calcium entry via Na/Ca exchange during the action potential directly contributes to contraction of failing human ventricular myocytes

28 June 2018

1 reference

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Modulation of Ca(2 ) release in cardiac myocytes by changes in repolarization rate: role of phase-1 action potential repolarization in excitation-contraction coupling

28 June 2018

1 reference

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Activation of protein kinase A modulates trafficking of the human cardiac sodium channel in Xenopus oocytes

28 June 2018

1 reference

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Cardiac Na( ) channel dysfunction in Brugada syndrome is aggravated by beta(1)-subunit

28 June 2018

1 reference

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Hypoxia increases persistent sodium current in rat ventricular myocytes

28 June 2018

1 reference

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Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure

28 June 2018

1 reference

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Reperfusion of Rat Heart After Brief Ischemia Induces Proteolysis of Calspectin (Nonerythroid Spectrin or Fodrin) by Calpain

28 June 2018

1 reference

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Cytoskeleton modulates gating of voltage-dependent sodium channel in heart

28 June 2018

1 reference

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Shortening of the action potential and reduction of pacemaker activity by lidocaine, quinidine, and procainamide in sheep cardiac purkinje fibers. An effect on Na or K currents?

28 June 2018

1 reference

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The effect of tetrodotoxin on the membrane current in cardiac muscle (Purkinje fibers)

28 June 2018

1 reference

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Late sodium current and its contribution to action potential configuration in guinea pig ventricular myocytes

28 June 2018

1 reference

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Basis for tetrodotoxin and lidocaine effects on action potentials in dog ventricular myocytes

28 June 2018

1 reference

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Slow inactivation of the sodium current in rabbit cardiac Purkinje fibres

28 June 2018

1 reference

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Modulation of cardiac sodium channel gating by lysophosphatidylcholine.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

A persistent sodium current in rat ventricular myocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Molecular basis for pharmacological differences between brain and cardiac sodium channels

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Background current in sino‐atrial node cells of the rabbit heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Two levels of resting potential in cardiac Purkinje fibers

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Effect of tetrodotoxin on action potentials of the conducting system in the dog heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

From the Hodgkin-Huxley axon to the virtual heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Ultraviolet photoalteration of late Na current in guinea-pig ventricular myocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

An increase in late sodium current potentiates the proarrhythmic activities of low-risk QT-prolonging drugs in female rabbit hearts

21 September 2018

1 reference

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Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Contribution of neuronal sodium channels to the cardiac fast sodium current INa is greater in dog heart Purkinje fibers than in ventricles

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Down-regulation of sodium current in chronic heart failure: effect of long-term therapy with carvedilol

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Late Na currents affected by alpha subunit isoform and beta1 subunit co-expression in HEK293 cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Intracellular Na( ) concentration is elevated in heart failure but Na/K pump function is unchanged

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Intracellular calcium level required for calpain activation in a single myocardial cell

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Late sodium current is a novel target for amiodarone: studies in failing human myocardium

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

beta-Adrenergic stimulation synchronizes intracellular Ca(2 ) release during excitation-contraction coupling in cardiac myocytes

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Slowly inactivating component of sodium current in ventricular myocytes is decreased by diabetes and partially inhibited by known Na( )-H( )Exchange blockers

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Abnormal cardiac Na( ) channel properties and QT heart rate adaptation in neonatal ankyrin(B) knockout mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Relationship between action potential, contraction-relaxation pattern, and intracellular Ca2 transient in cardiomyocytes of dogs with chronic heart failure

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Modelling of sodium-overload arrhythmias and their suppression

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Characteristics of lidocaine block of sodium channels in single human atrial cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Slow inactivation of a tetrodotoxin-sensitive current in canine cardiac Purkinje fibers

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Electrophysiological Actions of Lidocaine on Canine Ventricular Muscle and Purkinje Fibers

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

The sodium channel from rat brain. Role of the beta 1 and beta 2 subunits in saxitoxin binding

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Sites of action and active forms of lidocaine and some derivatives on cardiac Purkinje fibers

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267741

Gating of the late Na channel in normal and failing human myocardium

21 September 2018

1 reference

12 December 2020

Alterations in Early Action Potential Repolarization Causes Localized Failure of Sarcoplasmic Reticulum Ca 2 Release

1 reference

12 December 2020

Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation

1 reference

12 December 2020

Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesis

1 reference

12 December 2020

Rapid onset of lysophosphatidylcholine-induced modification of whole cell cardiac sodium current kinetics

1 reference

12 December 2020

Mortality following ventricular arrhythmia suppression by encainide, flecainide, and moricizine after myocardial infarction. The original design concept of the Cardiac Arrhythmia Suppression Trial (CAST)

1 reference

12 December 2020

Secondary structure of the human cardiac Na channel C terminus: evidence for a role of helical structures in modulation of channel inactivation

1 reference

12 December 2020

Ischemic poison lysophosphatidylcholine modifies heart sodium channels gating inducing long-lasting bursts of openings

1 reference

12 December 2020

Prolongation of the QTc interval is seen uniformly during early transmural ischemia

1 reference

12 December 2020

Reduced Contraction and Altered Frequency Response of Isolated Ventricular Myocytes From Patients With Heart Failure

1 reference

12 December 2020

The effects of lysophosphatidylcholine, a toxic metabolite of ischemia, on the components of cardiac excitability in sheep Purkinje fibers

1 reference

12 December 2020

Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodulin: does VDSC acquire calmodulin-mediated Ca2 -sensitivity?

1 reference

12 December 2020

Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure

1 reference

12 December 2020

The dependence of slow inward current in Purkinje fibres on the extracellular calcium-concentration

1 reference

12 December 2020

Modulation of canine myocardial sarcolemmal membrane fluidity by amphiphilic compounds

1 reference

12 December 2020

Identification of gating modes in single native Na channels from human atrium and ventricle

1 reference

12 December 2020

Lysophosphoglycerides and ventricular fibrillation early after onset of ischemia

1 reference

12 December 2020

Action potential duration, rate of stimulation, and intracellular sodium

1 reference

12 December 2020

Dyssynchronous Ca(2 ) sparks in myocytes from infarcted hearts

1 reference

12 December 2020

Background inward current in ventricular and atrial cells of the guinea-pig

1 reference

12 December 2020

10.1016/J.PBIOMOLBIO.2007.07.010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17854868 AND SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

17854868

1 reference