Influence of Panax ginseng on Cytochrome P450 (CYP)3A and P‐glycoprotein (P‐gp) Activity in Healthy Participants (Q36469701)

14 August 2017

Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants (English)

1 reference

14 August 2017

Influence of Panax ginseng on Cytochrome P450 (CYP)3A and P‐glycoprotein (P‐gp) Activity in Healthy Participants (English)

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https://api.crossref.org/works/10.1177/0091270011407194

3 December 2024

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6

Joseph A. Kovacs

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3 December 2024

author name string

Cheryl Chairez

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14 August 2017

Christine Y. Malati

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3 December 2024

Sarah M. Robertson

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3 December 2024

Jennifer D. Hunt

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3 December 2024

Raul M. Alfaro

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Scott R. Penzak

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3 December 2024

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6 June 2011

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14 August 2017

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https://europepmc.org/articles/PMC3523324

3 December 2024

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https://europepmc.org/articles/PMC3523324?pdf=render

3 December 2024

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https://doi.org/10.1177/0091270011407194

3 December 2024

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3 December 2024

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https://accp1.onlinelibrary.wiley.com/doi/pdf/10.1177/0091270011407194

3 December 2024

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The Journal of Clinical Pharmacology

3 December 2024

published in

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14 August 2017

52

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14 August 2017

6

1 reference

14 August 2017

932-939

1 reference

Echinacea purpurea significantly induces cytochrome P450 3A activity but does not alter lopinavir-ritonavir exposure in healthy subjects

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation

30 September 2017

1 reference

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Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations

30 September 2017

1 reference

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Interactions between herbal medicines and prescribed drugs: an updated systematic review

30 September 2017

1 reference

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Ginsenosides chemistry, biosynthesis, analysis, and potential health effects

30 September 2017

1 reference

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Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium

30 September 2017

1 reference

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Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans

30 September 2017

1 reference

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Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein

30 September 2017

1 reference

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Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans

30 September 2017

1 reference

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Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba

30 September 2017

1 reference

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Trends in use of complementary and alternative medicine by US adults: 1997-2002.

30 September 2017

1 reference

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The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo

30 September 2017

1 reference

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Functional characterization of monocarboxylic acid, large neutral amino acid, bile acid and peptide transporters, and P-glycoprotein in MDCK and Caco-2 cells

30 September 2017

1 reference

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Panax ginseng: a systematic review of adverse effects and drug interactions

30 September 2017

1 reference

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Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

30 September 2017

1 reference

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The effect of garlic supplements on the pharmacokinetics of saquinavir

30 September 2017

1 reference

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The effect of rifampin administration on the disposition of fexofenadine

30 September 2017

1 reference

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Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Cytochrome P-450 3A4: regulation and role in drug metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey

30 September 2017

1 reference

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The human hepatic cytochromes P450 involved in drug metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol

28 June 2018

1 reference

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Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity

28 June 2018

1 reference

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Low hepatic cytochrome P450 3A activity is a risk for corticosteroid-induced osteonecrosis

28 June 2018

1 reference

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Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics

21 September 2018

1 reference

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Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Drug interaction potential of soy extract and Panax ginseng

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523324

Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir

21 September 2018

1 reference

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Single plasma concentrations of 1'-hydroxymidazolam or the ratio of 1'-hydroxymidazolam:midazolam do not predict midazolam clearance in healthy subjects

21 September 2018

1 reference

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Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans

21 September 2018

1 reference

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In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration

21 September 2018

1 reference

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Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study

21 September 2018

1 reference

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Indinavir concentrations and St John's wort.

21 September 2018

1 reference

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Deglycosylated ginsenosides are more potent inducers of CYP1A1, CYP1A2 and CYP3A4 expression in HepG2 cells than glycosylated ginsenosides

21 September 2018

1 reference

12 December 2020

An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures

1 reference

12 December 2020

Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men

1 reference

12 December 2020

Ginsenoside metabolites, rather than naturally occurring ginsenosides, lead to inhibition of human cytochrome P450 enzymes

1 reference

12 December 2020

Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects

1 reference

12 December 2020

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14 August 2017

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14 August 2017

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