Pharmacogenetics of the human beta-adrenergic receptors (Q36459142)

14 August 2017

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title

Pharmacogenetics of the human beta-adrenergic receptors (English)

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14 August 2017

Taylor MR

1

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14 August 2017

publication date

25 April 2006

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The Pharmacogenomics Journal

14 August 2017

published in

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14 August 2017

volume

7

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14 August 2017

issue

1

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14 August 2017

page(s)

29-37

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The pharmacologic approach to the treatment of obesity

14 August 2017

cites work

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes

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beta(2)-adrenergic receptor pharmacogenetics

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Upregulation of beta(3)-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium

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Association of β3-adrenoceptor polymorphism with obesity and diabetes: current status

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Polymorphisms of the beta(2)-adrenergic receptor determine exercise capacity in patients with heart failure

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Future research directions in asthma: an NHLBI Working Group report

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7 January 2021

Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Genomic approaches to understanding asthma

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pharmacogenetics of Asthma

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Changes in myocardial and vascular receptors in heart failure

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Adrenergic nervous system in heart failure

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Association of Trp64Arg beta 3-adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta 3-adrenoreceptor gene polymorphism and leptin. Lack of relationship in type 2 diabetic patients.

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta3-adrenoceptors in the cardiovascular system

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The emerging pharmacogenomics of the beta-adrenergic receptors

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Molecular cloning of a human beta 3-adrenergic receptor cDNA.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The promoter and intron/exon structure of the human and mouse beta 3-adrenergic-receptor genes

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta-adrenergic receptor polymorphisms: cardiovascular disease associations and pharmacogenetics

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The expanding spectrum of G protein diseases

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Racial differences in the frequencies of cardiac beta(1)-adrenergic receptor polymorphisms: analysis of c145A>G and c1165G>C

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta1-adrenoceptor gene variations: a role in idiopathic dilated cardiomyopathy?

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

A novel polymorphism in the gene coding for the beta(1)-adrenergic receptor associated with survival in patients with heart failure

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Polymorphism in the beta(1)-adrenergic receptor gene and hypertension

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Characterization of a Unique Genetic Variant in the β1-adrenoceptor Gene and Evaluation of its Role in Idiopathic Dilated Cardiomyopathy

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https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

beta2 adrenoceptor gene polymorphisms in cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Polymorphisms of the beta2 -adrenoceptor (ADRB2) gene and essential hypertension: the ECTIM and PEGASE studies

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Variability in beta-adrenergic receptor response in the vasculature: Role of receptor polymorphism

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pharmacogenetics of beta-1- and beta-2-adrenergic receptors

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Polymorphisms of the 5' leader cistron of the human beta2-adrenergic receptor regulate receptor expression

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Trp64Arg Mutation of ?-Adrenergic Receptor in Essential Hypertension Insulin Resistance and the Adrenergic System

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Physiological significance of beta-adrenergic receptor polymorphisms: in-vivo or in-vitro veritas?

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Common polymorphisms of beta1-adrenoceptor: identification and rapid screening assay

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The tissue distribution of the human beta3-adrenoceptor studied using a monoclonal antibody: direct evidence of the beta3-adrenoceptor in human adipose tissue, atrium and skeletal muscle

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pancreatic beta-cells expressing the Arg64 variant of the beta(3)-adrenergic receptor exhibit abnormal insulin secretory activity.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Trp64Arg polymorphism of the beta3-adrenergic receptor gene, pre-pregnancy obesity and risk of pre-eclampsia

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

betaAR signaling required for diet-induced thermogenesis and obesity resistance

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The human beta 3-adrenoceptor: the search for a physiological function

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Regulation of beta3‐adrenoceptor expression in white fat cells*

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Insulin resistance and type 2 diabetes mellitus: its relationship with the beta 3-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Adrenoceptor genes in human obesity

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta-adrenoceptor polymorphisms

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Amino acid 49 polymorphisms of the human beta1-adrenergic receptor affect agonist-promoted trafficking

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The myocardium-protective Gly-49 variant of the beta 1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulation

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta 2 adrenergic receptor 5' haplotypes influence promoter activity

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Effects of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta1-adrenergic receptor gene polymorphisms and response to beta1-adrenergic receptor blockade in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Ser49Gly of beta1-adrenergic receptor is associated with effective beta-blocker dose in dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Time to draw breath: asthma-susceptibility genes are identified

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Polymorphisms of the beta2-adrenergic receptor gene (ADRB2) in relation to cardiovascular risk factors in men.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Positional genomic analysis identifies the beta(2)-adrenergic receptor gene as a susceptibility locus for human hypertension

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Interaction between cardiac sympathetic drive and heart rate in heart failure: modulation by adrenergic receptor genotype

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pharmacogenomics in hypertension: present practicalities and future potential

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pharmacogenomics of blood pressure response to antihypertensive treatment

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Functional responses of human beta1 adrenoceptors with defined haplotypes for the common 389R>G and 49S>G polymorphisms.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The CAREGENE study: polymorphisms of the beta1-adrenoceptor gene and aerobic power in coronary artery disease

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Human beta2-adrenergic receptor gene haplotypes and venodilation in vivo

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Differential desensitization of homozygous haplotypes of the beta2-adrenergic receptor in lymphocytes

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Association of beta2 adrenergic receptor polymorphisms and related haplotypes with triglyceride and LDL-cholesterol levels

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Haplotype analysis of the beta2 adrenergic receptor gene and risk of myocardial infarction in humans

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pharmacogenetics and response to beta-adrenergic receptor antagonists in heart failure

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Pharmacogenomics of heart failure -- focus on drug disposition and action

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

The Arg389Gly beta1-adrenoceptor gene polymorphism determines contractile response to catecholamines

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men.

1 reference

https://api.crossref.org/works/10.1038/SJ.TPJ.6500393

7 January 2021

Identifiers

DOI

10.1038/SJ.TPJ.6500393

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14 August 2017

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