Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of type 1 diabetes (Q36457697)

14 August 2017

Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of type 1 diabetes (English)

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14 August 2017

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Shraddha S Vadvalkar

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14 August 2017

C Nathan Baily

2

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14 August 2017

Satoshi Matsuzaki

3

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14 August 2017

Melinda West

4

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14 August 2017

Yasvir A Tesiram

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14 August 2017

Kenneth M Humphries

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14 August 2017

language of work or name

English

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publication date

1 January 2013

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14 August 2017

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449

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1

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253-261

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describes a project that uses

14 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3518897/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

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SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism

30 September 2017

1 reference

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4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.

30 September 2017

1 reference

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Mitochondrial dysfunction in diabetic cardiomyopathy

30 September 2017

1 reference

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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

30 September 2017

1 reference

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Mitochondria in the diabetic heart

30 September 2017

1 reference

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

30 September 2017

1 reference

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Diabetic cardiomyopathy, causes and effects

30 September 2017

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30 September 2017

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Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria

30 September 2017

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30 September 2017

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

30 September 2017

1 reference

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A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

30 September 2017

1 reference

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SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

30 September 2017

1 reference

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Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.

30 September 2017

1 reference

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Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

30 September 2017

1 reference

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Diabetic Cardiomyopathy in OVE26 Mice Shows Mitochondrial ROS Production and Divergence Between In Vivo and In Vitro Contractility

30 September 2017

1 reference

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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

30 September 2017

1 reference

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Early myocardial dysfunction in streptozotocin-induced diabetic mice: a study using in vivo magnetic resonance imaging (MRI).

30 September 2017

1 reference

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Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

30 September 2017

1 reference

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Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart

30 September 2017

1 reference

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Myocardial substrate metabolism in the normal and failing heart

30 September 2017

1 reference

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Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence

30 September 2017

1 reference

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Topology of superoxide production from different sites in the mitochondrial electron transport chain

30 September 2017

1 reference

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Biochemistry and molecular cell biology of diabetic complications

30 September 2017

1 reference

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

30 September 2017

1 reference

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Diabetes and the control of pyruvate dehydrogenase in rat heart mitochondria by concentration ratios of adenosine triphosphate/adenosine diphosphate, of reduced/oxidized nicotinamide-adenine dinucleotide and of acetyl-coenzyme A/coenzyme A

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction

30 September 2017

1 reference

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Regulation of energy substrate metabolism in the diabetic heart

28 June 2018

1 reference

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Regulation of heart muscle pyruvate dehydrogenase kinase

28 June 2018

1 reference

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Calmodulin-induced early-onset diabetes in transgenic mice

28 June 2018

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Differential labeling of the catalytic subunit of cAMP-dependent protein kinase with acetic anhydride: substrate-induced conformational changes

28 June 2018

1 reference

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Amino acid transamination is crucial for ischaemic cardioprotection in normal and preconditioned isolated rat hearts--focus on L-glutamate.

28 June 2018

1 reference

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Inhibition of succinate-linked respiration and complex II activity by hydrogen peroxide.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Overexpression of metallothionein reduces diabetic cardiomyopathy.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Triton X-100 as a specific inhibitor of the mammalian NADH-ubiquinone oxidoreductase (Complex I).

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518897

Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23030792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20121038

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23030792

1 reference