Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma (Q36456479)

14 August 2017

Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma (English)

1 reference

14 August 2017

Christophe Paget

1

0 references

Mark J. Smyth

object named as

Mark J Smyth

6

0 references

David M Thomas

object named as

David M Thomas

5

0 references

author name string

Helene Duret

2

1 reference

14 August 2017

Shin Foong Ngiow

3

1 reference

14 August 2017

Maya Kansara

4

1 reference

14 August 2017

1 November 2012

1 reference

14 August 2017

1 reference

14 August 2017

1

1 reference

14 August 2017

8

1 reference

14 August 2017

1313-1322

1 reference

Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Hedgehog pathway as a drug target: Smoothened inhibitors in development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Hedgehog inhibition with the orally bioavailable Smo antagonist LDE225 represses tumor growth and prolongs survival in a transgenic mouse model of islet cell neoplasms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Natural Innate and Adaptive Immunity to Cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Hedgehog signaling and therapeutics in pancreatic cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Smoothened as a new therapeutic target for human osteosarcoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

GDC-0449-a potent inhibitor of the hedgehog pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Inhibition of osteosarcoma cell proliferation by the Hedgehog-inhibitor cyclopamine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Sonic hedgehog signalling in T-cell development and activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Calreticulin exposure dictates the immunogenicity of cancer cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Immunosuppressive strategies that are mediated by tumor cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Blockade of B7-H1 on macrophages suppresses CD4 T cell proliferation by augmenting IFN-gamma-induced nitric oxide production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

The Hedgehog response network: sensors, switches, and routers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Role of GLI2 in the growth of human osteosarcoma

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161/ONCI.21680

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161/ONCI.21680

Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518504

Sonic Hedgehog Signaling Modulates Activation of and Cytokine Production by Human Peripheral CD4 T Cells

21 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23243595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PARAMETERS OF RADIATION DOSAGE THAT INFLUENCE PRODUCTION OF OSTEOGENIC SARCOMAS IN MICE

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23243595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/ONCI.21680

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23243595

1 reference