Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/Sp proteins (Q36447447)

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English	Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/Sp proteins	scientific article

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Europe PubMed Central

PMC publication ID

14 August 2017

Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/Sp proteins (English)

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Europe PubMed Central

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14 August 2017

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Stephen Safe

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14 August 2017

author name string

Kelly J Higgins

1

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14 August 2017

Shengxi Liu

2

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14 August 2017

Maen Abdelrahim

3

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14 August 2017

Kathryn Vanderlaag

4

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Europe PubMed Central

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14 August 2017

Xinyi Liu

5

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Weston Porter

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Richard Metz

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publication date

15 November 2007

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14 August 2017

Molecular Endocrinology

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14 August 2017

22

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Europe PubMed Central

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14 August 2017

2

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14 August 2017

388-402

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Europe PubMed Central

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14 August 2017

Novel role of the RET finger protein in estrogen receptor-mediated transcription in MCF-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234589

30 September 2017

Vascular endothelial growth factor receptor-2 expression is induced by 17beta-estradiol in ZR-75 breast cancer cells by estrogen receptor alpha/Sp proteins.

1 reference

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30 September 2017

Sp transcription factor family and its role in cancer

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30 September 2017

Vascular endothelial growth factor receptor-2: counter-regulation by the transcription factors, TFII-I and TFII-IRD1

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30 September 2017

A life-long search for the molecular pathways of steroid hormone action

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30 September 2017

AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer

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30 September 2017

Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.

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30 September 2017

17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization

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30 September 2017

Transcription factor cross-talk: the estrogen receptor and NF-kappaB.

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30 September 2017

Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity

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30 September 2017

Nuclear receptor-mediated transactivation through interaction with Sp proteins

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30 September 2017

An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1.

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30 September 2017

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

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30 September 2017

Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells

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30 September 2017

Coregulator function: a key to understanding tissue specificity of selective receptor modulators

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30 September 2017

Estrogen receptor corepressors -- a role in human breast cancer?

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30 September 2017

Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy

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30 September 2017

Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence

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30 September 2017

Vascular endothelial growth factor receptor-2: its unique signaling and specific ligand, VEGF-E.

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The biology of VEGF and its receptors

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Angiogenesis in health and disease

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30 September 2017

VEGF receptor expression and signaling in human bladder tumors

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30 September 2017

Dominant-negative nuclear receptor corepressor relieves transcriptional inhibition of retinoic acid receptor but does not alter the agonist/antagonist activities of the tamoxifen-bound estrogen receptor.

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30 September 2017

SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor

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30 September 2017

Regulation of DNA replication fork genes by 17beta-estradiol

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30 September 2017

Molecular determinants for the tissue specificity of SERMs

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30 September 2017

Biological role of estrogen and estrogen receptors

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30 September 2017

Transcription suppression of thromboxane receptor gene by peroxisome proliferator-activated receptor-gamma via an interaction with Sp1 in vascular smooth muscle cells

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30 September 2017

The multifaceted mechanisms of estradiol and estrogen receptor signaling.

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30 September 2017

Expresson of vascular endothelial growth factor, its receptors (FLT-1, KDR) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas

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30 September 2017

Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions

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30 September 2017

Structure and function of VEGF/VEGF-receptor system involved in angiogenesis

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30 September 2017

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

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30 September 2017

Combinatorial roles of the nuclear receptor corepressor in transcription and development

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30 September 2017

The role of CBP in estrogen receptor cross-talk with nuclear factor-kappaB in HepG2 cells

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30 September 2017

Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins

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30 September 2017

Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells

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30 September 2017

Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours

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30 September 2017

Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence

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30 September 2017

Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor

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30 September 2017

Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

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30 September 2017

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30 September 2017

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30 September 2017

Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor

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30 September 2017

Direct interactions between corepressors and coactivators permit the integration of nuclear receptor-mediated repression and activation

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28 June 2018

The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions

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28 June 2018

Angiogenesis and tumor metastasis

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28 June 2018

Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha-mediated transcription in part via interaction with nuclear receptor corepressor

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21 September 2018

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Tumor specific VEGF-A and VEGFR2/KDR protein are co-expressed in breast cancer

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21 September 2018

PPARalpha activators inhibit vascular endothelial growth factor receptor-2 expression by repressing Sp1-dependent DNA binding and transactivation

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21 September 2018

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21 September 2018

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21 September 2018

Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cells

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21 September 2018

Cell Context-Dependent Differences in the Induction of E2F-1 Gene Expression by 17β-Estradiol in MCF-7 and ZR-75 Cells

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Dynamic inhibition of nuclear receptor activation by corepressor binding

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21 September 2018

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21 September 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the vascular endothelial growth factor receptor-2/Flk-1 in breast carcinomas: correlation with proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer model

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid shear stress-induced transcriptional activation of the vascular endothelial growth factor receptor-2 gene requires Sp1-dependent DNA binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear protein interactions with the human KDR/flk-1 promoter in vivo. Regulation of Sp1 binding is associated with cell type-specific expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mediators of tumor angiogenesis: Enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18006642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1210/ME.2007-0319

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Europe PubMed Central

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14 August 2017

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24 November 2022

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Europe PubMed Central

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14 August 2017

PubMed publication ID

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Europe PubMed Central

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