Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells (Q36429815)

14 August 2017

1 reference

title

Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells (English)

1 reference

14 August 2017

1

Alison Taylor

1 reference

14 August 2017

5

Cezmi A Akdis

1 reference

14 August 2017

4

Mübeccel Akdis

1 reference

14 August 2017

2

Johan Verhagen

1 reference

14 August 2017

3

Kurt Blaser

1 reference

14 August 2017

publication date

1 April 2006

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14 August 2017

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14 August 2017

volume

117

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14 August 2017

issue

4

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14 August 2017

page(s)

433-442

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IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4 CD25 T lymphocytes

14 August 2017

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IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy

21 September 2018

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21 September 2018

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Foxp3 programs the development and function of CD4 CD25 regulatory T cells

21 September 2018

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21 September 2018

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21 September 2018

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Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25 as well as CD25- regulatory T cells

21 September 2018

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Phenotype, localization, and mechanism of suppression of CD4( )CD25( ) human thymocytes

21 September 2018

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The enemy within: keeping self-reactive T cells at bay in the periphery

21 September 2018

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CD4( )CD25( ) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

21 September 2018

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PD-1:PD-L inhibitory pathway affects both CD4( ) and CD8( ) T cells and is overcome by IL-2

21 September 2018

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T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma

21 September 2018

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Stimulation of CD25( )CD4( ) regulatory T cells through GITR breaks immunological self-tolerance

21 September 2018

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Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy.

21 September 2018

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Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors

21 September 2018

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Human cd25( )cd4( ) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

21 September 2018

1 reference

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IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells.

21 September 2018

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How cells read TGF-beta signals

21 September 2018

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Interleukin-10 and the interleukin-10 receptor

21 September 2018

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Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation.

21 September 2018

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 September 2018

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JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

21 September 2018

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T regulatory cells 1 inhibit a Th2-specific response in vivo

21 September 2018

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A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding

21 September 2018

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Immunologic self-tolerance maintained by CD25( )CD4( ) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 September 2018

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25( )CD4( ) regulatory cells that control intestinal inflammation

21 September 2018

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IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway

21 September 2018

1 reference

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IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization

21 September 2018

1 reference

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Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases

21 September 2018

1 reference

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

21 September 2018

1 reference

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Long-term clinical efficacy of grass-pollen immunotherapy

21 September 2018

1 reference

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IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy

21 September 2018

1 reference

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Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus

21 September 2018

1 reference

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Molecular basis of T cell inactivation by CTLA-4

21 September 2018

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21 September 2018

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Role of interleukin 10 in specific immunotherapy

21 September 2018

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Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom

21 September 2018

1 reference

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Regulation of immune responses by TGF-beta

21 September 2018

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A CD4 T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 September 2018

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Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.

21 September 2018

1 reference

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A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

21 September 2018

1 reference

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21 September 2018

1 reference

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PI 3-kinase: a pivotal pathway in T-cell activation?

21 September 2018

1 reference

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21 September 2018

1 reference

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Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro

21 September 2018

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21 September 2018

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21 September 2018

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Interleukin (IL)-10 inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells

21 September 2018

1 reference

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Transforming growth factor-beta 1 is the predominant paracrine inhibitor of macrophage cytokine synthesis produced by glomerular mesangial cells .

21 September 2018

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21 September 2018

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21 September 2018

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T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

21 September 2018

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Induction of hapten-specific tolerance by interleukin 10 in vivo

21 September 2018

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High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

21 September 2018

1 reference

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

21 September 2018

1 reference

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IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes

21 September 2018

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Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance

21 September 2018

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 September 2018

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B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10.

21 September 2018

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21 September 2018

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Cell interactions in the induction of tolerance: the role of thymic lymphocytes

21 September 2018

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Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production

21 September 2018

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21 September 2018

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21 September 2018

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Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

21 September 2018

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Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10.

21 September 2018

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 September 2018

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

21 September 2018

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Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice

21 September 2018

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Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4 CD25 T Cells

21 October 2018

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Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

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TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4 T cells at priming and at recall: differential involvement of Stat4 and T-bet

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IL-10 deficiency prevents IL-5 overproduction and eosinophilic inflammation in a murine model of asthma-like reaction

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IL-10 and viral IL-10 prevent IL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes

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Transforming growth factor-beta secreted from CD4( ) T cells ameliorates antigen-induced eosinophilic inflammation. A novel high-dose tolerance in the trachea

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DOI

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14 August 2017

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