Targeting the insulin-like growth factor axis as a cancer therapy. (Q36429684)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16556077 AND SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Targeting the insulin-like growth factor axis as a cancer therapy (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16556077 AND SRC:MED&resulttype=core&format=json

18 January 2020

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16556077 AND SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Tufia Haddad

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16556077 AND SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

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publication date

1 February 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16556077 AND SRC:MED&resulttype=core&format=json

18 January 2020

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18 January 2020

volume

2

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18 January 2020

issue

1

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18 January 2020

page(s)

101-110

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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

18 January 2020

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

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Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

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Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A

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Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

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The role of the IGF-I receptor in the regulation of matrix metalloproteinases, tumor invasion and metastasis

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21 January 2018

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

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Adjuvant chemotherapy plus tamoxifen compared with tamoxifen alone for postmenopausal breast cancer: meta-analysis of quality-adjusted survival.

21 January 2018

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Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

21 January 2018

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

21 January 2018

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Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

21 January 2018

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Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

21 January 2018

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Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer

21 January 2018

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Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

21 January 2018

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polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice

21 January 2018

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Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence

21 January 2018

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Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors

21 January 2018

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21 January 2018

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Antitumor activity of the growth hormone receptor antagonist pegvisomant against human meningiomas in nude mice

21 January 2018

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Interference of the IGF system as a strategy to inhibit breast cancer growth

21 January 2018

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Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

21 January 2018

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A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

21 January 2018

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Inhibition of the type I insulin-like growth factor receptor expression and signaling: novel strategies for antimetastatic therapy

21 January 2018

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

21 January 2018

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Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors

21 January 2018

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Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

21 January 2018

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21 January 2018

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A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells.

21 January 2018

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Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/14796694.2.1.101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16556077 AND SRC:MED&resulttype=core&format=json

release_k6frrjrlbzhxjjfonglispvtja

18 January 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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