siRNA screen identifies QPCT as a druggable target for Huntington's disease (Q36416732)

14 August 2017

siRNA screen identifies QPCT as a druggable target for Huntington's disease (English)

1 reference

identical protein binding

14 August 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Maria Jimenez-Sanchez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Angeleen Fleming

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Catherine Xu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Venkata P Satagopam

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

13

Freddy Heitz

1 reference

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8 June 2020

28

Andrea Caricasole

1 reference

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8 June 2020

author name string

Wun Lam

2

1 reference

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8 June 2020

Michael Hannus

3

1 reference

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8 June 2020

Birte Sönnichsen

4

1 reference

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8 June 2020

Sara Imarisio

5

1 reference

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8 June 2020

Alessia Tarditi

7

1 reference

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8 June 2020

Fiona Menzies

8

1 reference

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8 June 2020

Teresa Ed Dami

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Eduardo Gonzalez-Couto

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Giulia Lazzeroni

12

1 reference

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8 June 2020

Daniela Diamanti

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Luisa Massai

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Guido Marconi

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Chiara Caramelli

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Arianna Nencini

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Matteo Andreini

20

1 reference

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8 June 2020

Gian Luca Sardone

21

1 reference

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8 June 2020

Nicola P Caradonna

22

1 reference

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8 June 2020

Valentina Porcari

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Carla Scali

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Reinhard Schneider

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Giuseppe Pollio

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

Cahir J O'Kane

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

David C Rubinsztein

29

1 reference

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8 June 2020

publication date

6 April 2015

1 reference

14 August 2017

Nature Chemical Biology

1 reference

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8 June 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

347-354

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

describes a project that uses

8 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4696152/fullTextXML

inferred from PubMed Central ID database lookup

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30 September 2017

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30 September 2017

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28 June 2018

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Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

28 June 2018

1 reference

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Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

28 June 2018

1 reference

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Pseudopupil phenomena in the compound eye of drosophila

28 June 2018

1 reference

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The cytosolic chaperone α-crystallin B rescues folding and compartmentalization of misfolded multispan transmembrane proteins

28 June 2018

1 reference

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Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice

21 September 2018

1 reference

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Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology

21 September 2018

1 reference

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 September 2018

1 reference

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Ensemble docking into flexible active sites. Critical evaluation of FlexE against JNK-3 and beta-secretase.

21 September 2018

1 reference

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Effect of molecular charge on intestinal epithelial drug transport: pH-dependent transport of cationic drugs.

21 September 2018

1 reference

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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696152

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 September 2018

1 reference

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Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

21 September 2018

1 reference

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Expression and structural analysis of 14-3-3 proteins.

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/NCHEMBIO.1790

Involvement of polyglutamine endolysis followed by pyroglutamate formation in the pathogenesis of triplet repeat/polyglutamine-expansion diseases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25848931

12 December 2020

inferred from PubMed ID database lookup

Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25848931

12 December 2020

inferred from PubMed ID database lookup

Regulation of ERGIC-53 gene transcription in response to endoplasmic reticulum stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25848931

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1790

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

25848931

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25848931 AND SRC:MED&resulttype=core&format=json