Pre-erythrocytic malaria vaccines: towards greater efficacy (Q36403400)

14 August 2017

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title

Pre-erythrocytic malaria vaccines: towards greater efficacy (English)

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14 August 2017

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1

Adrian V S Hill

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14 August 2017

publication date

1 January 2006

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Nature Reviews Immunology

14 August 2017

published in

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14 August 2017

volume

6

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14 August 2017

issue

1

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14 August 2017

page(s)

21-32

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The global distribution of clinical episodes of Plasmodium falciparum malaria

14 August 2017

cites work

1 reference

Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara

21 January 2018

1 reference

Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial

21 January 2018

1 reference

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

21 January 2018

1 reference

Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans

21 January 2018

1 reference

Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4 and CD8 T cells producing IFN-gamma

21 January 2018

1 reference

Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers

21 January 2018

1 reference

A CD4( ) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease

21 January 2018

1 reference

Progress and challenges for malaria vaccines

21 January 2018

1 reference

Prime-boost strategies for malaria vaccine development

21 January 2018

1 reference

Malaria vaccine developments

21 January 2018

1 reference

The immunological challenge to developing a vaccine to the blood stages of malaria parasites.

21 January 2018

1 reference

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

21 January 2018

1 reference

Innate immunity to malaria

21 January 2018

1 reference

A theoretical framework for the immunoepidemiology of Plasmodium falciparum malaria.

21 January 2018

1 reference

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

21 January 2018

1 reference

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.

21 January 2018

1 reference

Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children.

21 January 2018

1 reference

The biological basis of malarial disease

21 January 2018

1 reference

Genome sequence of the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

A proteomic view of the Plasmodium falciparum life cycle

21 January 2018

1 reference

A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses

21 January 2018

1 reference

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

21 January 2018

1 reference

Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

21 January 2018

1 reference

Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

21 January 2018

1 reference

Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite protein

21 January 2018

1 reference

A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group

21 January 2018

1 reference

Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites

21 January 2018

1 reference

Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine

21 January 2018

1 reference

Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria

21 January 2018

1 reference

Malaria vaccines in development

21 January 2018

1 reference

Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

21 January 2018

1 reference

Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine.

21 January 2018

1 reference

Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine

21 January 2018

1 reference

A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts

21 January 2018

1 reference

Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720.

21 January 2018

1 reference

Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs

21 January 2018

1 reference

Immunostimulating reconstituted influenza virosomes

21 January 2018

1 reference

Exploiting conformationally constrained peptidomimetics and an efficient human-compatible delivery system in synthetic vaccine design

21 January 2018

1 reference

Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1

21 January 2018

1 reference

Gamma interferon, CD8 T cells and antibodies required for immunity to malaria sporozoites

21 January 2018

1 reference

The complexity of protective immunity against liver-stage malaria

21 January 2018

1 reference

Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

21 January 2018

1 reference

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

21 January 2018

1 reference

Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization

21 January 2018

1 reference

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein

21 January 2018

1 reference

Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8 T-cell-mediated protective immunity against malaria

21 January 2018

1 reference

Enhanced immunogenicity for CD8 T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara

21 January 2018

1 reference

Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine

21 January 2018

1 reference

Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes

21 January 2018

1 reference

Enhanced CD8 T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus

21 January 2018

1 reference

Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques

21 January 2018

1 reference

Protection of rhesus macaques against lethal Plasmodium knowlesi malaria by a heterologous DNA priming and poxvirus boosting immunization regimen

21 January 2018

1 reference

Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria.

21 January 2018

1 reference

A protein particle vaccine containing multiple malaria epitopes

21 January 2018

1 reference

Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

21 January 2018

1 reference

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

21 January 2018

1 reference

Safety of DNA and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers

21 January 2018

1 reference

Safety and immunogenicity of DNA/modified vaccinia virus ankara malaria vaccination in African adults

21 January 2018

1 reference

Phase 1 evaluation of 3 highly immunogenic prime-boost regimens, including a 12-month reboosting vaccination, for malaria vaccination in Gambian men.

21 January 2018

1 reference

A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults

21 January 2018

1 reference

Comparison of the genome sequence of FP9, an attenuated, tissue culture-adapted European strain of Fowlpox virus, with those of virulent American and European viruses

21 January 2018

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Calculation of liver-to-blood inocula, parasite growth rates, and preerythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites

21 January 2018

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Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria

21 January 2018

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Boosting of DNA vaccine-elicited gamma interferon responses in humans by exposure to malaria parasites

21 January 2018

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Induction in humans of CD8 and CD4 T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein

21 January 2018

1 reference

Human immunodeficiency virus type 1-specific immune responses in primates upon sequential immunization with adenoviral vaccine carriers of human and simian serotypes

21 January 2018

1 reference

Replication-defective vector based on a chimpanzee adenovirus

21 January 2018

1 reference

Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development

21 January 2018

1 reference

Synthetic peptide vaccine confers protection against murine malaria

21 January 2018

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Genetic control of the immune response in mice to a Plasmodium falciparum sporozoite vaccine. Widespread nonresponsiveness to single malaria T epitope in highly repetitive vaccine

21 January 2018

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Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites

21 January 2018

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Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8 T cells

21 January 2018

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Antibodies to the Plasmodium falciparum antigens circumsporozoite protein, thrombospondin-related adhesive protein, and liver-stage antigen 1 vary by ages of subjects and by season in a highland area of Kenya

21 January 2018

1 reference

A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

21 January 2018

1 reference

Central memory and effector memory T cell subsets: function, generation, and maintenance

21 January 2018

1 reference

Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays.

21 January 2018

1 reference

Evolution of epitope-specific memory CD4( ) T cells after clearance of hepatitis C virus.

21 January 2018

1 reference

Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children

21 January 2018

1 reference

Gamma interferon responses to Plasmodium falciparum liver-stage antigen 1 and thrombospondin-related adhesive protein and their relationship to age, transmission intensity, and protection against malaria

21 January 2018

1 reference

Natural regulatory T cells in infectious disease

21 January 2018

1 reference

Escape of malaria parasites from host immunity requires CD4 CD25 regulatory T cells

21 January 2018

1 reference

Differential Induction of TGF-β Regulates Proinflammatory Cytokine Production and Determines the Outcome of Lethal and NonlethalPlasmodium yoeliiInfections

21 January 2018

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Upregulation of TGF-beta, FOXP3, and CD4 CD25 regulatory T cells correlates with more rapid parasite growth in human malaria infection

21 January 2018

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Regulatory T cells suppress CD8 T cell responses induced by direct priming and cross-priming and moderate immunodominance disparities.

21 January 2018

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Opsonization by antigen-specific antibodies as a mechanism of protective immunity induced by Plasmodium falciparum circumsporozoite protein-based vaccine

21 January 2018

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Cellular immunity induced by the recombinant Plasmodium falciparum malaria vaccine, RTS,S/AS02, in semi-immune adults in The Gambia

21 January 2018

1 reference

Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein

21 January 2018

1 reference

Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum

21 January 2018

1 reference

The effect of insecticide-treated bed nets on mortality of Gambian children

21 January 2018

1 reference

A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 6. The impact of the interventions on mortality and morbidity from malaria

21 January 2018

1 reference

Common west African HLA antigens are associated with protection from severe malaria

21 January 2018

1 reference

Dynamic interactions in malaria: host heterogeneity meets parasite polymorphism.

21 January 2018

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Induction of CD4( ) T cell-dependent CD8( ) type 1 responses in humans by a malaria DNA vaccine.

21 January 2018

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Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine

21 January 2018

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Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in non-immune volunteers

21 January 2018

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A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea

21 January 2018

1 reference

Update on the clinical development of candidate malaria vaccines.

21 January 2018

1 reference

Association of interferon-gamma responses to pre-erythrocytic stage vaccine candidate antigens of Plasmodium falciparum in young Kenyan children with improved hemoglobin levels: XV. Asembo Bay Cohort Project.

31 March 2020

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Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

31 March 2020

1 reference

Immunization of man against sporozite-induced falciparum malaria

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Attenuated vaccinia virus-circumsporozoite protein recombinants confer protection against rodent malaria.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1746

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14 August 2017

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