Drug Insight: oral phosphodiesterase type 5 inhibitors for erectile dysfunction (Q36395193)

13 August 2017

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title

Drug Insight: oral phosphodiesterase type 5 inhibitors for erectile dysfunction (English)

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13 August 2017

7

Francesco Montorsi

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13 August 2017

1

Alberto Briganti

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13 August 2017

2

Andrea Salonia

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13 August 2017

6

Patrizio Rigatti

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13 August 2017

4

Antonino Saccà

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13 August 2017

5

Piero Montorsi

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13 August 2017

Andrea Gallina

3

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13 August 2017

language of work or name

English

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publication date

1 May 2005

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13 August 2017

published in

Nature Reviews Urology

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13 August 2017

volume

2

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13 August 2017

issue

5

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13 August 2017

page(s)

239-247

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Involvement of nitric oxide in the non-adrenergic non-cholinergic neurotransmission of horse deep penile arteries: role of charybdotoxin-sensitive K( )-channels.

13 August 2017

cites work

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Expression of three isoforms of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in human penile cavernosum

21 January 2018

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A population pharmacokinetic analysis of sildenafil citrate in patients with erectile dysfunction

21 January 2018

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The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil

21 January 2018

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Vardenafil increases penile rigidity and tumescence in men with erectile dysfunction after a single oral dose

21 January 2018

1 reference

Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo

21 January 2018

1 reference

A dose-escalation study to assess the efficacy and safety of sildenafil citrate in men with erectile dysfunction

21 January 2018

1 reference

The efficacy of sildenafil citrate (Viagra) in clinical populations: an update

21 January 2018

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Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial reports

21 January 2018

1 reference

Sildenafil for male erectile dysfunction: a systematic review and meta-analysis

21 January 2018

1 reference

Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. Sildenafil Diabetes Study Group.

21 January 2018

1 reference

Sildenafil citrate for the treatment of erectile dysfunction in men with Type II diabetes mellitus

21 January 2018

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Role of Viagra after radical prostatectomy.

21 January 2018

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Prognostic factors for response to sildenafil in patients with erectile dysfunction

21 January 2018

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The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: the first at-home clinical trial

21 January 2018

1 reference

Efficacy of vardenafil in men with erectile dysfunction: a flexible-dose community practice study

21 January 2018

1 reference

Safety and Efficacy of Vardenafil for the Treatment of Men With Erectile Dysfunction After Radical Retropubic Prostatectomy

21 January 2018

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Sustained efficacy and tolerability of vardenafil, a highly potent selective phosphodiesterase type 5 inhibitor, in men with erectile dysfunction: results of a randomized, double-blind, 26-week placebo-controlled pivotal trial

21 January 2018

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The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease.

21 January 2018

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On-demand IC351 (Cialis) enhances erectile function in patients with erectile dysfunction

21 January 2018

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Efficacy, safety, and treatment satisfaction of tadalafil versus placebo in patients with erectile dysfunction evaluated at tertiary-care academic centers

21 January 2018

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Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses

21 January 2018

1 reference

The International Index of Erectile Function (IIEF): a state-of-the-science review

21 January 2018

1 reference

Tadalafil in the treatment of erectile dysfunction following bilateral nerve sparing radical retropubic prostatectomy: a randomized, double-blind, placebo controlled trial

21 January 2018

1 reference

IC351 (tadalafil, Cialis): update on clinical experience

21 January 2018

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Tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones.

21 January 2018

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Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients: a RigiScan and pharmacokinetic study

21 January 2018

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Molecular mechanisms for the regulation of penile smooth muscle contractility

21 January 2018

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7 January 2021

Oxygen tension regulates the nitric oxide pathway. Physiological role in penile erection

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7 January 2021

Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle.

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7 January 2021

A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle

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7 January 2021

Effects of the nitric oxide synthase inhibitor NG-nitro-L-arginine on the erectile response to cavernous nerve stimulation in the rabbit

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7 January 2021

Gene expression of the phosphodiesterases 3A and 5A in human corpus cavernosum penis

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7 January 2021

Phosphodiesterase isoenzymes as pharmacological targets in the treatment of male erectile dysfunction.

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7 January 2021

Pharmacology of erectile function and dysfunction

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7 January 2021

Efficacy and safety of fixed-dose oral sildenafil in the treatment of erectile dysfunction of various etiologies

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7 January 2021

Sildenafil: clinical toxicology profile

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7 January 2021

Effect of high-fat breakfast and moderate-fat evening meal on the pharmacokinetics of vardenafil, an oral phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction

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7 January 2021

Sildenafil treatment of serotonin reuptake inhibitor-induced sexual dysfunction

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7 January 2021

Sildenafil for iatrogenic serotonergic antidepressant medication-induced sexual dysfunction in 4 patients

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7 January 2021

Sildenafil citrate for SSRI-induced sexual side effects

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7 January 2021

Sildenafil citrate for treatment of erectile dysfunction in men with type 1 diabetes: results of a randomized controlled trial

1 reference

7 January 2021

Treatment of erectile dysfunction after radical prostatectomy with sildenafil citrate (Viagra)

1 reference

7 January 2021

Sildenafil citrate (Viagra) after radical retropubic prostatectomy: pro

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7 January 2021

Sildenafil citrate (Viagra) after radical retropubic prostatectomy: con

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7 January 2021

Cardiovascular effects of sildenafil during exercise in men with known or probable coronary artery disease: a randomized crossover trial

1 reference

7 January 2021

Overall cardiovascular profile of sildenafil citrate

1 reference

7 January 2021

Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study

1 reference

7 January 2021

Effects of tadalafil on erectile dysfunction in men with diabetes

1 reference

7 January 2021

Cardiovascular effects of tadalafil in patients on common antihypertensive therapies

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7 January 2021

Time course of the interaction between tadalafil and nitrates

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7 January 2021

Vardenafil: a review of its use in erectile dysfunction

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7 January 2021

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

7 January 2021

Identifiers

DOI

10.1038/NCPURO0186

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13 August 2017

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