STAT3 in immune responses and inflammatory bowel diseases (Q36395001)

13 August 2017

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title

STAT3 in immune responses and inflammatory bowel diseases (English)

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inflammatory bowel diseases

13 August 2017

main subject

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inflammation

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author name string

Xin Yuan Fu

series ordinal

1

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13 August 2017

language of work or name

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1 February 2006

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13 August 2017

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13 August 2017

volume

16

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13 August 2017

issue

2

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13 August 2017

page(s)

214-219

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Growth factor signaling by receptor tyrosine kinases

13 August 2017

cites work

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Rapid activation by interferon alpha of a latent DNA-binding protein present in the cytoplasm of untreated cells

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The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction

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A protein tyrosine kinase in the interferon alpha/beta signaling pathway

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The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

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Jaks and Stats in signaling by the cytokine receptor superfamily

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A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s)

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Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

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Tyrosine phosphorylation of DNA binding proteins by multiple cytokines

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STATs and Gene Regulation

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Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

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Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

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Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

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Activation of the STAT Signaling Pathway Can Cause Expression of Caspase 1 and Apoptosis

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From PTK-STAT signaling to caspase expression and apoptosis induction

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Stats: transcriptional control and biological impact

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Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

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Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease

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Innate Immunity: The Virtues of a Nonclonal System of Recognition

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The immunology of mucosal models of inflammation

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Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

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Etiology of the inflammatory bowel diseases

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NOD proteins: an intracellular pathogen-recognition system or signal transduction modifiers?

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Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2

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Autoimmunity and apoptosis: the Crohn's connection

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Genes, microbes, and T cells--new therapeutic targets in Crohn's disease

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Immunotherapy of Crohn's disease

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Prospects for research in inflammatory bowel disease

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Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease

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Effector Th-1 cells with cytotoxic function in the intestinal lamina propria of patients with Crohn's disease

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7 January 2021

Regulatory T cells and intestinal homeostasis

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CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

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IL-6-regulated transcription factors

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7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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7 January 2021

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

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7 January 2021

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7 January 2021

Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action.

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STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

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7 January 2021

Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota

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7 January 2021

Interleukin-10-deficient mice develop chronic enterocolitis

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7 January 2021

Interleukin-10 and the interleukin-10 receptor

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7 January 2021

A CD4 T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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7 January 2021

Naturally arising Foxp3-expressing CD25 CD4 regulatory T cells in immunological tolerance to self and non-self

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7 January 2021

Cutting edge: cure of colitis by CD4 CD25 regulatory T cells

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7 January 2021

Dendritic cells and the control of immunity

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7 January 2021

Tolerogenic dendritic cells

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7 January 2021

The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria

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https://api.crossref.org/works/10.1038/SJ.CR.7310029

7 January 2021

Dendritic cell lineage, plasticity and cross-regulation

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7 January 2021

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

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7 January 2021

Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs

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7 January 2021

The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor

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7 January 2021

The nature of the principal type 1 interferon-producing cells in human blood

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7 January 2021

CD11c( )B220( )Gr-1( ) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells

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7 January 2021

Production of type I interferons: plasmacytoid dendritic cells and beyond

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7 January 2021

Reciprocal control of T helper cell and dendritic cell differentiation

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https://api.crossref.org/works/10.1038/SJ.CR.7310029

7 January 2021

Distinct dendritic cell subsets differentially regulate the class of immune response in vivo

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https://api.crossref.org/works/10.1038/SJ.CR.7310029

7 January 2021

STAT3 is required for Flt3L-dependent dendritic cell differentiation

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https://api.crossref.org/works/10.1038/SJ.CR.7310029

7 January 2021

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

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7 January 2021

Identifiers

DOI

10.1038/SJ.CR.7310029

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13 August 2017

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