Development and validation of a PCR-based assay for the selection of patients more likely to benefit from therapeutic treatment with alkylating drugs. (Q36390267)

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English	Development and validation of a PCR-based assay for the selection of patients more likely to benefit from therapeutic treatment with alkylating drugs.	scientific article

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26 January 2020

Development and validation of a PCR-based assay for the selection of patients more likely to benefit from therapeutic treatment with alkylating drugs (English)

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26 January 2020

Soterios A Kyrtopoulos

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26 January 2020

Athanasios Dimopoulos

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26 January 2020

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Dimitra T Stefanou

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26 January 2020

Hara Episkopou

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26 January 2020

Aristotelis Bamias

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26 January 2020

Maria Gkotzamanidou

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26 January 2020

Christina Bamia

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26 January 2020

Christina Liakou

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26 January 2020

Margarita Bekyrou

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26 January 2020

Petros P Sfikakis

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26 January 2020

Vassilis L Souliotis

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26 January 2020

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1 November 2012

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26 January 2020

British Journal of Clinical Pharmacology

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26 January 2020

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26 January 2020

5

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26 January 2020

842-853

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26 January 2020

The repair of melphalan-induced DNA adducts in the transcribed strand of active genes is subject to a strong polarity effect

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30 September 2017

A fluorescence microplate cytotoxicity assay with a 4-log dynamic range that identifies synergistic drug combinations

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30 September 2017

Cellular processing of platinum anticancer drugs

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30 September 2017

High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma

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30 September 2017

Particular aspects of platinum compounds used at present in cancer treatment

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30 September 2017

Measuring gene-specific nucleotide excision repair in human cells using quantitative amplification of long targets from nanogram quantities of DNA.

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30 September 2017

Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant

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30 September 2017

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

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30 September 2017

DNA repair: enzymatic mechanisms and relevance to drug response

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30 September 2017

Strand-specific measurement of cisplatin-induced DNA damage and repair using quantitative PCR.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

30 September 2017

DNA damage by anticancer agents and its repair: mapping in cells at the subgene level with quantitative polymerase chain reaction.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

30 September 2017

Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

30 September 2017

General method for quantifying base adducts in specific mammalian genes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

30 September 2017

A polymerase chain reaction-based method to detect cisplatin adducts in specific genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

30 September 2017

Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay

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30 September 2017

Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

28 June 2018

Platinum-DNA damage in leukocyte DNA of patients receiving carboplatin and cisplatin chemotherapy, measured by atomic absorption spectrometry

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495149

28 June 2018

Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321.

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21 January 2018

Quantitative determination of melphalan DNA adducts using HPLC - inductively coupled mass spectrometry

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https://api.crossref.org/works/10.1111/J.1365-2125.2012.04274.X

21 January 2018

Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards

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https://api.crossref.org/works/10.1111/J.1365-2125.2012.04274.X

21 January 2018

Damage formation and repair efficiency in the p53 gene of cell lines and blood lymphocytes assayed by multiplex long quantitative polymerase chain reaction

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https://api.crossref.org/works/10.1111/J.1365-2125.2012.04274.X

21 January 2018

Time response of carboplatin-induced nephrotoxicity in rats

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https://api.crossref.org/works/10.1111/J.1365-2125.2012.04274.X

21 January 2018

Extent of Damage and Repair in thep53Tumor-Suppressor Gene After Treatment of Myeloma Patients With High-Dose Melphalan and Autologous Blood Stem-Cell Transplantation Is Individualized and May Predict Clinical Outcome

1 reference

https://api.crossref.org/works/10.1111/J.1365-2125.2012.04274.X

21 January 2018

Melphalan-induced DNA damage in vitro as a predictor for clinical outcome in multiple myeloma

1 reference

https://api.crossref.org/works/10.1111/J.1365-2125.2012.04274.X

21 January 2018

Gene-specific formation and repair of DNA monoadducts and interstrand cross-links after therapeutic exposure to nitrogen mustards

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

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Renal clearance and protein binding of melphalan in patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

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Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

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Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

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inferred from PubMed ID database lookup

Gene-specific damage produced by cisplatin, ormaplatin and UV light in human cells as assayed by the polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

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Regulation of bcl-2 and fas expression in primary activation of human peripheral lymphocytes is not sensitive to dexamethasone or cyclosporin-A

1 reference

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12 December 2020

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A monofunctional derivative of melphalan: preparation, DNA alkylation products, and determination of the specificity of monoclonal antibodies that recognize melphalan-DNA adducts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

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inferred from PubMed ID database lookup

Relationship between platinum-DNA adducts in leukocytes of patients with advanced germ cell cancer and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage by nitrogen mustard in a gene containing multiple Sp1-binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PCR-based methods for detecting DNA damage and its repair at the sub-gene and single nucleotide levels in cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22432918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2012.04274.X

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Europe PubMed Central

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26 January 2020

PMC publication ID

1 reference

Europe PubMed Central

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26 January 2020

PubMed publication ID

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Europe PubMed Central

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26 January 2020

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