Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation (Q36384570)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

review article

1 reference

title

Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

main subject

endoplasmic reticulum

0 references

author

Yien Che Tsai

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Zlatka Kostova

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

Allan M Weissman

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

publication date

8 September 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

Seminars in Cell & Developmental Biology

9 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

volume

18

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

issue

6

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9 January 2020

page(s)

770-779

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

9 January 2020

cites work

1 reference

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The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

30 September 2017

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A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

30 September 2017

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Structural insights into the p97-Ufd1-Npl4 complex.

30 September 2017

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Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'

30 September 2017

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Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation

30 September 2017

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A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

30 September 2017

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Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase

30 September 2017

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Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78

30 September 2017

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RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene

30 September 2017

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Ubiquitin ligase gp78 increases solubility and facilitates degradation of the Z variant of alpha-1-antitrypsin

30 September 2017

1 reference

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Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation

30 September 2017

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Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

30 September 2017

1 reference

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Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

30 September 2017

1 reference

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A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

30 September 2017

1 reference

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An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery

30 September 2017

1 reference

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Resistance to endoplasmic reticulum stress is an acquired cellular characteristic of rheumatoid synovial cells

30 September 2017

1 reference

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A novel route for F-box protein-mediated ubiquitination links CHIP to glycoprotein quality control

30 September 2017

1 reference

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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Ubx2 links the Cdc48 complex to ER-associated protein degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Yos9 protein is essential for degradation of misfolded glycoproteins and may function as lectin in ERAD.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Yos9p detects and targets misfolded glycoproteins for ER-associated degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen

30 September 2017

1 reference

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The biochemistry of Parkinson's disease

30 September 2017

1 reference

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Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates

30 September 2017

1 reference

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TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

30 September 2017

1 reference

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Essential role of synoviolin in embryogenesis

30 September 2017

1 reference

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A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins

30 September 2017

1 reference

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Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells.

30 September 2017

1 reference

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AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

30 September 2017

1 reference

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

A membrane protein required for dislocation of misfolded proteins from the ER

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

30 September 2017

1 reference

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N-terminal ubiquitination: more protein substrates join in.

30 September 2017

1 reference

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Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

30 September 2017

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Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

30 September 2017

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Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains

30 September 2017

1 reference

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Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family

30 September 2017

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Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

30 September 2017

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Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding

30 September 2017

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Mechanism of ubiquitin recognition by the CUE domain of Vps9p

30 September 2017

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Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

30 September 2017

1 reference

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A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1

30 September 2017

1 reference

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CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

30 September 2017

1 reference

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A role for mammalian Ubc6 homologues in ER-associated protein degradation.

30 September 2017

1 reference

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The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway

30 September 2017

1 reference

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

30 September 2017

1 reference

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

30 September 2017

1 reference

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

30 September 2017

1 reference

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

30 September 2017

1 reference

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The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

30 September 2017

1 reference

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A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

30 September 2017

1 reference

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

30 September 2017

1 reference

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Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p

30 September 2017

1 reference

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Mechanisms underlying ubiquitination

30 September 2017

1 reference

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Themes and variations on ubiquitylation

30 September 2017

1 reference

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Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Degradation signals recognized by the Ubc6p-Ubc7p ubiquitin-conjugating enzyme pair

30 September 2017

1 reference

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A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

30 September 2017

1 reference

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The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein

30 September 2017

1 reference

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A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Role of Cue1p in ubiquitination and degradation at the ER surface

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Improved prognosis assessment for patients with bladder carcinoma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Expression of autocrine motility factor (AMF) and its receptor, AMFR, in human breast cancer

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Overexpression of autocrine motility factor receptor (AMFR) in NIH3T3 fibroblasts induces cell transformation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Expression of autocrine motility factor receptor in colorectal cancer as a predictor for disease recurrence

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200800

Genetic interactions of Hrd3p and Der3p/Hrd1p with Sec61p suggest a retro-translocation complex mediating protein transport for ER degradation

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17950636

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A RING-H2 finger motif is essential for the function of Der3/Hrd1 in endoplasmic reticulum associated protein degradation in the yeast Saccharomyces cerevisiae

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17950636

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.SEMCDB.2007.09.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17950636 AND SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

17950636

1 reference