The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction (Q36377236)

13 August 2017

The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction (English)

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13 August 2017

J Wu

1

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13 August 2017

Q Zhao

series ordinal

2

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13 August 2017

T Kurosaki

series ordinal

3

1 reference

13 August 2017

A Weiss

series ordinal

4

1 reference

13 August 2017

language of work or name

English

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publication date

1 May 1997

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Journal of Experimental Medicine

13 August 2017

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13 August 2017

185

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13 August 2017

10

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13 August 2017

1877-1882

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Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Lck regulates Vav activation of members of the Rho family of GTPases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Complex complexes: signaling at the TCR.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Signal transduction by lymphocyte antigen receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2 mobilization through distinct pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Identification by electrospray ionization mass spectrometry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4 CD8 thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

A functional T-cell receptor signaling pathway is required for p95vav activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196311

Proto-vav and gene expression.

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084/JEM.185.10.1877

Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084/JEM.185.10.1877

21 January 2018

Identifiers

DOI

10.1084/JEM.185.10.1877

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

9151714

1 reference