CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. (Q36370844)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163562 AND SRC:MED&resulttype=core&format=json

11 November 2019

title

CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly (English)

1 reference

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11 November 2019

0 references

7

1 reference

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11 November 2019

Robert Rottapel

8

1 reference

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11 November 2019

James R. Woodgett

9

1 reference

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11 November 2019

Pamela Ohashi

10

1 reference

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11 November 2019

author name string

Russell G Jones

1

1 reference

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11 November 2019

Alisha R Elford

2

1 reference

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11 November 2019

Michael J Parsons

3

1 reference

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11 November 2019

Linda Wu

4

1 reference

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11 November 2019

Connie M Krawczyk

5

1 reference

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11 November 2019

Wen-Chen Yeh

6

1 reference

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11 November 2019

language of work or name

English

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publication date

1 August 2002

1 reference

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Journal of Experimental Medicine

11 November 2019

published in

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11 November 2019

volume

196

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11 November 2019

issue

3

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11 November 2019

page(s)

335-348

1 reference

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T-cell regulation by CD28 and CTLA-4.

11 November 2019

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Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

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Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

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Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes

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Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

30 September 2017

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Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling.

30 September 2017

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Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

30 September 2017

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30 September 2017

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30 September 2017

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

30 September 2017

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Two CD95 (APO-1/Fas) signaling pathways

30 September 2017

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Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice

30 September 2017

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Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

30 September 2017

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Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

30 September 2017

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

30 September 2017

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Inhibition of death receptor signals by cellular FLIP

30 September 2017

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

30 September 2017

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

30 September 2017

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Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

30 September 2017

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CD28/B7 system of T cell costimulation

30 September 2017

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

30 September 2017

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Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

30 September 2017

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Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

30 September 2017

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Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

30 September 2017

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CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

30 September 2017

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Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

30 September 2017

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

30 September 2017

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Fas and Fas ligand: lpr and gld mutations

30 September 2017

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Programmed cell death and extrathymic reduction of Vβ8 CD4 T cells in mice tolerant to Staphylococcus aureus enterotoxin B

30 September 2017

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Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo

30 September 2017

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Mature T cell reactivity altered by peptide agonist that induces positive selection

28 June 2018

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Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation

28 June 2018

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Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

28 June 2018

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Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

28 June 2018

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Inhibition of JNK activation through NF-kappaB target genes

27 July 2018

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Akt protects mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis through NK-kappa B activation

21 September 2018

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Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

21 September 2018

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Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

21 September 2018

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A point mutation in CD28 distinguishes proliferative signals from survival signals

21 September 2018

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Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells.

21 September 2018

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TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions

21 September 2018

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Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

21 September 2018

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Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells

21 September 2018

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FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.

21 September 2018

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Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 September 2018

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Costimulation blockade promotes the apoptotic death of graft-infiltrating T cells and prolongs survival of hepatic allografts from FLT3L-treated donors

21 September 2018

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CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation

21 October 2018

1 reference

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Analysis of the CD4 coreceptor and activation-induced costimulatory molecules in antigen-mediated mature T lymphocyte death

21 October 2018

1 reference

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Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

21 October 2018

1 reference

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Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20020307

CD28 can promote T cell survival through a phosphatidylinositol 3-kinase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20020307

A role for CD95 ligand in preventing graft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20020307

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

21 January 2018

1 reference

12 December 2020

CD28 costimulation inhibits TCR-induced apoptosis during a primary T cell response

1 reference

12 December 2020

The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

1 reference

12 December 2020

Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

1 reference

12 December 2020

Impaired Fas response and autoimmunity in Pten /- mice

1 reference

12 December 2020

Selective up-regulation of phosphatidylinositol 3'-kinase activity in Th2 cells inhibits caspase-8 cleavage at the death-inducing complex: a mechanism for Th2 resistance from Fas-mediated apoptosis

1 reference

12 December 2020

Immune down-regulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1)

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20020307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163562 AND SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163562 AND SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

12163562

1 reference