Immune cell migration in inflammation: present and future therapeutic targets (Q36348737)

13 August 2017

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title

Immune cell migration in inflammation: present and future therapeutic targets (English)

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13 August 2017

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3

Ulrich H von Andrian

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13 August 2017

Andrew D Luster

1

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13 August 2017

Ronen Alon

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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13 August 2017

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13 August 2017

volume

6

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13 August 2017

issue

12

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13 August 2017

page(s)

1182-1190

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Chemokines — Chemotactic Cytokines That Mediate Inflammation

13 August 2017

cites work

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7 January 2021

Leukocyte and endothelial cell adhesion molecules as targets for therapeutic interventions in inflammatory disease

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7 January 2021

Targeting leukocyte integrins in human diseases

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7 January 2021

Travellers in many guises: the origins and destinations of dendritic cells

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Immunobiology of dendritic cells

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In vivo depletion of CD11c dendritic cells abrogates priming of CD8 T cells by exogenous cell-associated antigens

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T-Cell Function and Migration — Two Sides of the Same Coin

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Acquisition of selectin binding and peripheral homing properties by CD4( ) and CD8( ) T cells

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Migratory properties of naive, effector, and memory CD8( ) T cells

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Central memory and effector memory T cell subsets: function, generation, and maintenance

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Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues

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Homing phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs.

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Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

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P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

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CCR7 expression and memory T cell diversity in humans

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Lineage relationship and protective immunity of memory CD8 T cell subsets

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Selectins: lectins that initiate cell adhesion under flow

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Ligands for L-selectin: homing, inflammation, and beyond

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P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules

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L-selectin shedding regulates leukocyte recruitment

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Integrin avidity regulation: are changes in affinity and conformation underemphasized?

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Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

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Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium

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Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

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Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

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7 January 2021

Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels

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Integration of inflammatory signals by rolling neutrophils

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7 January 2021

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

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7 January 2021

Absence of the Endothelial Oxidase AOC3 Leads to Abnormal Leukocyte Traffic In Vivo

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7 January 2021

Intracellular signalling controlling integrin activation in lymphocytes

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Bimolecular complex between rolling and firm adhesion receptors required for cell arrest; CD44 association with VLA-4 in T cell extravasation

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Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines

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Therapeutic antagonists and the conformational regulation of the beta2 integrins

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The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.

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Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor

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RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.

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7 January 2021

Rapid leukocyte integrin activation by chemokines

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7 January 2021

Leukocyte arrest during cytokine-dependent inflammation in vivo

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Rolling of Th1 cells via P-selectin glycoprotein ligand-1 stimulates LFA-1-mediated cell binding to ICAM-1.

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CXCR2- and E-selectin-induced neutrophil arrest during inflammation in vivo

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Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

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Regulation of endothelial cell contacts during leukocyte extravasation

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Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

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Membranes as messengers in T cell adhesion signaling

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Role of the cytoskeleton during leukocyte responses

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Phosphoinositide 3-kinase in disease: timing, location, and scaffolding

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Neutrophils Emigrate from Venules by a Transendothelial Cell Pathway in Response to FMLP

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Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.

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A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them

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7 January 2021

PECAM-1 (CD31) homophilic interaction up-regulates alpha6beta1 on transmigrated neutrophils in vivo and plays a functional role in the ability of alpha6 integrins to mediate leukocyte migration through the perivascular basement membrane

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7 January 2021

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

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7 January 2021

Blockade of alpha6 integrin inhibits IL-1beta- but not TNF-alpha-induced neutrophil transmigration in vivo

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7 January 2021

The collagen binding alpha1beta1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection

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7 January 2021

Macromolecular organization of basement membranes

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7 January 2021

Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis

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7 January 2021

Extracellular matrix remodelling: the role of matrix metalloproteinases

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7 January 2021

Glycosaminoglycans and the regulation of allergic inflammation

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7 January 2021

The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent

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7 January 2021

Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2

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7 January 2021

Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses

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7 January 2021

Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases

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7 January 2021

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds

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7 January 2021

Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8.

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Essential involvement of interleukin-8 (IL-8) in acute inflammation

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Reversing systemic inflammatory response syndrome with chemokine receptor pepducins

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7 January 2021

Natalizumab for active Crohn's disease

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7 January 2021

A controlled trial of natalizumab for relapsing multiple sclerosis

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7 January 2021

Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin

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7 January 2021

Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity

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7 January 2021

CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin

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7 January 2021

Role of chemokines in the development of secondary and tertiary lymphoid tissues

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7 January 2021

Blood monocytes consist of two principal subsets with distinct migratory properties

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7 January 2021

Fractalkine preferentially mediates arrest and migration of CD16 monocytes

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7 January 2021

Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

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7 January 2021

Targeting monocyte recruitment in CNS autoimmune disease

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7 January 2021

An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

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7 January 2021

The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

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7 January 2021

CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation

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7 January 2021

Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling.

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7 January 2021

Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation

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7 January 2021

T-cell trafficking in asthma: lipid mediators grease the way.

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7 January 2021

Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment

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7 January 2021

Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues

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7 January 2021

Colonic epithelial cells are a major site of macrophage inflammatory protein 3alpha (MIP-3alpha) production in normal colon and inflammatory bowel disease

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7 January 2021

CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue.

1 reference

7 January 2021

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

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7 January 2021

Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics

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7 January 2021

Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

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7 January 2021

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

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7 January 2021

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

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7 January 2021

Identifiers

DOI

10.1038/NI1275

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13 August 2017

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