Protein translocation across biological membranes (Q36328629)

13 August 2017

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title

Protein translocation across biological membranes (English)

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13 August 2017

2

Randy Schekman

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13 August 2017

William Wickner

1

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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13 August 2017

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13 August 2017

volume

310

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13 August 2017

issue

5753

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13 August 2017

page(s)

1452-1456

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Import of proteins into mitochondria: precursor forms of the extramitochondrially made F1-ATPase subunits in yeast

13 August 2017

cites work

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Co-translocation of a Periplasmic Enzyme Complex by a Hitchhiker Mechanism through the Bacterial Tat Pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Identification and characterization of a membrane component essential for the translocation of nascent proteins across the membrane of the endoplasmic reticulum

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Synthesis and assembly of the membrane proteins in E. coli

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Inversion of the membrane topology of SecG coupled with SecA-dependent preprotein translocation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

ATP is essential for protein translocation into Escherichia coli membrane vesicles

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A common export pathway for proteins binding complex redox cofactors?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The E. coli ffh gene is necessary for viability and efficient protein export.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Import of stably folded proteins into peroxisomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Stepwise movement of preproteins in the process of translocation across the cytoplasmic membrane of Escherichia coli.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Peroxisome biogenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A conserved tripeptide sorts proteins to peroxisomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Empty site forms of the SRP54 and SR alpha GTPases mediate targeting of ribosome-nascent chain complexes to the endoplasmic reticulum

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Evaluating the oligomeric state of SecYEG in preprotein translocase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Machinery for protein sorting and assembly in the mitochondrial outer membrane

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The pas8 mutant of Pichia pastoris exhibits the peroxisomal protein import deficiencies of Zellweger syndrome cells--the PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Structural insight into the protein translocation channel

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Evolutionary conservation of biogenesis of beta-barrel membrane proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The purified E. coli integral membrane protein SecY/E is sufficient for reconstitution of SecA-dependent precursor protein translocation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Preferential Synthesis of Ferritin and Albumin by Different Populations of Liver Polysomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Post-translational transport into intact chloroplasts of a precursor to the small subunit of ribulose-1,5-bisphosphate carboxylase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Energetics of protein transport across biological membranes. a study of the thylakoid DeltapH-dependent/cpTat pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The protein import motor of mitochondria

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Escherichia coli YidC is a membrane insertase for Sec-independent proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A signal sequence is not sufficient to lead β-galactosidase out of the cytoplasm

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Contribution of the endoplasmic reticulum to peroxisome formation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Mechanisms of protein import and routing in chloroplasts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The human peroxisomal targeting signal receptor, Pex5p, is translocated into the peroxisomal matrix and recycled to the cytosol

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

E. coli mutant pleiotropically defective in the export of secreted proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

X-ray structure of a protein-conducting channel

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The protein import machinery of mitochondria

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Prepro-carboxypeptidase Y and a truncated form of pre-invertase, but not full-length pre-invertase, can be posttranslationally translocated across microsomal vesicle membranes from Saccharomyces cerevisiae

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The preprotein translocation channel of the outer membrane of mitochondria

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

An oligomeric protein is imported into peroxisomes in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

ERAD: the long road to destruction

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Vectorial discharge of peptides released by puromycin from attached ribosomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

In vitro translocation of bacterial proteins across the plasma membrane of Escherichia coli

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Synchronised transmembrane insertion and glycosylation of a nascent membrane protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Translocation of domains of nascent periplasmic proteins across the cytoplasmic membrane is independent of elongation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

In vitro synthesis of different categories of specific protein by membrane-bound and free ribosomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Bacterial leader peptidase, a membrane protein without a leader peptide, uses the same export pathway as pre-secretory proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Insertion into the mitochondrial inner membrane of a polytopic protein, the nuclear-encoded Oxa1p

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

The signal recognition particle in S. cerevisiae

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A membrane protein required for dislocation of misfolded proteins from the ER

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A novel signal recognition particle targets light-harvesting proteins to the thylakoid membranes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Controlled proteolysis of nascent polypeptides in rat liver cell fractions. II. Location of the polypeptides in rough microsomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Suppressor mutations that restore export of a protein with a defective signal sequence

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Inactivation of the endoplasmic reticulum protein translocation factor, Sec61p, or its homolog, Ssh1p, does not affect peroxisome biogenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Peroxisomal membrane fusion requires two AAA family ATPases, Pex1p and Pex6p

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1113752

Identifiers

DOI

10.1126/SCIENCE.1113752

1 reference

13 August 2017

1 reference