Glucocorticoids in T cell apoptosis and function. (Q36325611)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

review article

3 references

20 December 2020

3 October 2022

Glucocorticoids in T cell apoptosis and function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

20 December 2020

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

17 November 2019

2

1 reference

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9 January 2020

author name string

M J Herold

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

H M Reichardt

series ordinal

3

1 reference

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9 January 2020

language of work or name

1 reference

1 January 2006

6 references

12 October 2019

18 October 2019

17 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

20 December 2020

3 October 2022

Cellular and Molecular Life Sciences

6 references

12 October 2019

18 October 2019

17 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

20 December 2020

3 October 2022

63

1 reference

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9 January 2020

issue

1

1 reference

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9 January 2020

page(s)

60-72

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

Caspase-independent cell death

9 January 2020

cites work

1 reference

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Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes.

30 September 2017

1 reference

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The human glucocorticoid receptor: one gene, multiple proteins and diverse responses

30 September 2017

1 reference

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Glucocorticoid-induced apoptosis and glucocorticoid resistance in acute lymphoblastic leukemia.

30 September 2017

1 reference

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The role of BH3-only proteins in the immune system

30 September 2017

1 reference

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Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis

30 September 2017

1 reference

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Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates

30 September 2017

1 reference

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Autophagy: many paths to the same end.

30 September 2017

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Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA.

30 September 2017

1 reference

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Different roles for glucocorticoids in thymocyte homeostasis?

30 September 2017

1 reference

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The glucocorticoid-induced gene tdag8 encodes a pro-apoptotic G protein-coupled receptor whose activation promotes glucocorticoid-induced apoptosis

30 September 2017

1 reference

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Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions

30 September 2017

1 reference

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Immunomodulatory activities of glucocorticoids: insights from transgenesis and gene targeting

30 September 2017

1 reference

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Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

30 September 2017

1 reference

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Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death

30 September 2017

1 reference

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The pathophysiology of mitochondrial cell death

30 September 2017

1 reference

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Glucocorticoid regulation of the inflammatory response to injury

30 September 2017

1 reference

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Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth

30 September 2017

1 reference

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Phosphorylation of BCL-2 regulates ER Ca2 homeostasis and apoptosis.

30 September 2017

1 reference

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Molecular and cellular mechanisms of T cell development

30 September 2017

1 reference

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

30 September 2017

1 reference

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The CD95 type I/type II model

30 September 2017

1 reference

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

30 September 2017

1 reference

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Bad-deficient mice develop diffuse large B cell lymphoma

30 September 2017

1 reference

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Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

30 September 2017

1 reference

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Gene expression profile of human lymphoid CEM cells sensitive and resistant to glucocorticoid-evoked apoptosis

30 September 2017

1 reference

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Dexamethasone-induced Gene 2 (dig2) Is a Novel Pro-survival Stress Gene Induced Rapidly by Diverse Apoptotic Signals

30 September 2017

1 reference

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Apoptosis in the development and maintenance of the immune system

30 September 2017

1 reference

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Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis

30 September 2017

1 reference

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

30 September 2017

1 reference

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Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane

30 September 2017

1 reference

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Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

30 September 2017

1 reference

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Hydrogen peroxide as second messenger in lymphocyte activation

30 September 2017

1 reference

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Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice

30 September 2017

1 reference

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Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

30 September 2017

1 reference

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Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

30 September 2017

1 reference

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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

30 September 2017

1 reference

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Effects of altered glucocorticoid sensitivity in the T cell lineage on thymocyte and T cell homeostasis

30 September 2017

1 reference

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Neuroendocrine regulation of immunity

30 September 2017

1 reference

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Recent insights into the mechanism of glucocorticosteroid-induced apoptosis

30 September 2017

1 reference

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Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor

30 September 2017

1 reference

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The expanding role of mitochondria in apoptosis

30 September 2017

1 reference

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Glucocorticoid receptor activation of the I kappa B alpha promoter within chromatin

30 September 2017

1 reference

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

30 September 2017

1 reference

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Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

30 September 2017

1 reference

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

30 September 2017

1 reference

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Activation-induced cell death

30 September 2017

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

30 September 2017

1 reference

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Novel glucocorticoid receptor coactivator effector mechanisms

30 September 2017

1 reference

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

30 September 2017

1 reference

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Glucocorticoids and thymocyte development

30 September 2017

1 reference

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Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock

30 September 2017

1 reference

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The biochemistry of apoptosis

30 September 2017

1 reference

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Resetting of circadian time in peripheral tissues by glucocorticoid signaling

30 September 2017

1 reference

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Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling

30 September 2017

1 reference

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Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes

30 September 2017

1 reference

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

30 September 2017

1 reference

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Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire

30 September 2017

1 reference

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Glucocorticoid production in the murine thymus

30 September 2017

1 reference

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The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin

30 September 2017

1 reference

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

30 September 2017

1 reference

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

30 September 2017

1 reference

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Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.

30 September 2017

1 reference

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Paracrine glucocorticoid activity produced by mouse thymic epithelial cells

30 September 2017

1 reference

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Subcellular distribution and redistribution of Bcl-2 family proteins in human leukemia cells undergoing apoptosis

30 September 2017

1 reference

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The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

30 September 2017

1 reference

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Molecular characterization of mitochondrial apoptosis-inducing factor

30 September 2017

1 reference

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Bad can act as a key regulator of T cell apoptosis and T cell development.

30 September 2017

1 reference

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

30 September 2017

1 reference

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

30 September 2017

1 reference

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DNA binding of the glucocorticoid receptor is not essential for survival

30 September 2017

1 reference

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A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death

30 September 2017

1 reference

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Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription

30 September 2017

1 reference

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I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

30 September 2017

1 reference

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A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

30 September 2017

1 reference

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T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis

30 September 2017

1 reference

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

30 September 2017

1 reference

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

30 September 2017

1 reference

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Molecular chaperoning of steroid hormone receptors

30 September 2017

1 reference

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Steroid hormone receptors: many actors in search of a plot

30 September 2017

1 reference

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The nuclear receptor superfamily: the second decade

30 September 2017

1 reference

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

30 September 2017

1 reference

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Steroid production in the thymus: implications for thymocyte selection.

30 September 2017

1 reference

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A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

30 September 2017

1 reference

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Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of costimulated T cell responses by phorbol ester

30 September 2017

1 reference

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Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

30 September 2017

1 reference

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Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

30 September 2017

1 reference

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

30 September 2017

1 reference

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Primary structure and expression of a functional human glucocorticoid receptor cDNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Transcriptional cross-talk, the second mode of steroid hormone receptor action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

In Thymic Selection, Peptide Diversity Gives and Takes Away

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Do inducers of apoptosis trigger caspase-independent cell death?

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Serine protease inhibitor 2A is a protective factor for memory T cell development

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Resistance of single-positive thymocytes to glucocorticoid-induced apoptosis is mediated by CD28 signaling.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Cathepsin-B-dependent apoptosis triggered by antithymocyte globulins: a novel mechanism of T-cell depletion

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Critical function of T cell death-associated gene 8 in glucocorticoid-induced thymocyte apoptosis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Glucocorticoid-induced apoptosis of thymocytes: requirement of proteasome-dependent mitochondrial activity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

5'UTR sequences of the glucocorticoid receptor 1A transcript encode a peptide associated with translational regulation of the glucocorticoid receptor.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in a T cell hybridoma.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2792342

The costimulatory molecule B7 is expressed in the medullary region of the murine thymus

5 December 2018

1 reference

12 December 2020

Phosphorylation status modulates Bcl-2 function during glucocorticoid-induced apoptosis in T lymphocytes

1 reference

12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

12 December 2020

T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation

1 reference

12 December 2020

A primary role for K and Na efflux in the activation of apoptosis

1 reference

12 December 2020

Thymocyte Glucocorticoid Resistance Alters Positive Selection and Inhibits Autoimmunity and Lymphoproliferative Disease in MRL-Mice

1 reference

12 December 2020

Glucocorticoid-induced thymocyte apoptosis: protease-dependent activation of cell shrinkage and DNA degradation

1 reference

12 December 2020

Dexamethasone-induced thymocyte apoptosis: apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases

1 reference

12 December 2020

Transcription activation of the tyrosine aminotransferase gene by glucocorticoids and cAMP in primary hepatocytes

1 reference

12 December 2020

Steroid sensitivity of thymocyte subpopulations during intrathymic differentiation. Effects of 17 beta-estradiol and dexamethasone on subsets expressing T cell antigen receptor or IL-2 receptor

1 reference

12 December 2020

Glucocorticoid regulation of transcription of the c-myc cellular protooncogene in P1798 cells

1 reference

12 December 2020

bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation

1 reference

12 December 2020

Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes

1 reference

12 December 2020

A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development

1 reference

12 December 2020

Characterization of mice deficient in interleukin-1 beta converting enzyme

1 reference

12 December 2020

Substrate specificities of caspase family proteases

1 reference

12 December 2020

Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo

1 reference

12 December 2020

Dexamethasone-induced apoptosis of thymocytes: role of glucocorticoid receptor-associated Src kinase and caspase-8 activation

1 reference

12 December 2020

Mutually antagonistic signals regulate selection of the T cell repertoire

1 reference

12 December 2020

Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-xL

1 reference

12 December 2020

Delineation of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes

1 reference

12 December 2020

Mammary gland development and lactation are controlled by different glucocorticoid receptor activities

1 reference

12 December 2020

10.1007/S00018-005-5390-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16314919 AND SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

16314919

1 reference