Sildenafil Protects against Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Porcine Model: Possible Role of the Renin-Angiotensin System (Q36324656)

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English	Sildenafil Protects against Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Porcine Model: Possible Role of the Renin-Angiotensin System	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Sildenafil Protects against Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Porcine Model: Possible Role of the Renin-Angiotensin System (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

reperfusion injury

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Guoxing Wang

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Qian Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wei Yuan

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Junyuan Wu

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Chunsheng Li

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

12 November 2015

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

International Journal of Molecular Sciences

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Europe PubMed Central

PMC publication ID

13 August 2017

16

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

27015-27031

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 November 2015

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April 2022 Public Data File from Crossref

copyright status

0 references

The effects of phosphodiesterase-5 inhibitor sildenafil against post-resuscitation myocardial and intestinal microcirculatory dysfunction by attenuating apoptosis and regulating microRNAs expression: essential role of nitric oxide syntheses signalin

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Chronic Inhibition of PDE5 Limits Pro-Inflammatory Monocyte-Macrophage Polarization in Streptozotocin-Induced Diabetic Mice

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Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes

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30 September 2017

Hydrogen sulfide inhalation decreases early blood-brain barrier permeability and brain edema induced by cardiac arrest and resuscitation

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30 September 2017

The protective effects of a phosphodiesterase 5 inhibitor, sildenafil, on postresuscitation cardiac dysfunction of cardiac arrest: metabolic evidence from microdialysis

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30 September 2017

Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest: a statement for healthcare professionals from a task force of the International Liaison Comm

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30 September 2017

Is chronic inhibition of phosphodiesterase type 5 cardioprotective and safe? A meta-analysis of randomized controlled trials

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30 September 2017

Sildenafil attenuates inflammation and oxidative stress in pelvic ganglia neurons after bilateral cavernosal nerve damage

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Inhibition of phosphodiesterase 5 restores endothelial function in renovascular hypertension.

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30 September 2017

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia.

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30 September 2017

Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

30 September 2017

Effect of Renin-Angiotensin system inhibition on cardiovascular events in older hypertensive patients with metabolic syndrome

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30 September 2017

Combination of epinephrine with esmolol attenuates post-resuscitation myocardial dysfunction in a porcine model of cardiac arrest

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30 September 2017

Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis

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30 September 2017

Nitric oxide inhibits the expression of AT1 receptors in neurons

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30 September 2017

Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death.

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30 September 2017

Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury.

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30 September 2017

Arginase inhibition mediates cardioprotection during ischaemia-reperfusion

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30 September 2017

ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.

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30 September 2017

Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide

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30 September 2017

Physiology of local renin-angiotensin systems.

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30 September 2017

Sildenafil citrate therapy for pulmonary arterial hypertension

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

30 September 2017

Importance of continuous chest compressions during cardiopulmonary resuscitation: improved outcome during a simulated single lay-rescuer scenario

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30 September 2017

Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group

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30 September 2017

Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors

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30 September 2017

Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity

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29 June 2018

Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

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Estimating effectiveness of cardiac arrest interventions: a logistic regression survival model

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29 June 2018

Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling.

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22 September 2018

Intracellular NAMPT-NAD -SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

22 September 2018

Caspase-3-mediated splenic lymphocyte apoptosis in a porcine model of cardiac arrest.

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22 September 2018

Vascular smooth muscle cell apoptosis is an early trigger for hypothyroid atherosclerosis

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Contribution of calpain to myoglobin efflux from cardiomyocytes during ischaemia and after reperfusion in anaesthetized rats

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22 September 2018

The heart is better protected against myocardial infarction in the fed state compared to the fasted state.

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22 September 2018

Valsartan attenuates oxidative stress and NF-κB activation and reduces myocardial apoptosis after ischemia and reperfusion

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22 September 2018

Sildenafil and diastolic dysfunction after acute myocardial infarction in patients with preserved ejection fraction: the Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (SIDAMI) trial

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22 September 2018

Comparison of shock-first strategy and cardiopulmonary resuscitation-first strategy in a porcine model of prolonged cardiac arrest

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22 September 2018

PDE5 inhibition with sildenafil improves left ventricular diastolic function, cardiac geometry, and clinical status in patients with stable systolic heart failure: results of a 1-year, prospective, randomized, placebo-controlled study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

22 September 2018

Effect of continuous compressions and 30:2 cardiopulmonary resuscitation on global ventilation/perfusion values during resuscitation in a porcine model

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22 September 2018

Comparison of the efficacy of nifekalant and amiodarone in a porcine model of cardiac arrest

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22 September 2018

Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice

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22 September 2018

Atorvastatin but not elocalcitol increases sildenafil responsiveness in spontaneously hypertensive rats by regulating the RhoA/ROCK pathway.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

22 September 2018

Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway.

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22 September 2018

Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling.

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22 September 2018

Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits

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22 September 2018

Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection

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22 September 2018

Cardioprotection with sildenafil, a selective inhibitor of cyclic 3',5'-monophosphate-specific phosphodiesterase 5.

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22 September 2018

Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusion

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22 September 2018

Nitric oxide regulates angiotensin II receptors in vascular smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661868

22 September 2018

Downregulation of Angiotensin II Type 1 Receptor Gene Transcription by Nitric Oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of angiotensin II receptor expression by nitric oxide in rat adrenal gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide inhibits angiotensin II-induced activation of the calcium-sensitive tyrosine kinase proline-rich tyrosine kinase 2 without affecting epidermal growth factor receptor transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic Inhibition of cGMP Phosphodiesterase 5A Improves Diabetic Cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade prevent cardiac remodeling in pigs after myocardial infarction: role of tissue angiotensin II

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ANG II receptors, c-myc, and c-jun in myocytes after myocardial infarction and ventricular failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/26569234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/IJMS161126010

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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