Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice (Q36302763)

13 August 2017

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice (English)

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13 August 2017

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Kevin M Nickerson

1

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Mark Shlomchik

series ordinal

4

object named as

Mark J Shlomchik

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13 August 2017

Yujuan Wang

2

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13 August 2017

Sheldon Bastacky

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

9 March 2017

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13 August 2017

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13 August 2017

12

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13 August 2017

3

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13 August 2017

e0173471

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Creative Commons Attribution 4.0 International

13 August 2017

start time

9 March 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Dendritic Cells Regulate Extrafollicular Autoreactive B Cells via T Cells Expressing Fas and Fas Ligand.

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TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.

30 September 2017

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Toll-like receptors and chronic inflammation in rheumatic diseases: new developments

30 September 2017

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Genetics and novel aspects of therapies in systemic lupus erythematosus.

30 September 2017

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Double negative (DN) αβ T cells: misperception and overdue recognition

30 September 2017

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B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.

30 September 2017

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Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

30 September 2017

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A long-awaited merger of the pathways mediating host defence and programmed cell death.

30 September 2017

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Autoimmune lymphoproliferative syndrome: an update and review of the literature

30 September 2017

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Activation of rheumatoid factor-specific B cells is antigen dependent and occurs preferentially outside of germinal centers in the lupus-prone NZM2410 mouse model

30 September 2017

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Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation

30 September 2017

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TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice

30 September 2017

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Contributions of B cells to lupus pathogenesis

30 September 2017

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B-lymphocyte tolerance and effector function in immunity and autoimmunity

30 September 2017

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Expression of an anti-RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN-I expression

30 September 2017

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Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice

30 September 2017

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Life in the Fas lane: differential outcomes of Fas signaling

30 September 2017

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Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus

30 September 2017

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Exacerbated autoimmunity in the absence of TLR9 in MRL.Fas(lpr) mice depends on Ifnar1

30 September 2017

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TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation

30 September 2017

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B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice

30 September 2017

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Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity

30 September 2017

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TLR7 and TLR9 in SLE: when sensing self goes wrong

30 September 2017

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Integration of B cell responses through Toll-like receptors and antigen receptors

30 September 2017

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30 September 2017

B cells and autoimmunity

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CD3 CD4−CD8− (double negative) T cells: Saviours or villains of the immune response?

30 September 2017

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Facultative role for T cells in extrafollicular Toll-like receptor-dependent autoreactive B-cell responses in vivo.

30 September 2017

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A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formation

30 September 2017

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TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

30 September 2017

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The many roles of FAS receptor signaling in the immune system

30 September 2017

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TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus

30 September 2017

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Programmed death ligand 1 regulates a critical checkpoint for autoimmune myocarditis and pneumonitis in MRL mice

30 September 2017

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Sites and stages of autoreactive B cell activation and regulation.

30 September 2017

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Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Monocytosis in the BXSB model for systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Presence of anti-Sm reactivity in autoimmune mouse strains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Cutting edge: Type I IFN drives emergency myelopoiesis and peripheral myeloid expansion during chronic TLR7 signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Anti-chromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

TLR9 in peritoneal B-1b cells is essential for production of protective self-reactive IgM to control Th17 cells and severe autoimmunity.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344451

TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy

22 September 2018

1 reference

12 December 2020

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

1 reference

12 December 2020

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

1 reference

12 December 2020

Pathogenesis of autoimmunity in αβ T cell-deficient lupus-prone mice

1 reference

12 December 2020

Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE

1 reference

12 December 2020

Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus

1 reference

12 December 2020

Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus

1 reference

12 December 2020

Induction of various autoantibodies by mutant gene lpr in several strains of mice

1 reference

12 December 2020

Evolution of autoantibody responses via somatic hypermutation outside of germinal centers

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0173471

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

28278279

1 reference