Death receptors and caspases: role in lymphocyte proliferation, cell death, and autoimmunity (Q36290306)

13 August 2017

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title

Death receptors and caspases: role in lymphocyte proliferation, cell death, and autoimmunity (English)

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13 August 2017

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Dieter Adam

2

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Ottmar Janssen

object named as

Ottmar Janssen

series ordinal

3

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author name string

Sabine Adam-Klages

series ordinal

1

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13 August 2017

Dieter Kabelitz

series ordinal

4

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13 August 2017

publication date

1 January 2005

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13 August 2017

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13 August 2017

volume

33

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13 August 2017

issue

2

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13 August 2017

page(s)

149-166

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Caspases and caspase inhibitors

13 August 2017

cites work

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12 December 2020

Caspase-independent cell death in T lymphocytes

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12 December 2020

Complete loss of Fas ligand gene causes massive lymphoproliferation and early death, indicating a residual activity of gld allele

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12 December 2020

BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth

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12 December 2020

Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways

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12 December 2020

Apoptotic and necrotic cell death induced by death domain receptors.

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12 December 2020

The dual functions of fas ligand in the regulation of peripheral CD8 and CD4 T cells

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12 December 2020

Structures of the extracellular domain of the type I tumor necrosis factor receptor

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12 December 2020

Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

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12 December 2020

Cell-death signaling and human disease

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12 December 2020

Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation

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12 December 2020

Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons

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12 December 2020

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

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12 December 2020

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

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12 December 2020

Inhibition of caspase or FADD function blocks proliferation but not MAP kinase-activation and interleukin-2-production during primary stimulation of T cells

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12 December 2020

Chronic lymphadenopathy simulating malignant lymphoma

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12 December 2020

A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts

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12 December 2020

T-cell activation and the development of an apoptosis-resistant CD45RO T-cell population

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12 December 2020

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

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12 December 2020

The requirements for Fas-associated death domain signaling in mature T cell activation and survival

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12 December 2020

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

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12 December 2020

The CD95(APO-1/Fas) DISC and beyond

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12 December 2020

Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice

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12 December 2020

Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice

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12 December 2020

Autoimmune lymphoproliferative syndrome.

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12 December 2020

Considering Fas ligand as a target for therapy

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12 December 2020

A role for FADD in T cell activation and development

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12 December 2020

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

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12 December 2020

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

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12 December 2020

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

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12 December 2020

Proinflammatory cytokines

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12 December 2020

Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.

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12 December 2020

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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12 December 2020

Chimeric tumor necrosis factor receptors with constitutive signaling activity

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12 December 2020

Caspase activation is required for terminal erythroid differentiation

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12 December 2020

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

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12 December 2020

Activation of the NF-kappaB pathway by caspase 8 and its homologs

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12 December 2020

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

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12 December 2020

Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.

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12 December 2020

A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region

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12 December 2020

Signalling pathways of the TNF superfamily: a double-edged sword

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12 December 2020

Caspase-3-mediated Cleavage of Protein Kinase C θ in Induction of Apoptosis

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12 December 2020

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12 December 2020

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

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12 December 2020

p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice

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12 December 2020

A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease

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12 December 2020

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

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12 December 2020

Caspase inhibition blocks human T cell proliferation by suppressing appropriate regulation of IL-2, CD25, and cell cycle-associated proteins

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12 December 2020

A novel domain within the 55 kd TNF receptor signals cell death

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12 December 2020

Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

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12 December 2020

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

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12 December 2020

Many cuts to ruin: a comprehensive update of caspase substrates

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12 December 2020

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

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12 December 2020

Regulation of lymphocyte proliferation and death by FLIP.

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12 December 2020

Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages

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12 December 2020

The molecular architecture of the TNF superfamily

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12 December 2020

The TNF and TNF receptor superfamilies: integrating mammalian biology

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12 December 2020

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

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12 December 2020

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

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12 December 2020

The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations

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12 December 2020

Effects of a dominant interfering mutant of FADD on signal transduction in activated T cells

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12 December 2020

Activation of caspase-3-like enzymes in non-apoptotic T cells

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12 December 2020

Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival

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12 December 2020

Four deaths and a funeral: from caspases to alternative mechanisms.

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12 December 2020

Fas transduces activation signals in normal human T lymphocytes

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12 December 2020

CD95 ligand--death factor and costimulatory molecule?

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12 December 2020

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

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12 December 2020

A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells

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12 December 2020

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

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12 December 2020

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

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12 December 2020

Protein kinase Ctheta: a new essential superstar on the T-cell stage

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12 December 2020

Caspase activation is required for T cell proliferation

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12 December 2020

Autoimmune lymphoproliferative syndrome

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12 December 2020

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

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12 December 2020

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

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12 December 2020

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

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12 December 2020

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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12 December 2020

The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis

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12 December 2020

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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12 December 2020

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

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12 December 2020

T cell-specific FADD-deficient mice: FADD is required for early T cell development

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12 December 2020

Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation

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12 December 2020

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

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12 December 2020

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

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12 December 2020

The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane

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12 December 2020

Differential modulation of interleukin-2-and interleukin-4-mediated early activation of normal human B lymphocytes by the caspase inhibitor zVAD-fmk.

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12 December 2020

Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia

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12 December 2020

Non-apoptotic Fas signaling.

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12 December 2020

Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity

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12 December 2020

How do tumor necrosis factor receptors work?

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12 December 2020

Cross-linking of the p55 tumor necrosis factor receptor cytoplasmic domain by a dimeric ligand induces nuclear factor-kappa B and mediates cell death

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12 December 2020

Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance

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12 December 2020

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

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12 December 2020

Mutation in fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptors

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12 December 2020

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

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12 December 2020

Apoptosis signaling in lymphocytes.

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12 December 2020

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

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12 December 2020

Signaling by the TNF receptor superfamily and T cell homeostasis

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12 December 2020

Specific involvement of caspases in the differentiation of monocytes into macrophages

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12 December 2020

Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP

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12 December 2020

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease

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12 December 2020

FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery

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12 December 2020

Differential requirement of caspases during naive T cell proliferation

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12 December 2020

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

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12 December 2020

Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations

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12 December 2020

gld/gld mice are unable to express a functional ligand for Fas.

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12 December 2020

Caspase-8 serves both apoptotic and nonapoptotic roles

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12 December 2020

Transcriptional regulation of the IL-2 gene

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12 December 2020

Caspases: more than just killers?

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12 December 2020

Enhanced and accelerated lymphoproliferation in Fas-null mice

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12 December 2020

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

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12 December 2020

Caspase activity is required for stimulated B lymphocytes to enter the cell cycle

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12 December 2020

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

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12 December 2020

Activation of NF-kappaB by FADD, Casper, and caspase-8.

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12 December 2020

Species-specific differences in the usage of several caspase substrates

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12 December 2020

Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.

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12 December 2020

Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase

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12 December 2020

Death receptors: signaling and modulation

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12 December 2020

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

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12 December 2020

Identifiers

DOI

10.1385/IR:33:2:149

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Dimensions Publication ID

13 August 2017

1001023478

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