GATA4 and GATA6 control mouse pancreas organogenesis. (Q36290293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23006330 AND SRC:MED&resulttype=core&format=json

8 March 2020

title

GATA4 and GATA6 control mouse pancreas organogenesis (English)

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8 March 2020

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4

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8 March 2020

Anabel Rojas

5

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8 March 2020

author name string

Manuel Carrasco

1

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8 March 2020

Irene Delgado

2

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8 March 2020

Bernat Soria

3

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8 March 2020

language of work or name

English

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publication date

24 September 2012

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Journal of Clinical Investigation

8 March 2020

published in

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8 March 2020

volume

122

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8 March 2020

issue

10

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8 March 2020

page(s)

3504-3515

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Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

8 March 2020

cites work

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GATA6 haploinsufficiency causes pancreatic agenesis in humans

30 September 2017

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Pancreas organogenesis: From bud to plexus to gland

30 September 2017

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GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice

30 September 2017

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Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer

30 September 2017

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GATA Switches as Developmental Drivers

30 September 2017

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Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

30 September 2017

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30 September 2017

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Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

30 September 2017

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Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood

30 September 2017

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GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.

30 September 2017

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Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

30 September 2017

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Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development

30 September 2017

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An illustrated review of early pancreas development in the mouse.

30 September 2017

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Development of the mammalian liver and ventral pancreas is dependent on GATA4.

30 September 2017

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Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression

30 September 2017

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SOX9 is required for maintenance of the pancreatic progenitor cell pool

30 September 2017

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Gata6 is an important regulator of mouse pancreas development

30 September 2017

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Generation of mice harbouring a conditional loss-of-function allele of Gata6.

30 September 2017

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Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element

30 September 2017

1 reference

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Mutations in PTF1A cause pancreatic and cerebellar agenesis

30 September 2017

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Transcription factor GATA-6 is expressed in the endocrine and GATA-4 in the exocrine pancreas

30 September 2017

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HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo

30 September 2017

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

30 September 2017

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Conserved transcriptional regulatory domains of the pdx-1 gene

30 September 2017

1 reference

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GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

30 September 2017

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The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

30 September 2017

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30 September 2017

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Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6

30 September 2017

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Direct evidence for the pancreatic lineage: NGN3 cells are islet progenitors and are distinct from duct progenitors

30 September 2017

1 reference

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A new mathematical model for relative quantification in real-time RT-PCR

30 September 2017

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A pancreatic beta -cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta ), HNF-1alpha, and SPs transcription factors

30 September 2017

1 reference

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A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart

30 September 2017

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The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.

30 September 2017

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Functional conservation of regulatory elements in the pdx-1 gene: PDX-1 and hepatocyte nuclear factor 3beta transcription factors mediate beta-cell-specific expression

30 September 2017

1 reference

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The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Distinct gene expression programs function in progenitor and mature islet cells.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

GATA transcription factors in congenital heart defects: a commentary on a novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

A novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

A multipotent progenitor domain guides pancreatic organogenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo

22 September 2018

1 reference

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The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites

22 September 2018

1 reference

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Developmental expression of the homeodomain protein IDX-1 in mice transgenic for an IDX-1 promoter/lacZ transcriptional reporter.

22 September 2018

1 reference

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The transcription factor GATA6 is essential for early extraembryonic development.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

IPF1, a homeodomain protein with a dual function in pancreas development.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461915

The role of hepatic nuclear factor 1 alpha and PDX-1 in transcriptional regulation of the pdx-1 gene

5 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23006330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23006330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI63240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23006330 AND SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23006330 AND SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

23006330

1 reference