Therapeutics of hearing loss: expectations vs reality (Q36281581)

13 August 2017

1 reference

title

Therapeutics of hearing loss: expectations vs reality (English)

1 reference

13 August 2017

1 reference

Karen B Avraham

2

0 references

author name string

Orna Atar

series ordinal

1

1 reference

13 August 2017

publication date

1 October 2005

1 reference

13 August 2017

1 reference

13 August 2017

volume

10

1 reference

13 August 2017

issue

19

1 reference

13 August 2017

page(s)

1323-1330

1 reference

13 August 2017

cites work

The genetics of deafness

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

PROFOUND CHILDHOOD DEAFNESS.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Hearing and hair cells are protected by adenoviral gene therapy with TGF-β1 and GDNF

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Brain-derived neurotrophic factor gene therapy prevents spiral ganglion degeneration after hair cell loss

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Effect of transgenic GDNF expression on gentamicin-induced cochlear and vestibular toxicity

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Reduction of noise-induced hearing loss using L-NAC and salicylate in the chinchilla

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

M40403, a superoxide dismutase mimetic, protects cochlear hair cells from gentamicin, but not cisplatin toxicity

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Blockade of c-Jun N-terminal kinase pathway attenuates gentamicin-induced cochlear and vestibular hair cell death

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Critical signaling events during the aminoglycoside-induced death of sensory hair cells in vitro

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

The expression of apoptosis-related proteins in the aged cochlea of Mongolian gerbils

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Deafness due to degeneration of cochlear neurons in caspase-3-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Caspase-3-deficiency induces hyperplasia of supporting cells and degeneration of sensory cells resulting in the hearing loss

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Math1: an essential gene for the generation of inner ear hair cells

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Cell-cycle inhibitors: three families united by a common cause

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Mouse models for human deafness: current tools for new fashions

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Nonviral vectors in the new millennium: delivery barriers in gene transfer

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Cationic liposome mediated transgene expression in the guinea pig cochlea

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Gene expression in the mammalian cochlea: a study of multiple vector systems.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

A surgical approach appropriate for targeted cochlear gene therapy in the mouse

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Rapid renewal of auditory hair bundles

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Transgene expression in the guinea pig cochlea mediated by a lentivirus-derived gene transfer vector

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Adenoviral-mediated gene transfer into guinea pig cochlear cells in vivo

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Transgene expression in mature guinea pig cochlear cells in vitro

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Cochlear gene therapy

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

A modified adenovirus can transfect cochlear hair cells in vivo without compromising cochlear function

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Progress and problems with the use of viral vectors for gene therapy

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Morphology of auditory hair cells in guinea pig cochlea after transgene expression

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

A glucocorticoid reduces adverse effects of adenovirus vectors in the cochlea

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Adenoviral and adeno-associated viral vector mediated gene transfer in the guinea pig cochlea

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Specific and efficient transduction of Cochlear inner hair cells with recombinant adeno-associated virus type 3 vector

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

A novel bovine virus efficiently transduces inner ear neuroepithelial cells

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

A specific promoter of the sensory cells of the inner ear defined by transgenesis

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Fate of neural stem cells grafted into injured inner ears of mice.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Pluripotent stem cells from the adult mouse inner ear.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Generation of hair cells by stepwise differentiation of embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Proliferative generation of mammalian auditory hair cells in culture

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Stem cells in adult tissues

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Trophic support of mouse inner ear by neural stem cell transplantation.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Mouse models for deafness: lessons for the human inner ear and hearing loss

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

The role of mouse mutants in the identification of human hereditary hearing loss genes

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

A novel technique for inducing local inner ear damage

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

In vitro and in vivo suppression of GJB2 expression by RNA interference.

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Silence of the transcripts: RNA interference in medicine

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(05)03618-4

7 January 2021

10.1016/S1359-6446(05)03618-4

Identifiers

DOI

1 reference

13 August 2017

1 reference