Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages. (Q36281294)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26438793 AND SRC:MED&resulttype=core&format=json

26 February 2020

title

Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages (English)

1 reference

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26 February 2020

0 references

1 reference

2

1 reference

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26 February 2020

Carlos Henrique Serezani

8

1 reference

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26 February 2020

author name string

Sebastian E Carrasco

1

1 reference

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26 February 2020

Youyun Yang

3

1 reference

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26 February 2020

Stephanie L Brandt

4

1 reference

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26 February 2020

Hongxia Li

5

1 reference

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26 February 2020

George E Sandusky

6

1 reference

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26 February 2020

Keith W Condon

7

1 reference

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26 February 2020

X Frank Yang

9

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26 February 2020

language of work or name

English

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publication date

5 October 2015

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26 February 2020

published in

Infection and Immunity

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26 February 2020

volume

83

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26 February 2020

issue

12

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26 February 2020

page(s)

4848-4860

1 reference

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Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes

26 February 2020

cites work

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Identification of residues within ligand-binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment.

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30 September 2017

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30 September 2017

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30 September 2017

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Treatment of mice with the neutrophil-depleting antibody RB6-8C5 results in early development of experimental lyme arthritis via the recruitment of Gr-1- polymorphonuclear leukocyte-like cells

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Activation of natural killer cells in arthritis-susceptible but not arthritis-resistant mouse strains following Borrelia burgdorferi infection.

30 September 2017

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30 September 2017

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Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC

30 September 2017

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30 September 2017

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Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine

30 September 2017

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Borrelia burgdorferi infection and immunity in mice deficient in the fifth component of complement.

30 September 2017

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Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

30 September 2017

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Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice

30 September 2017

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Induction of an outer surface protein on Borrelia burgdorferi during tick feeding

30 September 2017

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Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete

30 September 2017

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F4/80, a monoclonal antibody directed specifically against the mouse macrophage

30 September 2017

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30 September 2017

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The HL60 cell line: a model system for studying human myeloid cell differentiation

30 September 2017

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Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit

30 September 2017

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Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli

30 September 2017

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Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice

30 September 2017

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Morphology of Borrelia burgdorferi: structural patterns of cultured borreliae in relation to staining methods

30 September 2017

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DNA analysis of Borrelia burgdorferi NCH-1, the first northcentral U.S. human Lyme disease isolate

30 September 2017

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Coiling phagocytosis is the preferential phagocytic mechanism for Borrelia burgdorferi

30 September 2017

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Fc- and non-Fc-mediated phagocytosis of Borrelia burgdorferi by macrophages

30 September 2017

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TRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferi

30 September 2017

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Borrelia burgdorferi resistance to a major skin antimicrobial peptide is independent of outer surface lipoprotein content

29 June 2018

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Recruitment of macrophages and polymorphonuclear leukocytes in Lyme carditis

29 June 2018

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Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation

29 June 2018

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The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages.

29 June 2018

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Identification of an ospC operator critical for immune evasion of Borrelia burgdorferi

22 September 2018

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Artificial regulation of ospC expression in Borrelia burgdorferi

22 September 2018

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Borrelia burgdorferi sensu stricto invasiveness is correlated with OspC-plasminogen affinity

22 September 2018

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Borrelia burgdorferi are susceptible to killing by a variety of human polymorphonuclear leukocyte components

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645385

Lyme borreliosis in genetically resistant and susceptible mice with severe combined immunodeficiency

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645385

Human Phagocytic Cells in the Early Innate Immune Response toBorrelia burgdorferi

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645385

The Spirochetal Etiology of Lyme Disease

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645385

Borrelia burgdorferi--induced oxidative burst, calcium mobilization, and phagocytosis of human neutrophils are complement dependent

5 December 2018

1 reference

12 December 2020

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

1 reference

12 December 2020

Killing of Borrelia burgdorferi by macrophages is dependent on oxygen radicals and nitric oxide and can be enhanced by antibodies to outer surface proteins of the spirochete

1 reference

12 December 2020

Complementation of a Borrelia afzelii OspC mutant highlights the crucial role of OspC for dissemination of Borrelia afzelii in Ixodes ricinus

1 reference

12 December 2020

Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi

1 reference

12 December 2020

Recruited macrophages control dissemination of group A Streptococcus from infected soft tissues

1 reference

12 December 2020

MyD88 plays a unique role in host defense but not arthritis development in Lyme disease

1 reference

12 December 2020

Leukotrienes Are Essential for the Control of Leishmania amazonensis Infection and Contribute to Strain Variation in Susceptibility

1 reference

12 December 2020

Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi

1 reference

12 December 2020

Identifiers

DOI

10.1128/IAI.01215-15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26438793 AND SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26438793 AND SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

26438793

1 reference