The Role of Androgen Receptor in Breast Cancer. (Q36275556)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26568765 AND SRC:MED&resulttype=core&format=json

29 February 2020

title

The Role of Androgen Receptor in Breast Cancer (English)

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29 February 2020

1

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29 February 2020

author name string

Yassine Rechoum

series ordinal

2

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29 February 2020

Suzanne Aw Fuqua

series ordinal

3

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29 February 2020

publication date

1 January 2012

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Drug discovery today. Disease mechanisms

29 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26568765 AND SRC:MED&resulttype=core&format=json

29 February 2020

volume

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26568765 AND SRC:MED&resulttype=core&format=json

29 February 2020

issue

1-2

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29 February 2020

page(s)

e19-e27

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The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation

29 February 2020

cites work

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Expression of the androgen receptor and its correlation with molecular subtypes in 980 chinese breast cancer patients

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Androgen receptor expression is usually maintained in initial surgically resected breast cancer metastases but is often lost in end-stage metastases found at autopsy.

30 September 2017

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GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer

30 September 2017

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Targeting androgen receptor in estrogen receptor-negative breast cancer

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Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1.

30 September 2017

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Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

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Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers

30 September 2017

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30 September 2017

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A Feedback Loop between Androgen Receptor and ERK Signaling in Estrogen Receptor-Negative Breast Cancer

30 September 2017

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Androgen receptor expression and breast cancer survival in postmenopausal women

30 September 2017

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Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells

30 September 2017

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Involvement of three glutamine tracts in human androgen receptor transactivation.

30 September 2017

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Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer

30 September 2017

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Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer

30 September 2017

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Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009

30 September 2017

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Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells

30 September 2017

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Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate

30 September 2017

1 reference

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PET imaging of steroid receptor expression in breast and prostate cancer

30 September 2017

1 reference

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Aromatase inhibitors: are there differences between steroidal and nonsteroidal aromatase inhibitors and do they matter?

30 September 2017

1 reference

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The contribution of different androgen receptor domains to receptor dimerization and signaling

30 September 2017

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Non-classical actions of testosterone: an update.

30 September 2017

1 reference

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New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

30 September 2017

1 reference

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Cell- and gene-specific regulation of primary target genes by the androgen receptor

30 September 2017

1 reference

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A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgens and androgen receptors in breast cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole

30 September 2017

1 reference

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Androgen receptor action in hormone-dependent and recurrent prostate cancer.

30 September 2017

1 reference

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An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen

30 September 2017

1 reference

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Decreased androgen receptor levels and receptor function in breast cancer contribute to the failure of response to medroxyprogesterone acetate.

30 September 2017

1 reference

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Detection of mRNA levels for the estrogen alpha, estrogen beta and androgen nuclear receptor genes in archival breast cancer tissue

30 September 2017

1 reference

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Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer

30 September 2017

1 reference

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A bioinformatics-based functional analysis shows that the specifically androgen-regulated gene SARG contains an active direct repeat androgen response element in the first intron

30 September 2017

1 reference

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Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen

30 September 2017

1 reference

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Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies.

30 September 2017

1 reference

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Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Molecular biology of the androgen receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

HER2/neu as a predictive factor in breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptor: structural domains and functional dynamics after ligand-receptor interaction.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Selective DNA binding by the androgen receptor as a mechanism for hormone-specific gene regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen-receptor-specific DNA binding to an element in the first exon of the human secretory component gene.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Role of the androgen receptor in human breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

The clinical significance of androgen receptors in breast cancer and their relation to histological and cell biological parameters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

A and B forms of the androgen receptor are present in human genital skin fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgens induce divergent proliferative responses in human breast cancer cell lines.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Estrogen, androgen, glucocorticoid, and progesterone receptors in progestin-induced regression of human breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus

30 September 2017

1 reference

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Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism

30 September 2017

1 reference

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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

30 September 2017

1 reference

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Androgen resistance caused by mutations in the androgen receptor gene.

30 September 2017

1 reference

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Androgen receptor expression in breast cancer patients tested for BRCA1 and BRCA2 mutations.

30 September 2017

1 reference

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Lack of expression of androgen receptor may play a critical role in transformation from in situ to invasive basal subtype of high-grade ductal carcinoma of the breast

29 June 2018

1 reference

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Prognostic markers in triple-negative breast cancer

29 June 2018

1 reference

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Androgen receptor and prostate-specific antigen gene polymorphisms and breast cancer in African-American women.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Identification of molecular apocrine breast tumours by microarray analysis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Study on predictive role of AR and EGFR family genes with response to neoadjuvant chemotherapy in locally advanced breast cancer in Indian women

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Prognostic value of androgen receptor expression in operable triple-negative breast cancer: a retrospective analysis based on a tissue microarray

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptor in breast cancer: expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Predictors of response to exemestane as primary endocrine therapy in estrogen receptor-positive breast cancer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptor levels and association with PIK3CA mutations and prognosis in breast cancer

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Prognostic relevance of androgen receptor detection in operable breast cancer

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

A new hormonal therapy for estrogen receptor-negative breast cancer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Transgenic introduction of androgen receptor into estrogen-receptor-, progesterone-receptor-, and androgen-receptor-negative breast cancer cells renders them responsive to hormonal manipulation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Immunohistochemical study of androgen receptors in breast carcinoma. Evidence of their frequent expression in lobular carcinoma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptors are frequently expressed in mammary and extramammary Paget's disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen pathway dysregulation in BRCA1-mutated breast tumors

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

New androgen response elements in the murine pem promoter mediate selective transactivation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Change of specificity mutations in androgen-selective enhancers. Evidence for a role of differential DNA binding by the androgen receptor.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Androgen receptor CAG polymorphism and prostate cancer risk

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

Medroxyprogesterone acetate therapy in advanced breast cancer: the predictive value of androgen receptor expression

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4643279

The polymorphic CAG repeat of the androgen receptor gene: a potential role in breast cancer in women over 40

5 December 2018

1 reference

12 December 2020

Coordinated expression of oestrogen and androgen receptors in HER2-positive breast carcinomas: impact on proliferative activity

1 reference

12 December 2020

Androgen receptor expression is a significant prognostic factor in estrogen receptor positive breast cancers

1 reference

12 December 2020

The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors

1 reference

12 December 2020

Functional interplay between two response elements with distinct binding characteristics dictates androgen specificity of the mouse sex-limited protein enhancer

1 reference

12 December 2020

Androgen specificity of a response unit upstream of the human secretory component gene is mediated by differential receptor binding to an essential androgen response element

1 reference

12 December 2020

Interplay between two hormone-independent activation domains in the androgen receptor

1 reference

12 December 2020

Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells

1 reference

12 December 2020

Improved measurement of androgen receptors in human breast cancer

1 reference

12 December 2020

Microsatellite profile in hormonal receptor genes associated with breast cancer

1 reference

12 December 2020

Androgen receptor expression in primary breast cancer and its predictive and prognostic value in patients treated with neoadjuvant chemotherapy

1 reference

12 December 2020

Shorter CAG repeat length in the androgen receptor gene is associated with more aggressive forms of breast cancer

1 reference

12 December 2020

A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences

1 reference

12 December 2020

Estrogen-metabolizing enzymes in breast cancers from women over the age of 80 years

1 reference

12 December 2020

Evaluation of the prognostic significance of androgen receptor expression in metastatic breast cancer

1 reference

12 December 2020

Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues

1 reference

12 December 2020

A Phase II Clinical Trial of Flutamide in the Treatment of Advanced Breast Cancer

1 reference

12 December 2020

10.1016/J.DDMEC.2012.11.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26568765 AND SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26568765 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

26568765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26568765 AND SRC:MED&resulttype=core&format=json