MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis (Q36274514)

13 August 2017

MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

13 August 2017

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Jihong Kang

1

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13 August 2017

Serge Rivest

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

1 December 2007

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13 August 2017

12

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inferred from page(s)

published in

Journal of Cell Biology

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13 August 2017

179

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13 August 2017

6

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13 August 2017

1219-1230

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describes a project that uses

13 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2140021/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

30 September 2017

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Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin

30 September 2017

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Onset and progression in inherited ALS determined by motor neurons and microglia

30 September 2017

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Pathogen recognition and innate immunity

30 September 2017

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Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

30 September 2017

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Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis

30 September 2017

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Innate immunity: the missing link in neuroprotection and neurodegeneration?

30 September 2017

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Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

30 September 2017

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Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

30 September 2017

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

30 September 2017

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

30 September 2017

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

30 September 2017

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Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.

30 September 2017

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

29 June 2018

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Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues.

21 January 2018

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Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS.

21 January 2018

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Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

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Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia

21 January 2018

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Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

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Origin and distribution of bone marrow-derived cells in the central nervous system in a mouse model of amyotrophic lateral sclerosis

21 January 2018

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Modulation of the innate immune response by NMDA receptors has neuropathological consequences.

21 January 2018

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Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

22 September 2018

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

22 September 2018

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12 December 2020

Tumor necrosis factor alpha but not interleukin 1 beta mediates neuroprotection in response to acute nitric oxide excitotoxicity

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12 December 2020

An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia

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12 December 2020

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

1 reference

12 December 2020

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

12 December 2020

Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200705046

1 reference

13 August 2017

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13 August 2017

PubMed publication ID

18086918

1 reference