Rapid tumor induction in zebrafish by TALEN-mediated somatic inactivation of the retinoblastoma1 tumor suppressor rb1 (Q36273681)

13 August 2017

Rapid tumor induction in zebrafish by TALEN-mediated somatic inactivation of the retinoblastoma1 tumor suppressor rb1 (English)

1 reference

13 August 2017

0 references

1 reference

Staci L Solin

1

1 reference

13 August 2017

Heather R Shive

2

1 reference

13 August 2017

Kevin D Woolard

3

1 reference

13 August 2017

Jeffrey J Essner

4

1 reference

13 August 2017

Maura McGrail

5

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13 August 2017

language of work or name

English

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publication date

8 September 2015

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13 August 2017

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13 August 2017

5

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13 August 2017

13745

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Creative Commons Attribution 4.0 International

13 August 2017

start time

8 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish

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Inactivation of the retinoblastoma gene yields a mouse model of malignant colorectal cancer

30 September 2017

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Oncogenic KRAS promotes malignant brain tumors in zebrafish

30 September 2017

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Modeling cancer using genetically engineered mice.

30 September 2017

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How does multistep tumorigenesis really proceed?

30 September 2017

1 reference

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Molecular and cellular characterization of a zebrafish optic pathway tumor line implicates glia-derived progenitors in tumorigenesis.

30 September 2017

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Glial cell development and function in zebrafish

30 September 2017

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Rapid modelling of cooperating genetic events in cancer through somatic genome editing

30 September 2017

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

30 September 2017

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The Rb-E2F transcriptional regulatory pathway in tumor angiogenesis and metastasis

30 September 2017

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Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway

30 September 2017

1 reference

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Mouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studies

30 September 2017

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The somatic genomic landscape of glioblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Zebrafish cancer: the state of the art and the path forward

30 September 2017

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The CRISPR system--keeping zebrafish gene targeting fresh

30 September 2017

1 reference

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Glioma is formed by active Akt1 alone and promoted by active Rac1 in transgenic zebrafish

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

30 September 2017

Genetics of adult glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

The tumor suppressor gene retinoblastoma-1 is required for retinotectal development and visual function in zebrafish

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

TALENs: a widely applicable technology for targeted genome editing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Review: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Clonal selection drives genetic divergence of metastatic medulloblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

An animal model of MYC-driven medulloblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Guidelines for the welfare and use of animals in cancer research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

The Rb/E2F pathway: expanding roles and emerging paradigms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

In vivo genome editing using a high-efficiency TALEN system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Zebrafish models for human cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

The first knockout mouse model of retinoblastoma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642565

Cooperative tumorigenic effects of germline mutations in Rb and p53

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26345384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heterozygous Rb-1 delta 20/ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26345384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP13745

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

26345384

1 reference