Transcriptomic characterization of fibrolamellar hepatocellular carcinoma (Q36268536)

13 August 2017

Transcriptomic characterization of fibrolamellar hepatocellular carcinoma (English)

1 reference

fibrolamellar hepatocellular carcinoma

13 August 2017

0 references

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10

Umesh K Bhanot

1 reference

13 August 2017

Brian D Dill

8

0 references

Sanford M Simon

object named as

Sanford M Simon

13

0 references

Elana P. Simon

1

object named as

Elana P Simon

1 reference

13 August 2017

Catherine A Freije

2

1 reference

13 August 2017

Benjamin A Farber

3

1 reference

13 August 2017

Gadi Lalazar

4

1 reference

13 August 2017

David G Darcy

5

1 reference

13 August 2017

Joshua N Honeyman

6

1 reference

13 August 2017

Rachel Chiaroni-Clarke

7

1 reference

13 August 2017

Henrik Molina

9

1 reference

13 August 2017

Michael P La Quaglia

11

1 reference

13 August 2017

Brad R Rosenberg

12

1 reference

13 August 2017

language of work or name

English

0 references

publication date

21 October 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

1 reference

13 August 2017

112

1 reference

13 August 2017

44

1 reference

13 August 2017

E5916-25

1 reference

describes a project that uses

13 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4640752

inferred from PubMed Central ID database lookup

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Extracellular metabolic energetics can promote cancer progression

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The extracellular matrix modulates the hallmarks of cancer

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Genomic analysis of fibrolamellar hepatocellular carcinoma

30 September 2017

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Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma

30 September 2017

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30 September 2017

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HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors.

30 September 2017

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Fibrolamellar carcinoma: 2012 update

30 September 2017

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Genetics and epigenetics of adrenocortical tumors.

30 September 2017

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The expression of CD90/Thy-1 in hepatocellular carcinoma: an in vivo and in vitro study

30 September 2017

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Prognostic indicators and treatment outcome in 94 cases of fibrolamellar hepatocellular carcinoma

30 September 2017

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Chromogranin A, Ki-67 index and IGF-related genes in patients with neuroendocrine tumors

30 September 2017

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Influence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A.

30 September 2017

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A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

30 September 2017

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COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer

30 September 2017

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Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

30 September 2017

1 reference

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Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

30 September 2017

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Clinicopathologic characteristics and survival outcomes of patients with fibrolamellar carcinoma: data from the fibrolamellar carcinoma consortium

30 September 2017

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The Hippo pathway: regulators and regulations

30 September 2017

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SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression

30 September 2017

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OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration

30 September 2017

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GSVA: gene set variation analysis for microarray and RNA-seq data.

30 September 2017

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WNT signalling pathways as therapeutic targets in cancer

30 September 2017

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Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1.

30 September 2017

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Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas.

30 September 2017

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30 September 2017

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Assembly of allosteric macromolecular switches: lessons from PKA

30 September 2017

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A systematic review: treatment and prognosis of patients with fibrolamellar hepatocellular carcinoma

30 September 2017

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Comprehensive molecular characterization of human colon and rectal cancer

30 September 2017

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Wnt/β-catenin signaling and disease

30 September 2017

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

30 September 2017

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Fast gapped-read alignment with Bowtie 2

30 September 2017

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Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer

30 September 2017

1 reference

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PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism

30 September 2017

1 reference

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Activator protein-2α functions as a master regulator of multiple transcription factors in the mouse liver

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Krüppel-like Factor 4 (KLF4) Activates the Transcription of the Gene for the Platelet Isoform of Phosphofructokinase (PFKP) in Breast Cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Differential expression analysis for sequence count data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

NANETS consensus guidelines for the diagnosis of neuroendocrine tumor

30 September 2017

1 reference

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p130Cas is an essential transducer element in ErbB2 transformation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Constitutive activation of nuclear factor-kappa B (NF-kB) signaling pathway in fibrolamellar hepatocellular carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Mucins in cancer: function, prognosis and therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Differential regulation of ErbB2 expression by cAMP-dependent protein kinase in tamoxifen-resistant breast cancer cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Aurora kinases: new targets for cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Lung cancer: intragenic ERBB2 kinase mutations in tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Aurora A, meiosis and mitosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Overexpression and amplification of Aurora-A in hepatocellular carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Aromatase inhibitors for breast cancer: lessons from the laboratory

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Fibrolamellar hepatocellular carcinoma in children and adolescents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Protein kinase A-dependent cooperation between GATA and CCAAT/enhancer-binding protein transcription factors regulates steroidogenic acute regulatory protein promoter activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

ERM transactivation is up-regulated by the repression of DNA binding after the PKA phosphorylation of a consensus site at the edge of the ETS domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

E2f3 is critical for normal cellular proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Treatment of fibrolamellar hepatoma with subtotal hepatectomy or transplantation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Activation of NF-kappa B in vivo is regulated by multiple phosphorylations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Regulation of transcription by cyclic AMP-dependent protein kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Fibrolamellar carcinoma of the liver: an immunohistochemical study of nineteen cases and a review of the literature

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Synaptophysin expression in neuroendocrine neoplasms as determined by immunocytochemistry.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Transthyretin in endocrine pancreatic tumors

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Fibronectin patterns in hepatocellular carcinoma and its clinical significance

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Germline PRKACA amplification leads to Cushing syndrome caused by 3 adrenocortical pathologic phenotypes.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Transcriptional profiling of pure fibrolamellar hepatocellular carcinoma reveals an endocrine signature.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Fibrolamellar variant of hepatocellular carcinoma does not have a better survival than conventional hepatocellular carcinoma--results and treatment recommendations from the Childhood Liver Tumour Strategy Group (SIOPEL) experience

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4640752

The control of glycolysis and gluconeogenesis by protein phosphorylation

22 September 2018

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12 December 2020

Gynecomastia as a presenting sign of fibrolamellar carcinoma of the liver

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12 December 2020

Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation

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12 December 2020

Excessive collagen formation in fibrolamellar carcinoma of the liver: a morphological and biochemical study

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12 December 2020

Fibrolamellar carcinoma of the liver: A tumor of adolescents and young adults with distinctive clinico-pathologic features

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12 December 2020

Amplification/overexpression of a mitotic kinase gene in human bladder cancer

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12 December 2020

E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer

1 reference

12 December 2020

Hepatocellular carcinomas show abnormal expression of fibronectin protein

1 reference

12 December 2020

Molecular Basis of Severe Gynecomastia Associated with Aromatase Expression in a Fibrolamellar Hepatocellular Carcinoma1

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12 December 2020

Abundant expression of cytokeratin 7 in fibrolamellar carcinoma of the liver

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12 December 2020

Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways

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12 December 2020

Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study

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12 December 2020

Differential diagnosis of tumors and tumor-like lesions of liver in infancy and childhood

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12 December 2020

A childhood fibrolamellar hepatocellular carcinoma with increased aromatase activity and a near triploid karyotype

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1424894112

1 reference

13 August 2017

0 references

1 reference

13 August 2017

PubMed publication ID

26489647

1 reference