The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin. (Q36247095)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16138117 AND SRC:MED&resulttype=core&format=json

6 January 2020

review article

1 reference

title

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin (English)

1 reference

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6 January 2020

3

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6 January 2020

author name string

V Baron

1

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6 January 2020

E D Adamson

2

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6 January 2020

G Ragona

4

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6 January 2020

D Mercola

5

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6 January 2020

publication date

1 February 2006

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6 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16138117 AND SRC:MED&resulttype=core&format=json

6 January 2020

volume

13

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6 January 2020

issue

2

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6 January 2020

page(s)

115-124

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Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53

6 January 2020

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1 reference

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1 October 2017

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Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence

1 October 2017

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Egr1 promotes growth and survival of prostate cancer cells. Identification of novel Egr1 target genes

1 October 2017

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1 October 2017

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The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

1 October 2017

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Introduction of DNA enzyme for Egr-1 into tubulointerstitial fibroblasts by electroporation reduced interstitial alpha-smooth muscle actin expression and fibrosis in unilateral ureteral obstruction (UUO) rats

1 October 2017

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1 October 2017

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PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

1 October 2017

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Frequent and early loss of the EGR1 corepressor NAB2 in human prostate carcinoma

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Implications of cell death regulation in the pathogenesis and treatment of prostate cancer

1 October 2017

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1 October 2017

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p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis

1 October 2017

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CpG oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from anti-IgM-mediated growth inhibition by up-regulation of egr-1.

1 October 2017

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The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1.

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EGR-1, the reluctant suppression factor: EGR-1 is known to function in the regulation of growth, differentiation, and also has significant tumor suppressor activity and a mechanism involving the induction of TGF-beta1 is postulated to account for th

1 October 2017

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1 October 2017

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1 October 2017

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22 September 2018

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22 September 2018

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Regulation of constitutive expression of mouse PTEN by the 5'-untranslated region

22 September 2018

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12 December 2020

Tissue fibronectin levels of human prostatic cancer, as a tumor marker

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12 December 2020

Method for cloning in vivo targets of the Egr-1 transcription factor

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12 December 2020

Increased Expression of Early Growth Response-1 Messenger Ribonucleic Acid in Prostatic Adenocarcinoma

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12 December 2020

Early stimulation and late inhibition of peroxisome proliferator-activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator p

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Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation

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12 December 2020

Non-random distribution of spontaneous chromosome aberrations in two Bloom Syndrome patients

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12 December 2020

Molecular heterogeneity and function of EWS-WT1 fusion transcripts in desmoplastic small round cell tumors

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12 December 2020

High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGF-beta

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12 December 2020

Suppression of transformed phenotypes of human fibrosarcoma cells by overexpression of recombinant fibronectin

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12 December 2020

Substrate specificity of alpha(v)beta(3) integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activation

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12 December 2020

Regulation of beta1C and beta1A integrin expression in prostate carcinoma cells.

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Crossref

https://api.crossref.org/works/10.1038/SJ.CGT.7700896

7 January 2021

inferred from DOI database lookup

EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer

1 reference

Crossref

https://api.crossref.org/works/10.1038/SJ.CGT.7700896

7 January 2021

inferred from DOI database lookup

Insights into differential endostatin activity

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Crossref

https://api.crossref.org/works/10.1038/SJ.CGT.7700896

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.CGT.7700896

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16138117 AND SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16138117 AND SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

16138117

1 reference