Getting under the skin: the immunogenetics of psoriasis (Q36247085)

13 August 2017

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title

Getting under the skin: the immunogenetics of psoriasis (English)

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Erratum: Getting under the skin: the immunogenetics of psoriasis

13 August 2017

corrigendum / erratum

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author

Anne M. Bowcock

series ordinal

1

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13 August 2017

2

James G Krueger

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13 August 2017

publication date

1 September 2005

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Nature Reviews Immunology

13 August 2017

published in

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13 August 2017

volume

5

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13 August 2017

issue

9

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13 August 2017

page(s)

699-711

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Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system

13 August 2017

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CD8 T cells in psoriatic lesions preferentially use T-cell receptor V beta 3 and/or V beta 13.1 genes

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CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

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Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

21 January 2018

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The immunologic basis for the treatment of psoriasis with new biologic agents

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Dermal injection of immunocytes induces psoriasis

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Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

21 January 2018

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Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling

21 January 2018

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Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors.

21 January 2018

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CCL27-CCR10 interactions regulate T cell-mediated skin inflammation

21 January 2018

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Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array

21 January 2018

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Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

21 January 2018

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Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development

21 January 2018

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Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression

21 January 2018

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CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry.

21 January 2018

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The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiat

21 January 2018

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Perforin and granzyme B may contribute to skin inflammation in atopic dermatitis and psoriasis

21 January 2018

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Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

21 January 2018

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Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

21 January 2018

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Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

21 January 2018

1 reference

Dysfunctional blood and target tissue CD4 CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

21 January 2018

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Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines

21 January 2018

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Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

21 January 2018

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Stat3 regulates genes common to both wound healing and cancer

21 January 2018

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Psoriasis in Australian twins.

21 January 2018

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A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families

21 January 2018

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A genome-wide search for human type 1 diabetes susceptibility genes

21 January 2018

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Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families

21 January 2018

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Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

21 January 2018

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Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.

21 January 2018

1 reference

Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN).

21 January 2018

1 reference

Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus

21 January 2018

1 reference

Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus

21 January 2018

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A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele

21 January 2018

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Transgenic mouse models support HCR as an effector gene in the PSORS1 locus

21 January 2018

1 reference

A non-HLA gene within the MHC in psoriasis

21 January 2018

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Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders

21 January 2018

1 reference

Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation

21 January 2018

1 reference

Corneodesmosin, a component of epidermal corneocyte desmosomes, displays homophilic adhesive properties

21 January 2018

1 reference

Identification of six novel polymorphisms in the human corneodesmosin gene

21 January 2018

1 reference

A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice

21 January 2018

1 reference

Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q

21 January 2018

1 reference

A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis

21 January 2018

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Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family

21 January 2018

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The immunological synapse.

21 January 2018

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The nature of molecular recognition by T cells

21 January 2018

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Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor

21 January 2018

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

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Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis.

21 January 2018

1 reference

Mapping of psoriasis to 17q terminus.

21 January 2018

1 reference

S100 proteins in the epidermis

21 January 2018

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Differentially expressed late constituents of the epidermal cornified envelope

21 January 2018

1 reference

Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.

21 January 2018

1 reference

Molecular physiology of cation-coupled Cl? cotransport: the SLC12 family

21 January 2018

1 reference

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

21 January 2018

1 reference

Functional variants of OCTN cation transporter genes are associated with Crohn disease

21 January 2018

1 reference

PDZK1: I. a major scaffolder in brush borders of proximal tubular cells

21 January 2018

1 reference

Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases

21 January 2018

1 reference

Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13.

21 January 2018

1 reference

A major non-HLA locus in celiac disease maps to chromosome 191 1This study is dedicated to the memory of Lodewijk Sandkuijl (1953–2002), who died shortly after its completion. He was an inspiration to us and was a world expert on biostatistics

21 January 2018

1 reference

Association of intercellular adhesion molecule-1 gene with type 1 diabetes

21 January 2018

1 reference

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

21 January 2018

1 reference

Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci

21 January 2018

1 reference

A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting

21 January 2018

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Molecular mechanisms that set the stage for DC-T cell engagement.

21 January 2018

1 reference

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

21 January 2018

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

21 January 2018

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Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

21 January 2018

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Proximal protein tyrosine kinases in immunoreceptor signaling

21 January 2018

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Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder

21 January 2018

1 reference

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

21 January 2018

1 reference

Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope

21 January 2018

1 reference

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes

21 January 2018

1 reference

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

21 January 2018

1 reference

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

21 January 2018

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Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

21 January 2018

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Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype

21 January 2018

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Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis

21 January 2018

1 reference

IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity

21 January 2018

1 reference

Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia

21 January 2018

1 reference

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

21 January 2018

1 reference

Murine psoriasis-like disorder induced by naive CD4 T cells

21 January 2018

1 reference

Interleukin 20: discovery, receptor identification, and role in epidermal function

21 January 2018

1 reference

Searching for Psoriasis Susceptibility Genes in Italy: Genome Scan and Evidence for a New Locus on Chromosome 1

21 January 2018

1 reference

21 January 2018

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Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris

31 March 2020

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Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris

31 March 2020

1 reference

Chimaeric CD4 monoclonal antibody in treatment of generalised pustular psoriasis

31 March 2020

1 reference

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

31 March 2020

1 reference

Development of psoriasis after syngeneic bone marrow transplant from psoriatic donor: further evidence for adoptive autoimmunity

31 March 2020

1 reference

Transmission of psoriatic arthritis by allogeneic bone marrow transplantation for chronic myelogenous leukaemia from an HLA-identical donor

31 March 2020

1 reference

Psoriasis and alpha-interferon

31 March 2020

1 reference

Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris

31 March 2020

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Intraepidermal lymphocytes in psoriatic lesions are activated GMP‐17(TIA‐1) CD8 CD3 CTLs as determined by phenotypic analysis

31 March 2020

1 reference

Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles

31 March 2020

1 reference

Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin

31 March 2020

1 reference

Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases

31 March 2020

1 reference

A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

31 March 2020

1 reference

Psoriasis in an Unselected Series of Twins

31 March 2020

1 reference

Natural history of psoriasis in 61 twin pairs

31 March 2020

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'Twin' psoriasis in monozygotic twins

31 March 2020

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Psoriasis Genetics: The Way Forward

31 March 2020

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31 March 2020

Psoriasis and HLA-Cw6

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Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes

31 March 2020

1 reference

Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis

31 March 2020

1 reference

The apical Na( )/H( ) exchanger isoform NHE3 is regulated by the actin cytoskeleton

31 March 2020

1 reference

Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly

31 March 2020

1 reference

The genetics of psoriasis: a complex disorder of the skin and immune system

31 March 2020

1 reference

Expression of small proline rich proteins in neoplastic and inflammatory skin diseases

31 March 2020

1 reference

Inflammatory Bowel Disease Is Linked to 19p13 and Associated with ICAM-1

31 March 2020

1 reference

A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage

31 March 2020

1 reference

Genetic variants of Complex I in multiple sclerosis

31 March 2020

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Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo

31 March 2020

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CD8( ) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1689

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13 August 2017

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