Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis (Q36241244)

13 August 2017

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title

Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis (English)

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13 August 2017

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Luigi Strizzi

1

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13 August 2017

Caterina Bianco

series ordinal

2

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13 August 2017

Nicola Normanno

series ordinal

3

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13 August 2017

David Salomon

series ordinal

4

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13 August 2017

language of work or name

English

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publication date

1 August 2005

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13 August 2017

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13 August 2017

volume

24

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13 August 2017

issue

37

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13 August 2017

page(s)

5731-5741

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Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Cripto-1 indirectly stimulates the tyrosine phosphorylation of erb B-4 through a novel receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Role of human cripto-1 in tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

The epidermis: rising to the surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Cripto forms a complex with activin and type II activin receptors and can block activin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Establishment of vertebrate left-right asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Formation and function of Spemann's organizer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Heregulin-dependent autocrine loop regulates growth of K-ras but not erbB-2 transformed rat thyroid epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

The stem cell niche: theme and variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Gastrula organiser and embryonic patterning in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Context-dependent neuronal differentiation and germ layer induction of Smad4-/- and Cripto-/- embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Xantivin suppresses the activity of EGF-CFC genes to regulate nodal signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

A novel epidermal growth factor-like molecule containing two follistatin modules stimulates tyrosine phosphorylation of erbB-4 in MKN28 gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Signaling in stem cell niches: lessons from the Drosophila germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Expression of messenger RNA for amphiregulin, heregulin, and cripto-1, three new members of the epidermal growth factor family, in human breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Tissue repair and stem cell renewal in carcinogenesis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Axis development and early asymmetry in mammals

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Detection and localization of Cripto-1 binding in mouse mammary epithelial cells and in the mouse mammary gland using an immunoglobulin-cripto-1 fusion protein

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Role of the cripto (EGF-CFC) family in embryogenesis and cancer.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Identification of Cripto-1 in human milk

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Induction and regulation of epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

The immunohistochemical detection of cripto-1 in benign and malignant human bladder

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Two modes by which Lefty proteins inhibit nodal signaling

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Interference with brachyury function inhibits convergent extension, causes apoptosis, and reveals separate requirements in the FGF and activin signalling pathways

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto-1 induces apoptosis in HC-11 mouse mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto-1-induced increase in vimentin expression is associated with enhanced migration of human Caski cervical carcinoma cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Repressed E-cadherin expression in the lower crypt of human small intestine: a cell marker of functional relevance

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

The EGF-CFC protein one-eyed pinhead is essential for nodal signaling

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Generation of pluripotent stem cells from neonatal mouse testis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Wnt signaling and the regulation of stem cell function

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Morphogen gradients: nodal enters the stage

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Expression of cripto, a novel gene of the epidermal growth factor family, in human gastrointestinal carcinomas

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Characterization of the mouse Tdgf1 gene and Tdgf pseudogenes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Requirement for Wnt3 in vertebrate axis formation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Mechanisms of germ-cell specification in mouse embryos

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Membrane-anchorage of Cripto protein by glycosylphosphatidylinositol and its distribution during early mouse development

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto: roles in mammary cell growth, survival, differentiation and transformation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Preneoplastic mammary tumor markers: Cripto and Amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Differential immunohistochemical detection of transforming growth factor α, amphiregulin and CRIPTO in human normal and malignant breast tissues

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Expression of transforming growth factor alpha, amphiregulin and cripto-1 in human breast carcinomas.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Stem cells, cancer, and cancer stem cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Nodal Signaling in Vertebrate Development

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Nodal signalling in vertebrate development.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Stem cell origin of cancer and differentiation therapy

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Purification and Characterization of a Recombinant Human Cripto-1 Protein

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

The EGF-CFC gene family in vertebrate development.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Frequent immunohistochemical detection of EGF supergene family members in ovarian carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Morphogens, their identification and regulation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Epithelial-mesenchymal transitions in tumour progression

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Epithelial cell plasticity in development and tumor progression

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Activin- and Nodal-related factors control antero–posterior patterning of the zebrafish embryo

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Expression of cripto in human pancreatic tumors.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

One-eyed pinhead regulates cell motility independent of Squint/Cyclops signaling

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Cripto-1 enhances migration and branching morphogenesis of mouse mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Human Cripto-1 overexpression in the mouse mammary gland results in the development of hyperplasia and adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Molecular basis of basal cell carcinoma: analysis of differential gene expression by differential display PCR and expression array

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Specific Arrest of Cardiogenesis in Cultured Embryonic Stem Cells Lacking Cripto-1

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Wnt-dependent regulation of the E-cadherin repressor snail

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Positional Cloning Identifies Zebrafish one-eyed pinhead as a Permissive EGF-Related Ligand Required during Gastrulation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208918

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208918

1 reference

Dimensions Publication ID

13 August 2017

1049663453

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1 reference