Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines (Q36238936)

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22 December 2019

title

Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines (English)

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4

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22 December 2019

author name string

Vladimir Poltoratsky

series ordinal

1

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22 December 2019

Rajendra Prasad

series ordinal

2

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22 December 2019

Julie K Horton

series ordinal

3

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22 December 2019

publication date

28 November 2006

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22 December 2019

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22 December 2019

volume

6

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issue

2

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22 December 2019

page(s)

244-253

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describes a project that uses

22 December 2019

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

AID in somatic hypermutation and class switch recombination

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The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation

1 October 2017

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DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes

1 October 2017

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DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair

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Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

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Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions

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Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

1 October 2017

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AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

1 October 2017

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

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Interaction of DNA polymerase beta with GRIP1 during meiosis

1 October 2017

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Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair

1 October 2017

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Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

1 October 2017

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DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

1 October 2017

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5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro

1 October 2017

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Error-prone candidates vie for somatic mutation

1 October 2017

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 October 2017

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Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

1 October 2017

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1 October 2017

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Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

1 October 2017

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T cells can induce somatic mutation in B cell receptor-engaged BL2 Burkitt's lymphoma cells independently of CD40-CD40 ligand interactions

1 October 2017

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1 October 2017

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Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA.

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells.

1 October 2017

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1 October 2017

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 October 2017

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22 September 2018

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22 September 2018

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22 September 2018

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Variability in the Lambda Light Chain Sequences of Mouse Antibody

22 September 2018

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Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice

22 September 2018

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12 December 2020

DNA-dependent DNA polymerase species in male germ cells of the mouse

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12 December 2020

DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract.

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12 December 2020

Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction

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12 December 2020

10.1016/J.DNAREP.2006.10.003

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17127106 AND SRC:MED&resulttype=core&format=json

22 December 2019

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22 December 2019

PubMed publication ID

17127106

1 reference