Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity (Q36234472)

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10 February 2020

title

Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity (English)

1 reference

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10 February 2020

9

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10 February 2020

Elizabeth L. Johnson

10

1 reference

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10 February 2020

author name string

Aster Legesse-Miller

1

1 reference

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10 February 2020

Irene Raitman

2

1 reference

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10 February 2020

Erin M Haley

3

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10 February 2020

Albert Liao

4

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10 February 2020

Lova L Sun

5

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10 February 2020

David J Wang

6

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10 February 2020

Nithya Krishnan

7

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10 February 2020

Johanna M S Lemons

8

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10 February 2020

Benjamin A Lund

11

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10 February 2020

Hilary A Coller

12

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10 February 2020

publication date

8 August 2012

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Molecular Biology of the Cell

10 February 2020

published in

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10 February 2020

volume

23

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10 February 2020

issue

18

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10 February 2020

page(s)

3566-3581

1 reference

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Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes

10 February 2020

cites work

1 reference

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Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: crosstalk among proteasome, autophagy-lysosome and ER stress

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Quiescent fibroblasts exhibit high metabolic activity.

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Interplay between the ubiquitin-proteasome system and autophagy in proteinopathies.

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Protein quality control in the ER: the recognition of misfolded proteins

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Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast.

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The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death

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Reactive oxygen species and glutathione level changes by a proteasome inhibitor, MG132, partially affect calf pulmonary arterial endothelial cell death

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Hijacking HES1: how tumors co-opt the anti-differentiation strategies of quiescent cells

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Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

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Control of cell growth by the SCF and APC/C ubiquitin ligases

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Fear of commitment: Hes1 protects quiescent fibroblasts from irreversible cellular fates

1 October 2017

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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

1 October 2017

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The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib

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Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

1 October 2017

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

1 October 2017

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Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells

1 October 2017

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Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy

1 October 2017

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let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts

1 October 2017

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 October 2017

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Autophagy is activated, but is not required for the G0 function of BCL-2 or BCL-xL.

1 October 2017

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Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.

1 October 2017

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ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo

1 October 2017

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Proteasome inhibitors prevent oxidative stress-induced nerve cell death by a novel mechanism

1 October 2017

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Autophagy fights disease through cellular self-digestion

1 October 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

1 October 2017

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

1 October 2017

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Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein

1 October 2017

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Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

1 October 2017

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 October 2017

1 reference

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Autophagy suppresses tumor progression by limiting chromosomal instability

1 October 2017

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The ubiquitin-proteasome pathway in cell cycle control.

1 October 2017

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 October 2017

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A new description of cellular quiescence

1 October 2017

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 October 2017

1 reference

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

1 October 2017

1 reference

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Proteasome inhibitor therapy in multiple myeloma

1 October 2017

1 reference

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The molecular machinery of autophagy: unanswered questions

1 October 2017

1 reference

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Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma

1 October 2017

1 reference

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The role of autophagy during the early neonatal starvation period

1 October 2017

1 reference

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Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells.

1 October 2017

1 reference

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

1 October 2017

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Autophagy: in sickness and in health

1 October 2017

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1 October 2017

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Protein degradation and protection against misfolded or damaged proteins

1 October 2017

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Autophagy: a regulated bulk degradation process inside cells

1 October 2017

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Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

1 October 2017

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Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and over-expression of Bax: resistance of quiescent cells to oxidative stress

1 October 2017

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

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The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

1 October 2017

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Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

1 October 2017

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The 26S proteasome: a molecular machine designed for controlled proteolysis

1 October 2017

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Proteasome inhibitors: valuable new tools for cell biologists

1 October 2017

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Bafilomycin A1 Prevents Maturation of Autophagic Vacuoles by Inhibiting Fusion between Autophagosomes and Lysosomes in Rat Hepatoma Cell Line, H-4-II-E Cells

1 October 2017

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Nuclear Accumulation of p21Cip1 at the Onset of Mitosis: a Role at the G2/M-Phase Transition

1 October 2017

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The Active Sites of the Eukaryotic 20 S Proteasome and Their Involvement in Subunit Precursor Processing

1 October 2017

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Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance

1 October 2017

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The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase

1 October 2017

1 reference

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p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

1 October 2017

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A conditional lethal mutant in the fission yeast 26 S protease subunit mts3 is defective in metaphase to anaphase transition

1 October 2017

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Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

1 October 2017

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Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes

1 October 2017

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Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth

29 June 2018

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Excess peroxisomes are degraded by autophagic machinery in mammals

29 June 2018

1 reference

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Role of the Heat-Shock Response in the Life and Death of Proteins

29 June 2018

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Bortezomib potentially inhibits cellular growth of vascular endothelial cells through suppression of G2/M transition

29 June 2018

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Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes

22 September 2018

1 reference

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Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2.

22 September 2018

1 reference

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Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition

22 September 2018

1 reference

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The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

22 September 2018

1 reference

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Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis

22 September 2018

1 reference

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Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells

22 September 2018

1 reference

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

22 September 2018

1 reference

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2-methoxyestradiol does not inhibit superoxide dismutase

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442405

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

22 September 2018

1 reference

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p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442405

Proteolysis: from the lysosome to ubiquitin and the proteasome

21 October 2018

1 reference

12 December 2020

In quiescence of fission yeast, autophagy and the proteasome collaborate for mitochondrial maintenance and longevity

1 reference

12 December 2020

Superoxide dismutase as a target for the selective killing of cancer cells

1 reference

12 December 2020

Bafilomycin A1, a specific inhibitor of vacuolar-type H( )-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

1 reference

12 December 2020

Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells

1 reference

12 December 2020

Requirement of reactive oxygen species generation in apoptosis of leukemia cells induced by 2-methoxyestradiol

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E12-03-0192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22875985 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22875985 AND SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

22875985

1 reference