An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction (Q36227873)

12 August 2017

An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction (English)

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12 August 2017

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13

Peter A Ward

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12 August 2017

7

Firas S Zetoune

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12 August 2017

10

J Vidya Sarma

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12 August 2017

2

Laszlo M Hoesel

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12 August 2017

5

Kyros R Ipaktchi

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12 August 2017

12

Mark R Hemmila

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12 August 2017

Andreas D Niederbichler

1

object named as

Andreas D Niederbichler

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12 August 2017

Margaret V Westfall

3

1 reference

12 August 2017

Hongwei Gao

4

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12 August 2017

Lei Sun

6

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12 August 2017

Grace L Su

8

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12 August 2017

Saman Arbabi

9

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12 August 2017

Stewart C Wang

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12 August 2017

language of work or name

English

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publication date

27 December 2005

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Journal of Experimental Medicine

12 August 2017

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12 August 2017

203

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12 August 2017

1

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12 August 2017

53-61

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Increased leakage of sarcoplasmic reticulum Ca2 contributes to abnormal myocyte Ca2 handling and shortening in sepsis

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Evaluating myocardial depression in sepsis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Role of C5a-C5aR interaction in sepsis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

The epidemiology of sepsis in the United States from 1979 through 2000

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Ca(2 )-handling proteins and heart failure: novel molecular targets?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Lysozyme: a mediator of myocardial depression and adrenergic dysfunction in septic shock in dogs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Myocardial dysfunction in the patient with sepsis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Increased C5a receptor expression in sepsis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Expression and function of the C5a receptor in rat alveolar epithelial cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Myocardial dysfunction in septic shock

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Cardiac contractility and structure are not significantly compromised even during the late, hypodynamic stage of sepsis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Activation of the complement system in baboons challenged with live Escherichia coli: correlation with mortality and evidence for a biphasic activation pattern

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

The third component of complement protects against Escherichia coli endotoxin-induced shock and multiple organ failure.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Endotoxin-induced shock in the rat. A role for C5a

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

The epidemiology of severe sepsis in children in the United States

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Tumor necrosis factor in the heart.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Adenovirus-mediated myofilament gene transfer into adult cardiac myocytes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Regulation by C5a of neutrophil activation during sepsis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Neutrophil C5a receptor and the outcome in a rat model of sepsis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Sepsis-induced depressed contractile function of isolated ventricular myocytes is due to altered calcium transient properties

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Altered phospholamban-calcium ATPase interaction in cardiac sarcoplasmic reticulum during the progression of sepsis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Protective effects of C5a blockade in sepsis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

TNF-alpha and myocardial depression in endotoxemic rats: temporal discordance of an obligatory relationship.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118072

Macrophage migration inhibitory factor is a cardiac-derived myocardial depressant factor

22 September 2018

1 reference

12 December 2020

Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis

1 reference

12 December 2020

A global perspective on the epidemiology of sepsis

1 reference

12 December 2020

Anaphylatoxin formation in sepsis

1 reference

12 December 2020

Differential Alterations in Cardiovascular Responses During the Progression of Polymicrobial Sepsis in the Mouse

1 reference

12 December 2020

C5a receptor and thymocyte apoptosis in sepsis

1 reference

12 December 2020

The anaphylatoxins C3a and C5a are vasodilators in the canine coronary vasculaturein vitro andin vivo

1 reference

12 December 2020

Serum complement levels and severity of sepsis

1 reference

12 December 2020

Structure–Function Relationships in the Septic Rat Heart

1 reference

12 December 2020

Protein kinase C activity is increased in rat heart during the early hyperdynamic phase of sepsis

1 reference

12 December 2020

Histamine H3 activation depresses cardiac function in experimental sepsis

1 reference

12 December 2020

Reversal of hypocalcemia and decreased afterload in sepsis. Effect on myocardial systolic and diastolic function

1 reference

12 December 2020

Complement activation as a cause of transient hypotension during plasmapheresis

1 reference

12 December 2020

Treating patients with severe sepsis

1 reference

12 December 2020

Protective effects of anti-C5a peptide antibodies in experimental sepsis

1 reference

12 December 2020

Expression and function of C5a receptor in mouse microvascular endothelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20051207

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

16380509

1 reference